Hermanos de Luna y Sol: A community-based HIV prevention intervention

Hermanos de Luna y Sol：基于社区的艾滋病毒预防干预措施

基本信息

批准号：
10626689
负责人：
Jesus Ramirez-Valles
金额：
$ 71.84万
依托单位：
SAN FRANCISCO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10626689
关键词：
AIDS prevention Acquired Immunodeficiency Syndrome Address Affect Area Awareness Behavioral Biomedical Research Bisexual Buffers Centers for Disease Control and Prevention (U.S.)Chicago Cities Collaborations Communities Community Health Country Diagnosis Discrimination Effectiveness of Interventions Equation Ethnic Origin Evidence based intervention Face Fostering Gays Goals Government HIV HIV Infections HIV diagnosis HIV disparities HIV risk Health Heart Hispanic-serving Institution Homophobia Human Resources Human immunodeficiency virus test Immigrant Incidence Individual Inequity Informal Social Control Interdisciplinary Study Intervention Intervention Studies Language Latin American Latino Latino Population Latinx Latinx population Lead Location Minority-Serving Institution Modeling National Institute of Mental Health National Institute on Minority Health and Health Disparities Observational Study Participant Patient Recruitments Persons Population Prevalence Quasi-experiment Race Racial Equity Randomized Research Risk Risk Behaviors Sampling Sampling Biases Self Perception Sexual Health Shapes Social isolation Social support Testing Time Translations United States United States National Institutes of Health Unsafe Sex Use Effectiveness Woman base bilingualism community building community involvement community organizations contextual factors design distrust effective intervention effectiveness evaluation ethnic minority population experience group intervention health disparity health equity health inequalities improved infection rate innovation insight male marginalized community marginalized population member men men who have sex with men migration multidisciplinary novel pedagogy pre-exposure prophylaxis prevent preventive intervention prospective psychological distress public health priorities public health relevance queer racism recruit self esteem sexual minority group sexual risk behavior social social culture social epidemiology sociocultural determinant therapy design time use uptake volunteer

项目摘要

Abstract The overall goal of our research is to reduce HIV-related health inequities among Latinx immigrant populations. We propose to determine the effectiveness of Hermanos de Luna y Sol (HLS), a community-based, group intervention delivered in Spanish, designed to reduce HIV sexual risk among Latinx immigrants who identify as gay/bisexual men or men who have sex with men (GBMSM). The study is designed as a quasi-experimental, community control, with Oakland, CA as the intervention group and Chicago, IL as the control. Assessments will be conducted at -3 and 0 mos., and follow-ups at 3, 6, and 12 mos. Participants (N=360; n=180 per city) will be recruited using Time-location sampling (a venue-based sampling designed to reduce sample bias). HLS, the intervention at the heart of this study, offers several novel features: it focuses on immigrant, Spanish- speaking populations; it addresses racism and homophobia as factors shaping HIV risk; and uses a community-based approach centered on community involvement (e.g., civic participation, volunteering) as a means to foster sexual health and community building. The study will help identify effective interventions to prevent HIV among Latinx immigrant GBMSM, a marginalized population for which HIV preventive interventions are severely lacking. This study capitalizes on an existing intervention designed for Spanish speaking populations; is the first of its kind to rigorously test the intervention’s effectiveness among Latinx immigrant GBMSM using a community control design. The study applies the best possible scientific approach to obtain estimates of intervention effectiveness. If successful, the intervention would be relatively easy to disseminate via community organizations and the Centers for Disease Control and Prevention. Ultimately, the study will help move forward efforts to reduce racial/ethnic health inequities, one of the nation’s major public health priorities. This proposal is directly relevant to the RFA on Transformative Research to Address Health Disparities and Advance Health Equity at Minority serving Institutions. The project is led by SFSU – a Hispanic Serving Institution-- in collaboration with two Latinx community-based organizations: La Familia and Chicago Queer Latinx Collaborative. We are a multidisciplinary research team with the depth and breadth of experience on HIV prevention with Latinx and GBMSM communities to successfully conduct the study. All senior personnel are of Latin American descent, fully bilingual (Spanish and English), and three of them are women. The proposed study is strongly aligned with NIH UNITED Initiative of fostering racial equity and inclusion in biomedical research and is responsive to priority areas of multiple NIH institutes and centers, such NIMHD, NIMH, and the Office of AIDS Research.

抽象的我们研究的总体目标是减少拉丁裔移民人群中与艾滋病毒相关的健康不平等。我们建议确定 Hermanos de Luna y Sol (HLS) 的有效性，这是一个基于社区的团体以西班牙语提供的干预措施，旨在降低拉丁裔移民的艾滋病毒性风险同性恋/双性恋男性或男男性行为者 (GBMSM) 该研究被设计为一项准实验性的、社区控制，以加利福尼亚州奥克兰为干预组，以伊利诺伊州芝加哥为对照评估。将在 -3 个月和 0 个月进行，并在第 3、6 和 12 个月进行随访参与者（N=360；每个城市 n=180）。将使用时间-地点抽样（旨在减少样本偏差的基于地点的抽样）进行招募。 HLS 是本研究的核心干预措施，具有几个新颖的特点：它重点关注移民、西班牙人它解决了种族主义和恐同症作为影响艾滋病毒风险的因素；以社区参与（例如公民参与、志愿服务）为中心的基于社区的方法意味着促进性健康和社区建设。该研究将有助于确定有效的干预措施，以预防拉丁裔移民 GBMSM 中的艾滋病毒。这项研究利用了严重缺乏艾滋病毒预防干预措施的人口不断减少的情况。为西班牙语人群设计的现有干预措施是同类中第一个严格测试的干预措施；使用社区控制设计对拉丁裔移民 GBMSM 进行干预的有效性。采用尽可能最佳的科学方法来估计干预效果。通过社区组织和疾病中心传播干预措施相对容易最终，该研究将有助于推进减少种族/民族健康的努力。不平等问题是国家主要公共卫生优先事项之一。该提案与 RFA 关于解决健康差异的变革性研究直接相关促进少数族裔服务机构的健康公平该项目由西班牙裔服务机构 SFSU 领导。机构——与两个拉丁裔社区组织合作：La Familia 和 Chicago Queer Latinx Collaborative 是一个多学科研究团队，在相关领域拥有丰富的经验。拉丁裔和 GBMSM 社区的艾滋病毒预防工作成功开展了这项研究。都是拉丁美洲血统，完全双语（西班牙语和英语），其中三人是女性。拟议的研究与 NIH UNITED 促进种族平等和包容性的倡议高度一致生物医学研究，并响应多个 NIH 研究所和中心的优先领域，例如 NIMHD、 NIMH 和艾滋病研究办公室。