2011 Annual Scientific Meeting of the International Childhood Leukemia Consortium

国际儿童白血病联盟 2011 年度科学会议

• 批准号: 8257462
• 负责人: Patricia A Buffler
• 金额: $ 1万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-15 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8257462
• 关键词: Child; Childhood Leukemia; Classification; Clinical; Commit; Country; Data; Data Analyses; Databases; Development; Dictionary; Disease; Environmental Risk Factor; Epidemiologic Studies; Etiology; Family; Future; Genetic; Goals; Individual; International; Malignant Childhood Neoplasm; Malignant Neoplasms; Online Systems; Persons; Preventive Intervention; Relative (related person); Research; Research Activity; Research Personnel; Resources; Role; System; Techniques; Testing; Trust; Work; base; case control; cohort; data sharing; early life exposure; genetic risk factor; improved; interest; leukemia; meetings; member; novel; public health relevance

DESCRIPTION (provided by applicant) Leukemia is the most commonly occurring cancer among children. Despite improved assessment of parental and early life exposures, the relative rarity of the disease makes the study of the environmental and genetic risk factors challenging. A group of independent, international researchers established the Childhood Leukemia International Consortium (CLIC) to overcome the limitations of individual, smaller studies, and support the study of causal factors in the etiology of childhood leukemia. The annual meetings of the CLIC consortium provide an important opportunity for CLIC investigators, as well as other interested parties, to develop and discuss collaborative analyses and future projects. These annual in person meetings also provide the opportunity to build trust, respect and confidence among researchers from different countries; to provide guidance and advice to researchers planning new studies; and to provide a forum for discussion, development, and pursuit of new research directions. Specifically, the 2011 CLIC Annual Meeting will provide attendees with the opportunities to: 1) Discuss novel scientific hypotheses, cutting edge techniques in genetic studies, methodologic issues in pooled analyses, and other topics of emerging interest, 2) Conduct working sessions for all members pursuing collaborative studies and develop proposals for pooled analyses from international epidemiologic studies of childhood leukemia; 3) Develop needed data dictionaries and classification systems and beta test the new web-based interactive CLIC centralized data repository; and, 4) Coordinate research activities with the childhood leukemia study being conducted by the International Childhood Cancer Cohort Consortium (I4C). Public Health Relevance: Although leukemia is the most frequent cancer occurring among children, its relative rarity makes the study of the environmental and genetic risk factors challenging. The Childhood Leukemia International Consortium (CLIC) consists of a group of independent and international researchers who are committed to pooling resources and data with the ultimate goal of understanding the causes of childhood leukemia and identifying targets for intervention and prevention. The annual meetings of the CLIC consortium provides an opportunity for CLIC investigators, as well as other interested parties, to develop collaborative projects and data analyses; build trust, respect and confidence among researchers from different countries; provide guidance and advice to researchers planning new studies; and provide a forum for discussion, development, and pursuit of new research directions.

描述（由申请人提供） 白血病是儿童中最常见的癌症。尽管对父母和早期生活暴露的评估有所改善，但该疾病的相对罕见性使得环境和遗传风险因素的研究具有挑战性。 一组独立的国际研究人员成立了儿童白血病国际联盟 (CLIC)，以克服个体、小型研究的局限性，并支持儿童白血病病因学中因果因素的研究。 CLIC 联盟的年度会议为 CLIC 研究人员以及其他感兴趣的各方提供了开发和讨论协作分析和未来项目的重要机会。这些年度面对面会议还提供了在不同国家的研究人员之间建立信任、尊重和信心的机会；为规划新研究的研究人员提供指导和建议；并为讨论、发展和追求新的研究方向提供一个论坛。具体来说，2011 年 CLIC 年会将为与会者提供以下机会： 1) 讨论新颖的科学假设、遗传学研究的尖端技术、汇总分析中的方法学问题以及其他新兴兴趣的主题， 2) 为所有从事合作研究的成员举办工作会议，并为儿童白血病国际流行病学研究的汇总分析提出建议； 3) 开发所需的数据词典和分类系统，并对新的基于网络的交互式 CLIC 集中数据存储库进行 Beta 测试；和， 4) 与国际儿童癌症队列联盟 (I4C) 正在进行的儿童白血病研究协调研究活动。 公共健康相关性：尽管白血病是儿童中最常见的癌症，但其相对罕见使得环境和遗传风险因素的研究具有挑战性。儿童白血病国际联盟 (CLIC) 由一群独立的国际研究人员组成，他们致力于汇集资源和数据，最终目标是了解儿童白血病的原因并确定干预和预防的目标。 CLIC联盟的年度会议为CLIC研究人员以及其他感兴趣的各方提供了开发合作项目和数据分析的机会；在不同国家的研究人员之间建立信任、尊重和信心；为规划新研究的研究人员提供指导和建议；并提供一个讨论、发展和追求新研究方向的论坛。