Role of a Novel Toll-like Receptor in Response to Viral Infection

新型 Toll 样受体在病毒感染反应中的作用

• 批准号: 8090890
• 负责人: Dekai Zhang
• 金额: $ 29.3万
• 依托单位: TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8090890
• 关键词: Antibodies; Antiviral Response; Biochemical; Biochemical Genetics; Biological; Biology; Cell surface; Cells; Databases; Dendritic Cells; Detection; Expressed Sequence Tags; Family; Future; Genbank; Genes; Host Defense; Human; Immune response; Immune system; Inflammation Mediators; Integral Membrane Protein; Interferon Type I; Interferons; Interleukin-1; Knockout Mice; Ligands; Mediating; Molecular; Molecular Genetics; Mus; Natural Immunity; Nucleic Acids; Pattern; Phase; Play; Proteins; Receptor Signaling; Respiratory syncytial virus; Role; Signal Pathway; Signal Transduction; TLR3 gene; Testing; Toll-like receptors; Viral; Virus; Virus Diseases; defense response; genome database; insight; member; microorganism; mouse model; novel; pathogen; receptor; response; sensor; vaccination strategy

项目成果

A novel Toll-like receptor that recognizes vesicular stomatitis virus.

一种识别水泡性口炎病毒的新型 Toll 样受体。

• 发表时间: 2011-02-11
• 作者: Shi, Zhongcheng;Cai, Zhenyu;Sanchez, Amir;Zhang, Tingting;Wen, Shu;Wang, Jun;Yang, Jianhua;Fu, Songbin;Zhang, Dekai
• 通讯作者: Zhang, Dekai

Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth.

鞭毛蛋白激活乳腺癌细胞上的 Toll 样受体 5 可抑制细胞增殖和肿瘤生长。

• DOI: 10.1158/0008-5472.can-10-1993
• 发表时间: 2011-04-01
• 期刊: Cancer research
• 影响因子: 11.2
• 作者: Cai Z;Sanchez A;Shi Z;Zhang T;Liu M;Zhang D
• 通讯作者: Zhang D