Core A - Administrative Core

核心 A - 行政核心

• 批准号: 10907138
• 负责人: Christopher Mark Norris
• 金额: $ 38.08万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10907138
• 关键词: Advisory Committees; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Animals; Astrocytes; Behavioral; Breeding; Budgets; Collaborations; Electrophysiology (science); Endowment; Ensure; Faculty; Feedback; Fostering; Functional disorder; Funding; Future; Genotype; Health; IACUC; Infrastructure; Leadership; Learning; Maintenance; Memory; Neurons; Nutritional Science; Pharmacology; Production; Progress Reports; Protocols documentation; Reagent; Recombinants; Research; Research Personnel; Resources; Role; Route; Science; Services; Signal Transduction; Source; United States National Institutes of Health; Universities; University adminstration; Update; Viral; Work; animal colony; cohesion; data sharing; meetings; mouse model; professor; success; symposium; vascular cognitive impairment and dementia; welfare

CORE A – ABSTRACT SUMMARY The role of Core A (Administrative) is to provide leadership, promote cohesion, and ensure fiscal oversight for the P01 Strategies for Targeting Reactive Astrocytes in AD and ADRD. En route to stimulating and fostering interactions among the P01 team, Core A will provide common resources, manage budgetary issues, and fulfill administrative obligations to the University and to the NIH/NIA. These services will allow the Projects and Cores of the P01 to focus on the Science and reconceptualize the role of reactive astrocytes in the pathophysiology of Alzheimer’s disease (AD) and related dementias (ADRDs). The Aims of Core A are: (1) Provide coordinated and coherent infrastructure that enhances scientific activities. (2) Oversee animal colonies and production/characterization of AAV reagents. And (3) provide fiscal management and administrative support. The Administrative Core will facilitate timely and consistent oversight so that Projects and Cores can work together as a unit to study reactive astrocyte signaling in ADRDs.

核心 A——摘要 核心 A（行政）的作用是提供领导、促进凝聚力并确保财政监督 P01 针对 AD 和 ADRD 中反应性星形胶质细胞的策略，以刺激和培养。 P01 团队之间的互动，核心 A 将提供公共资源、管理预算问题并履行 对大学和 NIH/NIA 的行政义务这些服务将允许项目和核心。 P01 的重点是科学并重新概念化反应性星形胶质细胞在病理生理学中的作用 核心 A 的目标是：(1) 提供协调一致的治疗。 和加强科学活动的连贯基础设施 (2) 监督动物群体和 AAV 试剂的生产/表征；以及 (3) 提供财政管理和行政支持。 行政核心将促进及时和一致的监督，以便项目和核心能够发挥作用 作为一个单元来研究 ADRD 中的反应性星形胶质细胞信号传导。