VisualSonics Vevo770 High Resolution In Vivo Imaging System

VisualSonics Vevo770 高分辨率体内成像系统

• 批准号: 7595598
• 负责人: G. Gary Sahagian
• 金额: $ 34.26万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-14 至 2010-05-13
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7595598
• 关键词: Accounting; Advisory Committees; Animals; Applications Grants; Area; Arts; Biology; Biomedical Research; Biophotonics; Blood Vessels; Boston; Cancer Center; Chairperson; Complement; Development; Equipment; Funding; Health Sciences; Housing; Image; Imaging technology; Laboratory Animal Medicine; Maintenance; Medical center; Physiology; Policies; Request for Applications; Research; Research Personnel; Research Support; Resolution; Role; System; Technology; Training; Ultrasonography; United States National Institutes of Health; Universities; base; cancer stem cell; disease diagnosis; experience; fluorescence imaging; in vivo; instrument; medical schools; optical imaging; outcome forecast; public health relevance

DESCRIPTION (provided by applicant): This application requests funds for a VisualSonics Vevo770 Imaging System to support research being carried out at Tufts University School of Medicine (TUSM) and the Tufts Medical Center (TMC) in Boston. A core group of 12 well funded NIH investigators will be the primary users of the instrument and will account for approximately 80% of its use. Cutting edge projects in the areas of cancer, stem cell and vascular biology are described. The system will be housed in the TUSM/TMC Small Animal Imaging Facility where it will complement existing optical imaging equipment including a Xenogen IVIS biophotonic imager and a Leica MZFLIII stereo fluorescence imaging system. Addition of the instrument to the facility is strongly supported by the Chairman of the Department of Physiology, who will provide space for the instrument and administrative support, the Dean of the Medical School who will provide support for an experienced sonographer, and the Vice President of Research at the Medical Center, who will provide funds for maintenance of the instrument. The Facility is directed by the PI and the instrument will be managed and operated on a day-to-day basis by the Facility Manager and a Sonographer who will also train new users. Several investigators at TUSM/TMC have expertise in ultrasound technology including Dr. Richard Patten, who will serve as an onsite consultant for the instrument. An advisory committee consisting of the PI (TUSM), Dr. Patten (TMC) and representatives from the TMC Cancer Center, the Division of Laboratory Animal Medicine, and the Medical School's Department of Physiology will oversee use of the Vevo770 system and develop policies for use and equitable sharing of the instrument. The availability of the Vevo770 imaging system will greatly enhance the quality and extent of NIH- funded biomedical research being carried out on the Tufts Health Sciences Campus in Boston. PUBLIC HEALTH RELEVANCE: If funded, this grant proposal will result in the purchase of a state-of-the-art ultrasound imaging system that will accelerate cutting edge NIH-funded research being conducted at Tufts Medical School and Medical Center. Funding of the proposal will also contribute to the development of new imaging technology that is expected by many to have an increasingly important role in disease diagnosis, prognosis and treatment.

描述（由申请人提供）：本申请要求为 VisualSonics Vevo770 成像系统提供资金，以支持塔夫茨大学医学院 (TUSM) 和波士顿塔夫茨医学中心 (TMC) 正在进行的研究。由 12 名资金充足的 NIH 研究人员组成的核心小组将成为该仪器的主要用户，并将占其使用量的约 80%。描述了癌症、干细胞和血管生物学领域的前沿项目。该系统将安装在 TUSM/TMC 小动物成像设施中，补充现有的光学成像设备，包括 Xenogen IVIS 生物光子成像仪和 Leica MZFLIII 立体荧光成像系统。在该设施中添加该仪器得到了生理学系主任的大力支持，他将为仪器提供空间和行政支持，医学院院长将为经验丰富的超声技师提供支持，以及副校长医疗中心的研究，谁将提供仪器维护的资金。该设施由 PI 指导，仪器将由设施经理和超声技师进行日常管理和操作，超声技师还将培训新用户。 TUSM/TMC 的几位研究人员拥有超声技术方面的专业知识，其中包括 Richard Patten 博士，他将担任该仪器的现场顾问。由 PI (TUSM)、Patten 博士 (TMC) 以及来自 TMC 癌症中心、实验动物医学部门和医学院生理学系的代表组成的咨询委员会将监督 Vevo770 系统的使用并制定政策使用和公平分享该工具。 Vevo770 成像系统的可用性将大大提高 NIH 资助的在波士顿塔夫茨健康科学园区进行的生物医学研究的质量和范围。公共健康相关性：如果获得资助，这项拨款提案将导致购买最先进的超声成像系统，这将加速塔夫茨医学院和医疗中心正在进行的由 NIH 资助的尖端研究。该提案的资助还将有助于新成像技术的发展，许多人预计该技术将在疾病诊断、预后和治疗中发挥越来越重要的作用。