2011 Epithelial Differentiation & Keratinization

2011 上皮分化

• 批准号: 8119177
• 负责人: RAPHAEL KOPAN
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8119177
• 关键词: Academia; Adhesions; Area; Asia; Authorization documentation; Award; Biology; Cell physiology; Cells; Clinical; Collaborations; Commit; Cytoskeleton; Defect; Dermatologist; Development; Developmental Biology; Disease; Ensure; Environment; Epidermis; Epigenetic Process; Epithelial; Epithelium; Europe; Evolution; Fostering; Functional disorder; Funding; Future; Goals; Hair follicle structure; Health Professional; Homeostasis; Immune system; Immunologist; Immunology; Industry; Inflammation; International; Intestines; Investigation; Minority; Mission; Molecular; Morphogenesis; Natural regeneration; Oral; Participant; Pathologist; Postdoctoral Fellow; Recording of previous events; Regulation; Research; Research Personnel; Resort; Retina; Role; Schedule; Scholarship; Science; Scientist; Senior Scientist; Skin; Snow; Stem cells; Students; Systemic disease; Therapeutic; Travel; Underrepresented Minority; Vermont; Vision; Work; abstracting; appendage; cost; experience; frontier; graduate student; innovation; insight; interest; keratinization; keratinocyte; keratinocyte differentiation; mammary epithelium; meetings; microbiome; novel; novel therapeutic intervention; planetary Atmosphere; posters; programs; regenerative; success; symposium

DESCRIPTION (provided by applicant): The Gordon Research Conference on Epithelial Differentiation and Keratinization has provided the premier forum for presentation and discussion of research in epithelial biology for several decades. This conference is routinely oversubscribed and is attended by the foremost international scientists in epithelial biology, as well as by more junior investigators, postdoctoral fellows, students, and scientists from industry. In recent years, the original focus on epidermal differentiation has broadened to encompass a wide range of topics of interest to epithelial biologists, including developmental biology of the skin and its appendages, stem cells and regenerative processes, epigenetics, the skin microbiome, immunology of the skin, and the role of the epidermal barrier in systemic disease. While the 2009 Conference highlighted hair follicle biology, the 2011 meeting will emphasize the epidermis, as well as covering a range of topics at the forefront of epithelial biology research. We will include scientists working in non-epidermal epithelia such as the retina, mammary epithelium, and intestine, and researchers whose interests lie outside epithelia, to provide additional insights, stimulate innovative approaches, and identify new areas of investigation. The program for 2011 provides a strong emphasis on epidermal barrier function and dysfunction; regulation and therapeutic applications of stem cells; inflammation; and morphogenesis. We will continue and build on our long-standing tradition of defining the most important problems and opportunities at the frontiers of epithelial biology, and facilitating interactions and discussion among scientists working in this area as well as leaders in other scientific areas. We aim to further the development of young investigators entering the field of epithelial biology, and to encourage the involvement of scientists from under-represented minorities. To accomplish these aims, the 2011 Conference will bring together an international cadre of participants including scientists from academia, industry, clinicians and basic researchers, young scientists and senior scientists, dermatologists and pathologists, and cell, developmental and molecular biologists in an atmosphere conducive to the free exchange of ideas. "Young Investigator Awards" will be given to the most promising graduate student and postdoctoral level presenters, and we will offer travel scholarships to outstanding minority applicants. The themes to be developed in the Main Sessions include: 1) Differentiation And Disease In Diverse Epithelia; 2) Epidermal Homeostasis and Barrier Function; 3) Therapeutic Applications Of Skin Cells; 4) the Role Of Immune System In Epithelial Biology and disease; 5) Skin Stem Cells; 6) Epithelial Morphogenesis; 6) Polarity, Adhesion, and the Cytoskeleton; and 7) Novel Regulatory Mechanisms. In addition, an oral Issues Rising session on Wednesday evening will highlight submitted abstracts to ensure that the program reflects exciting new topics that emerge between submission of this application and the meeting. The specific goal of this proposal is to generate funds to support Young Investigator Awards, and the travel, registration and for session chairs and invited speakers.

描述（由申请人提供）：戈登上皮分化和角化研究会议几十年来为上皮生物学研究的展示和讨论提供了首要论坛。这次会议通常报名人数超额，参加者包括上皮生物学领域最重要的国际科学家，以及更多的初级研究人员、博士后研究员、学生和工业界的科学家。近年来，对表皮分化的最初关注已扩大到涵盖上皮生物学家感兴趣的广泛主题，包括皮肤及其附属物的发育生物学、干细胞和再生过程、表观遗传学、皮肤微生物组、皮肤免疫学皮肤，以及表皮屏障在全身疾病中的作用。 2009 年会议重点关注毛囊生物学，而 2011 年会议将重点关注表皮，并涵盖上皮生物学研究前沿的一系列主题。我们将包括从事视网膜、乳腺上皮和肠道等非表皮上皮细胞研究的科学家，以及对上皮细胞以外感兴趣的研究人员，以提供更多见解、激发创新方法并确定新的研究领域。 2011 年计划重点关注表皮屏障功能和功能障碍；干细胞的调节和治疗应用；炎;和形态发生。我们将继续并发扬我们的长期传统，即确定上皮生物学前沿最重要的问题和机遇，并促进该领域科学家以及其他科学领域领导者之间的互动和讨论。我们的目标是进一步培养进入上皮生物学领域的年轻研究人员，并鼓励代表性不足的少数族裔科学家的参与。为了实现这些目标，2011年会议将汇集国际骨干参与者，包括来自学术界、工业界的科学家、临床医生和基础研究人员、年轻科学家和资深科学家、皮肤科医生和病理学家以及细胞、发育和分子生物学家，在一个有利于自由交流思想。 “青年研究者奖”将颁发给最有前途的研究生和博士后水平的演讲者，我们将为优秀的少数族裔申请者提供旅行奖学金。主要会议的主题包括： 1) 不同上皮细胞的分化和疾病； 2）表皮稳态和屏障功能； 3）皮肤细胞的治疗应用； 4) 免疫系统在上皮生物学和疾病中的作用； 5）皮肤干细胞； 6) 上皮形态发生； 6) 极性、粘附和细胞骨架； 7) 新颖的监管机制。此外，周三晚上的口头问题上升会议将重点介绍提交的摘要，以确保该计划反映在提交本申请和会议之间出现的令人兴奋的新主题。该提案的具体目标是筹集资金来支持青年研究者奖以及会议主席和特邀演讲者的旅行、注册和会议费用。