Medical Scientist Training Program

医学科学家培训计划

• 批准号: 10625664
• 负责人: Myles H. Akabas
• 金额: $ 185.77万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10625664
• 关键词: Medical; Scientist; Training Programs

PROJECT SUMMARY The mission of the Albert Einstein College of Medicine Medical Scientist Training Program (MSTP) is to train physician-scientists who will become leaders in biomedical research to understand, detect, treat, and prevent human disease. To accomplish this mission, we have three goals, 1) to recruit a diverse group of students with outstanding potential to become research-active physician-scientists, 2) to provide training in an inclusive, safe, and stimulating learning environment where students can acquire the foundational knowledge and the technical, operational, and professional skills necessary to pursue a career as a research-active physician- scientist and a leader in academic medicine and/or biomedical research, and 3) to support/facilitate their professional development to transition to the next stage in the training continuum. Through a holistic admissions process, we seek to identify individuals with the intelligence, curiosity, creativity, resilience, perseverence, and enthusiam for science that is essential for a successful research career. We guide the students through a program tailored to meet their individual needs and interests. The program provides rigorous, integrated medical and research training through a flexible, continously evolving curriculum that includes 1) specialized MSTP courses, and 2) integration of graduate and medical school curriculum in the first 2 years and throughout the program. The training program has 3 phases. In the first 2 years students take a combination of medical, graduate, and MSTP-specific courses to gain the didactic foundation for their reseach and clinical training. Research rotations and guidance from program leadership assist them in thesis lab selection. In the program’s 2nd phase, students perform independent, original research under their mentor’s guidance. They publish their discoveries in high quality, peer-reviewed papers, and prepare and defend a PhD thesis. Participation in a PhD phase MSTP-run, outpatient clinic builds clinical skills. In the final phase, they complete their clinical training. A multifaceted approach trains students to perform rigorous and reproducible research in a responsible, ethical manner. Currently, the program has 113 trainees, 41% woman, 28% from groups underrepresented in medicine (twice percentage in the applicant pool), and 11% with disabilities. We will expand to ~120-130 trainees by increasing the entering class size to 16. Since its inception in 1964, as one of the first three NIH-funded MSTPs, 484 trainees have graduated. 413 have completed postgraduate training and published over 19,000 papers, an average of ~47 papers/graduate. 74% have jobs at academic medical centers, research institutes, NIH or pharmaceutical companies. By various measures, the graduates have achieved outstanding success and advanced biomedical research and academic medicine. We propose to further integrate graduate and medical training, and increase opportunities for involvement in clinical and translational research to prepare a future generation of physician-scientists who will be at the leading edge of biomedical research with the ultimate goal of improving human health and reducing the burden of disease.

项目概要 阿尔伯特·爱因斯坦医学院医学科学家培训计划 (MSTP) 的使命是培训 将成为理解、检测、治疗和预防的生物医学研究领导者的医生科学家 为了完成这一使命，我们有三个目标，1）招收具有不同背景的学生。 成为积极研究的医师科学家的杰出潜力，2）提供包容性、 安全、刺激的学习环境，让学生可以获得基础知识和 从事研究活动的医生所必需的技术、操作和专业技能 科学家和学术医学和/或生物医学研究的领导者，以及 3) 支持/促进他们 通过整体培训过渡到下一阶段的专业发展。 招生过程中，我们寻求识别具有智力、好奇心、创造力、适应力、 坚持不懈和对科学的热情对于成功的研究事业至关重要。 学生通过该计划提供的量身定制的计划来满足他们的个人需求和兴趣。 通过灵活、不断发展的课程进行严格、综合的医学和研究培训 包括 1) 专门的 MSTP 课程，以及 2) 研究生和医学院课程的整合 整个课程为期 2 年，分为 3 个阶段。 结合医学、研究生和 MSTP 特定课程，为其研究奠定教学基础 和临床培训。研究轮换和项目领导的指导为他们在论文实验室提供帮助。 在该项目的第二阶段，学生在导师的指导下进行独立的、原创的研究。 他们以高质量的同行评审论文发表他们的发现，并准备和捍卫博士学位。 参与 MSTP 运营的博士阶段门诊，培养临床技能。 多方面的方法训练学生完成严格且可重复的临床培训。 目前，该项目有 113 名学员，其中 41% 为女性，28% 为男性。 医学领域代表性不足的群体（申请人群体中所占比例的两倍），以及 11% 的残疾人。 通过将入学班级人数增加到 16 人，学员将扩大到约 120-130 名学员。自 1964 年成立以来，作为 在 NIH 资助的前三个 MSTP 中，已有 484 名学员毕业，其中 413 名已完成研究生培训。 发表了 19,000 多篇论文，平均每名毕业生约 47 篇论文，74% 的人从事学术医学工作。 通过各种措施，毕业生已在研究中心、研究所、NIH 或制药公司工作。 取得了杰出的成功和先进的生物医学研究和学术医学。 进一步整合研究生和医学培训，增加参与临床和临床工作的机会 转化研究为下一代医学科学家做好准备，他们将处于医学前沿 生物医学研究的最终目标是改善人类健康并减轻疾病负担。