10th International Post-Symposium Research Conference on Recent Advances in Otiti

第十届奥蒂蒂最新进展国际会后研究会议

• 批准号: 8061824
• 负责人: Lauren O Bakaletz
• 金额: $ 4万
• 依托单位: RESEARCH INST NATIONWIDE CHILDREN'S HOSP
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-12-13 至 2011-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8061824
• 关键词: Animal Model; Area; Biomedical Research; Cellular biology; Clinical; Collaborations; Communication; Consensus; Development; Diagnosis; Discipline; Disease; Epidemiology; Etiology; Funding; Future; Genetic; Goals; Head and Neck Surgery; Health; Immunology; Individual; International; Journals; Knowledge; Lead; Microbial Biofilms; Microbiology; Molecular; Molecular Biology; Molecular Immunology; Molecular and Cellular Biology; Movement; National Institute on Deafness and Other Communication Disorders; Natural Immunity; Nature; Otitis; Otitis Media; Otitis Media with Effusion; Otolaryngology; Participant; Pathogenesis; Prevention; Prevention strategy; Publications; Receptor Signaling; Recurrence; Reporting; Research; Research Personnel; Role; Scientist; Series; Signal Pathway; Time; Toll-like receptors; Translational Research; Vaccines; clinical application; expectation; genetic epidemiology; improved; medical specialties; meetings; multidisciplinary; next generation; novel; pathogen; symposium; vaccine development; vaccinology

DESCRIPTION (provided by applicant): The 2011 10th International Post-Symposium Research Conference in Recent Advances in Otitis Media, to be held on June 9 & 10, in New Orleans, LA, will be the tenth of a series of quadrennial conferences funded by the NIDCD. The purpose of these conferences has been to advance our knowledge and to facilitate progress in biomedical research through the exchange of current findings and advancements related to otitis media (OM), as well as the molecular mechanisms that underlie the etiology of this disorder. OM research is a rapidly expanding field that encompasses a wide variety of disciplines; particularly genetics, microbiology, immunology, molecular biology and vaccinology. Efforts to unravel the role of innate immunity in OM, the function of Toll-like receptors and signaling pathways in pathogenesis, and understand the contribution of bacterial biofilms to the recurrence and chronicity of OM, among others, and which were first presented at the 2004 and 2007 meetings have exploded in recent years, and are producing results that will undoubtedly have an important impact on both translational research and clinical applications. Due to the multidisciplinary nature of the OM research field, these post-symposium research conferences provide a venue for the exchange of vital and current information that will ultimately lead to an enhanced understanding of this disease at the molecular level and also pave the way for the rapid development of novel treatment options and prevention strategies (i.e. vaccines) for OM. Scientific contributions at previous conferences have come from such disciplines as epidemiology, microbiology of OM pathogens, immunology, molecular and cellular pathogenesis, animal models, and vaccine development. The 10th International Symposium on Recent Advances in Otitis Media and its complimentary10th International Post-Symposium Research Conference in Recent Advances in Otitis Media hold great promise for delivering a similar level of interaction among various multidisciplinary groups, as well as for introducing the latest new and emerging areas of research. The hallmark of the previous nine conferences has been their ability to draw together representatives of each of the diverse disciplines and specialties essential to both advancement of the field and to gaining an improved understanding of OM. Another aspect that these conferences have in common is that they continuously attract young investigators from such varied fields as microbiology, molecular and cellular biology, immunology, epidemiology, etc. This is a critical factor when one considers that any expectations in terms of better management and treatment of OM will undoubtedly emerge only through a concerted and multidisciplinary effort. Moreover, continued forward movement of this effort will ultimately become the responsibility of the next generation of clinician and basic scientists.

说明（由申请人提供）： 2011 年第 10 届中耳炎最新进展国际会后研究会议将于 6 月 9 日至 10 日在路易斯安那州新奥尔良举行，这将是由NIDCD。这些会议的目的是通过交流中耳炎 (OM) 相关的最新发现和进展以及该疾病病因的分子机制，增进我们的知识并促进生物医学研究的进展。 OM 研究是一个快速扩展的领域，涵盖了多种学科；特别是遗传学、微生物学、免疫学、分子生物学和疫苗学。努力揭示先天免疫在 OM 中的作用、Toll 样受体的功能和信号通路在发病机制中的作用，并了解细菌生物膜对 OM 复发和慢性化的贡献等，这些工作首次在 2004 年发表2007年和2007年的会议近年来呈爆炸式增长，所产生的成果无疑将对转化研究和临床应用产生重要影响。由于 OM 研究领域的多学科性质，这些会后研究会议提供了交流重要和当前信息的场所，最终将增强对这种疾病在分子水平上的了解，并为未来的研究铺平道路。快速开发 OM 的新治疗方案和预防策略（即疫苗）。往届会议的科学贡献来自流行病学、OM 病原体微生物学、免疫学、分子和细胞发病机制、动物模型和疫苗开发等学科。第十届中耳炎最新进展国际研讨会及其附属的第十届中耳炎最新进展国际会后研究会议有望在各个多学科小组之间提供类似水平的互动，并介绍最新的和正在出现的最新进展研究领域。前九次会议的特点是能够聚集各个不同学科和专业的代表，这对于该领域的进步和加深对 OM 的理解至关重要。这些会议的另一个共同点是，它们不断吸引来自微生物学、分子和细胞生物学、免疫学、流行病学等不同领域的年轻研究人员。当人们认为对更好的管理和管理的任何期望时，这是一个关键因素。毫无疑问，只有通过多学科的共同努力才能治疗 OM。此外，这项工作的持续推进最终将成为下一代临床医生和基础科学家的责任。

项目成果

Panel 1: Epidemiology, natural history, and risk factors.

第 1 组：流行病学、自然史和危险因素。

• 发表时间: 2013-04
• 作者: Hoffman, Howard J;Daly, Kathleen A;Bainbridge, Kathleen E;Casselbrant, Margaretha L;Homoe, Preben;Kvestad, Ellen;Kvaerner, Kari Jorunn;Vernacchio, Louis
• 通讯作者: Vernacchio, Louis

Panel 2: Eustachian tube, middle ear, and mastoid--anatomy, physiology, pathophysiology, and pathogenesis.

第 2 部分：咽鼓管、中耳和乳突——解剖学、生理学、病理生理学和发病机制。

• 发表时间: 2013-04
• 作者: Swarts, J Douglas;Alper, Cuneyt M;Luntz, Michal;Bluestone, Charles D;Doyle, William J;Ghadiali, Samir N;Poe, Dennis S;Takahashi, Haruo;Tideholm, Bo
• 通讯作者: Tideholm, Bo