Integrative Treatment for Achieving Holistic Recovery from Comorbid Chronic Pain and Opioid Use Disorder

实现慢性疼痛和阿片类药物使用障碍共病的整体康复的综合治疗

基本信息

批准号：
10622257
负责人：
Matthew Ryan Pearson
金额：
$ 21.25万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-30 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10622257
关键词：
Alaska Native American Indians Applications Grants Area Benchmarking Clinic Cognitive Communities Data Data Analyses Development Ecological momentary assessment Effectiveness Enrollment Exposure to Frequencies Funding Future Goals Grant Hispanic Hispanic Populations Individual Integrative Therapy Intervention Interview Latino Latino Population Manuscripts Mentors Methods Native Americans New Mexico Pain Participant Persons Phase Primary Health Care Principal Investigator Process Production Program Development Protocols documentation Qualitative Research Quality Control Recovery Reporting Research Research Methodology Research Personnel Research Project Grants Site Time Training United States United States National Institutes of Health Universities Writing acceptability and feasibility adaptive intervention base biopsychosocial factor chronic pain chronic pain management community based participatory research comorbidity craving disorder later incidence prevention distress tolerance economic evaluation effectiveness implementation trial experience high risk holistic approach implementation science improved innovative technologies interest mHealth mindfulness motivational enhancement therapy opioid misuse opioid use disorder parent grant phase 1 study phase 2 study posters preventive intervention psychosocial research data dissemination responsible research conduct satisfaction symposium

项目摘要

Project Summary The Parent Grant, the UNM IMPOWR Center (University of New Mexico Integrative Management of chronic Pain and Opioid use disorder for Whole Recovery; RM1DA055301; mPIs Witkiewitz, Pearson), seeks to utilize a holistic approach to assess and treat biopsychosocial factors that contribute to pain and opioid use disorder (OUD), and improve the lives of diverse individuals with chronic pain and opioid misuse/OUD in diverse communities. UNM IMPOWR has two major research projects. The HOPE Trial is a multisite effectiveness- implementation trial investigating the effectiveness of an integrated treatment for chronic pain and OUD (Acceptance and Commitment Therapy [ACT] and Mindfulness-Based Relapse Prevention [MBRP]). The OPTIC Trial uses community-based participatory research (CBPR) methods to develop a culturally centered intervention for chronic pain and OUD in American Indian/Alaska Native primary care clinics based on Native American Motivational Interviewing. UNM IMPOWR has also convened a community advisory board and scientific advisory board to help guide program development, implementation, and to maximize research impact. The research aims of the diversity supplement are to 1) begin the process to culturally center two integrated treatments for chronic pain and opioid use disorder (Acceptance and Commitment Therapy and Mindfulness-Based Relapse Prevention) for Hispanic/Latino/a/x individuals in the United States; 2) examine acceptability, feasibility, and compliance rates of an ecological momentary assessment study of pain, cognitive defusion, craving, mindfulness, and distress tolerance ; and 3) evaluate the degree of within- and between- subject variability in constructs of interest including pain, cognitive defusion, craving, mindfulness, and distress tolerance. The training aims of the supplement are to 1) acquire training in community-based participatory research; 2) acquire training in psychosocial treatments for opioid use disorder; 3) obtain experience in advanced quantitative approaches for longitudinal and intensive longitudinal data; 4) receive training in qualitative research methods and qualitative data analysis; and 5) receive training in manuscript production, research dissemination (e.g., posters, symposia), writing NIH grant applications, and the responsible conduct of research. Ultimately, the overall training and research experiences will prepare Dr. Schwebel to become a successful independent researcher examining chronic pain and OUD.

项目概要家长补助金，UNM IMPOWR 中心（新墨西哥大学慢性病综合管理疼痛和阿片类药物使用障碍的整体康复； RM1DA055301； mPI Witkiewitz、Pearson），力求利用评估和治疗导致疼痛和阿片类药物使用障碍的生物心理社会因素的整体方法 (OUD)，并改善患有慢性疼痛和阿片类药物滥用/OUD 的不同个体的生活社区。 UNM IMPOWR 有两个主要研究项目。 HOPE 试验是一项多站点有效性试验 - 实施试验调查慢性疼痛和 OUD 综合治疗的有效性（接受和承诺疗法 [ACT] 和基于正念的复发预防 [MBRP]）。这 OPTIC 试验使用基于社区的参与性研究 (CBPR) 方法来开发以文化为中心的研究基于 Native 的美洲印第安人/阿拉斯加原住民初级保健诊所的慢性疼痛和 OUD 干预美国励志访谈。 UNM IMPOWR 还召集了一个社区咨询委员会并科学顾问委员会帮助指导项目的开发、实施并最大限度地发挥研究作用影响。多样性补充的研究目标是 1）开始以文化为中心的过程慢性疼痛和阿片类药物使用障碍的综合治疗（接受和承诺疗法和基于正念的复发预防）针对美国的西班牙裔/拉丁裔/a/x 人群； 2）检查疼痛、认知的生态瞬时评估研究的可接受性、可行性和依从率解脱、贪爱、正念和苦恼忍耐； 3）评估内部和之间的程度兴趣结构的主体变异性，包括疼痛、认知解离、渴望、正念和痛苦宽容。该补充材料的培训目标是 1) 获得基于社区的参与性培训研究; 2) 接受阿片类药物使用障碍心理社会治疗培训； 3) 获得经验纵向和密集纵向数据的先进定量方法； 4）接受培训定性研究方法和定性数据分析； 5) 接受稿件制作培训，研究传播（例如海报、研讨会）、撰写 NIH 拨款申请以及负责任的行为研究。最终，整体培训和研究经验将使施韦贝尔博士成为一名成功的独立研究人员检查慢性疼痛和 OUD。