Integrative Treatment for Achieving Holistic Recovery from Comorbid Chronic Pain and Opioid Use Disorder

实现慢性疼痛和阿片类药物使用障碍共病的整体康复的综合治疗

基本信息

批准号：
10876694
负责人：
Matthew Ryan Pearson
金额：
$ 203.31万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-30 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10876694
关键词：
Integrative Treatment Achieving Holistic Recovery

项目摘要

PROJECT SUMMARY Chronic pain and opioid use disorder (OUD) are major public health problems. Despite the alarming increases in opioid misuse and OUD, few integrated treatments target both chronic pain and OUD. Integrated holistic treatments are desperately needed that simultaneously address pain and opioid use, the fundamental causes of pain and OUD, and that focus on whole person functioning and well-being among individuals with chronic pain and opioid misuse/OUD. The University of New Mexico (UNM) Integrative Management of chronic Pain and Opioid use disorder for Whole Recovery (IMPOWR) Center will take an integrated and holistic approach to improving the lives of patients with chronic pain and opioid misuse/OUD via tailored intervention approaches to meet the needs of diverse individuals in diverse communities. We will explicitly target increasing quality of life and engagement in valued activities, the cultural centering of interventions to meet the needs of diverse patient populations, and reducing stigma of chronic pain and opioid misuse and OUD. The approaches proposed in our IMPOWR Center will directly target whole person functioning and well-being among individuals with chronic pain and misuse/OUD. Our goals are to develop, test, and implement scalable, generalizable, and sustainable provider- and patient-level interventions that are focused on improving functioning and can be delivered in diverse health care settings. To maximize impact, we have established a diverse Stakeholder Consultation Board (including people with lived experience and other stakeholders) and a Scientific Advisory Board (including experts in chronic pain, opioid misuse/OUD, and implementation science), and aim to build a sustainable workforce of researchers and providers devoted to ameliorating chronic pain and OUD via training and mentoring. All Center projects will embrace principles of community-based participatory research, team science, implementation science, economic evaluation, and open science. Consistent with our patient-centered approach, assessment of opioid use and chronic pain will be complemented with measures of psychosocial functioning and other important life domains, including stigma, engagement in valued activities, and quality of life. Projects will include economic evaluation to measure cost-effectiveness of our interventions from a societal perspective. Specific research projects will test the effectiveness, mechanisms, and implementation of an integrated psychosocial treatment for chronic pain and OUD among individuals receiving buprenorphine from outpatient OUD treatment clinics, and will use community-based participatory research methods to develop a culturally-centered implementation intervention for screening and brief intervention of chronic pain and OUD among American Indian/Alaska Native patients in primary care settings. Pilot projects focused on chronic pain and OUD will be selected by our Stakeholder Consultation Board. The UNM IMPOWR Center is committed to data harmonization, sharing of study resources, and provider training to enhance the reach, effectiveness, adoption, implementation, and maintenance of evidence-based treatments for chronic pain and OUD.

项目概要慢性疼痛和阿片类药物使用障碍（OUD）是主要的公共卫生问题。尽管增幅惊人在阿片类药物滥用和 OUD 中，很少有综合治疗能够同时针对慢性疼痛和 OUD。综合整体迫切需要同时解决疼痛和阿片类药物使用的治疗方法，这是根本原因疼痛和 OUD，重点关注慢性病患者的整个人的功能和福祉疼痛和阿片类药物滥用/OUD。新墨西哥大学 (UNM) 慢性疼痛综合管理阿片类药物使用障碍整体康复 (IMPOWR) 中心将采取综合和整体方法通过量身定制的干预方法改善慢性疼痛和阿片类药物滥用/OUD 患者的生活满足不同社区中不同个人的需求。我们将明确以提高生活质量为目标参与有价值的活动，干预措施以文化为中心，以满足不同患者的需求人口，并减少慢性疼痛和阿片类药物滥用和 OUD 的耻辱。中提出的方法我们的 IMPOWR 中心将直接针对慢性病患者的整体功能和福祉痛苦和误用/OUD。我们的目标是开发、测试和实施可扩展、通用和可持续的提供者和患者层面的干预措施侧重于改善功能，并且可以在多样化的医疗保健环境。为了最大限度地发挥影响力，我们建立了多元化的利益相关者磋商机制委员会（包括有生活经验的人和其他利益相关者）和科学顾问委员会（包括慢性疼痛、阿片类药物滥用/OUD 和实施科学方面的专家），并旨在建立一个由研究人员和提供者组成的可持续劳动力队伍致力于通过培训改善慢性疼痛和 OUD 和指导。所有中心项目都将遵循基于社区的参与性研究、团队的原则科学、实施科学、经济评估和开放科学。符合我们以患者为中心的理念方法，对阿片类药物使用和慢性疼痛的评估将辅以心理社会措施功能和其他重要的生活领域，包括耻辱、参与有价值的活动以及生活质量生活。项目将包括经济评估，以衡量我们的社会干预措施的成本效益看法。具体研究项目将检验该计划的有效性、机制和实施情况。对接受丁丙诺啡的个体进行慢性疼痛和 OUD 的综合心理社会治疗门诊 OUD 治疗诊所，并将使用基于社区的参与性研究方法来开发以文化为中心的实施干预，用于慢性疼痛和 OUD 的筛查和简短干预初级保健机构中的美洲印第安人/阿拉斯加原住民患者。专注于慢性疼痛的试点项目 OUD 将由我们的利益相关者咨询委员会选出。新墨西哥州 IMPOWR 中心致力于数据协调、研究资源共享以及提供者培训，以提高覆盖范围、有效性、采用、实施和维持慢性疼痛和 OUD 的循证治疗方法。