Oral mucosal SHIV VLP vaccination against HIV

口腔粘膜 SHIV VLP 疫苗接种预防 HIV

• 批准号: 8112140
• 负责人: Qizhi C. Yao
• 金额: $ 17.65万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8112140
• 关键词: Adherence; Antibodies; Antigen Presentation; Antigen-Presenting Cells; Antigens; B-Cell Activation; B-Lymphocytes; Binding; CD4 Positive T Lymphocytes; CD40 Ligand; Cell Maturation; Cells; Cervical lymph node group; Clinical Trials; Data; Dendritic Cells; Dendritic cell activation; Disease; Engineering; Future; Gagging; Genetic Engineering; Goals; HIV; HIV Infections; HIV vaccine; Human; Immune; Immune response; Immunization; Immunoglobulin A; In Vitro; Infection; Injection of therapeutic agent; Life; Macaca mulatta; Membrane; Memory; Modeling; Monkeys; Mucosal Immune Responses; Mucosal Immunity; Mucous Membrane; Mus; Oral; Oral mucous membrane structure; Oropharyngeal; Production; Proteins; Regimen; Route; SIV; Sampling; Signal Transduction; Solid; Structure of germinal center of lymph node; Surface; T cell response; T-Cell Depletion; Technology; Testing; Vaccination; Vaccines; Viral Load result; Virus; Virus-like particle; base; cytokine; design; lymph nodes; mucosal site; mucosal vaccination; mucosal vaccine; nonhuman primate; novel; novel strategies; novel vaccines; pathogen; prevent; protective effect; protective efficacy; public health relevance; response; simian human immunodeficiency virus; targeted delivery; vaccination strategy; vaccine candidate; vaccine delivery