Cancer Prevention and Control Research Program

癌症预防与控制研究计划

• 批准号: 10627509
• 负责人: Timothy L. Lash
• 金额: $ 5.44万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-07 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627509
• 关键词: Adherence; Adolescent; Affect; American Cancer Society; Area; Award; Behavior Therapy; Behavioral; Behavioral Sciences; Biological; Biological Markers; Biometry; Brain; Cancer Burden; Cancer Center Support Grant; Cancer Control; Cancer Control Research Program; Cancer Etiology; Cancer Patient; Cancer Survivor; Cancer Survivorship; Cardiovascular Diseases; Caring; Catchment Area; Centers for Disease Control and Prevention (U.S.); Childhood; Collaborations; Communities; Community Outreach; DNA; Data; Discipline; Discipline of Nursing; Disparity; Economics; Environment; Environmental Exposure; Epidemiology; Exposure to; Funding; Goals; Health; Healthcare; Human Papilloma Virus Vaccination; Individual; Inequity; International; Intervention; Journals; Knowledge; Late Effects; Leadership; Malignant Neoplasms; Medicine; Mission; Oncology; Outcome; Patient Outcomes Assessments; Peer Review; Policies; Population; Population Research; Prevention Research; Primary Care; Public Health; Public Health Schools; Publishing; Quality of Care; Quality of life; Recurrence; Research; Research Activity; Research Personnel; Research Training; Resource Sharing; Risk Factors; Risk Reduction; Rural; School Nursing; Scientist; Societies; Soot; Strategic Planning; Survivors; Symptoms; System; Technology; Underrepresented Populations; Universities; Weight Gain; biobehavior; burden of illness; cancer care; cancer diagnosis; cancer epidemiology; cancer prevention; cancer risk; career; community engaged research; community engagement; health equity; health organization; human disease; improved; innovation; learning community; medical schools; member; neoplasm registry; next generation; prevent; programs; recruit; reduce tobacco use; social; success; survivorship; symptom management; therapy development; tobacco control; vaccine acceptance; ward; weight gain prevention

PROJECT SUMMARY/ABSTRACT CANCER PREVENTION AND CONTROL PROGRAM The Cancer Prevention and Control (CPC) Program of Winship Cancer Institute of Emory University (Winship) coordinates and promotes all cancer prevention and control-related research activities within the center. The goal of CPC Program is to generate knowledge through innovative research and learning from the community, that will transform cancer prevention and care and reduce the cancer burden in Winship’s catchment area, the state of Georgia, and beyond. CPC has four scientific themes: (1) Cancer Epidemiology - to achieve high quality surveillance of the cancer burden and identify risk factors such as biological, behavioral, social and policy factors, and environmental exposures, to inform targeted interventions and strategies to reduce cancer risk in Georgia; (2) Interventions - focus on HPV vaccination uptake, individual behavioral interventions to reduce tobacco use and to prevent weight gain, and policy and systems-level changes with the ultimate goal of broad-scale implementation of effective strategies; (3) Cancer Survivorship and Symptom Management - focus on treatment- related early effects, including patient-reported outcomes, biobehavioral changes in the brain, childhood and adolescent cancer survivors transition to primary care, and late effects such as cardiovascular disease, which substantially affect the quality-of-life of cancer patients and survivors; and (4) Quality of Cancer Care - to conduct population-based research that describes, interprets, and predicts the impact of health care interventions and other factors on adherence to care, quality of cancer care, inequities in care, and outcomes. Under the leadership of Timothy L. Lash, DSc, MPH (leader) and Mylin Torres, MD (co-leader), CPC includes 53 core members representing 16 different departments within the School of Medicine, Nell Hodgson Woodruff School of Nursing, and Rollins School of Public Health at Emory University. This diverse membership furnishes a rich research training environment for the next generation of cancer researchers. CPC engages in ongoing interactions with Community Outreach and Engagement (COE) to inform research on catchment area priorities and actively engages in promoting biomedical scientific careers for under-represented groups. This highly collaborative group of researchers published 1,074 cancer-relevant scientific articles during the current funding period. Of these, 275 (26%) were intra- and 290 (27%) were inter-programmatic collaborations and 779 (73%) represented a collaboration with an external academic organization. 144 (13%) were published in journals with an impact factor of ≥ 10. As of end of 2021, CPC members held $14.5 million in annual total cancer-relevant research funding, of which $11.3 million is peer-reviewed (78%) and $8.6 million (59%) was awarded directly from NCI. Funding from NCI increased from $4.4 million in 2016 to $8.6 million in 2021. Notable new funding includes an R01 to support the addition of recurrence surveillance to the Georgia Cancer Registry ($3.7M total, R01CA234538, Ward/Lash), and renewed Centers for Disease Control and Prevention (CDC) funding of the Emory Prevention Research Center (U48DP006377, Kegler), focused on cancer prevention in rural Georgia.

项目概要/摘要 癌症预防和控制计划 埃默里大学温希普癌症研究所癌症预防与控制（CPC）项目（Winship） 协调和促进中心内所有与癌症预防和控制相关的研究活动。 CPC 计划的目标是通过创新研究和向社区学习来产生知识， 这将改变癌症预防和护理并减少温希普学区的癌症负担 乔治亚州及其他地区的 CPC 有四个科学主题： (1) 癌症流行病学 - 实现高质量。 监测癌症负担并确定生物、行为、社会和政策因素等风险因素， 和环境暴露，为降低格鲁吉亚癌症风险的有针对性的干预措施和战略提供信息； (2) 干预措施——重点关注 HPV 疫苗接种、个人行为干预以减少烟草使用 并防止体重增加以及政策和系统层面的变化，最终目标是大规模 实施有效的策略；（3）癌症生存和症状管理——关注治疗—— 相关的早期影响，包括患者报告的结果、大脑、儿童和儿童的生物行为变化 青少年癌症幸存者过渡到初级保健，以及心血管疾病等后期影响，这 (4) 癌症护理质量 - 进行 以人群为基础的研究，描述、解释和预测医疗保健干预措施的影响 影响护理依从性、癌症护理质量、护理不平等和结果的其他因素。 由 Timothy L. Lash, DSc, MPH（领导者）和 Mylin Torres, MD（联合领导者）组成，CPC 包括 53 名核心成员 代表医学院、内尔·霍奇森·伍德拉夫护理学院的 16 个不同院系， 埃默里大学罗林斯公共卫生学院的多元化成员提供了丰富的研究。 为下一代癌症研究人员提供持续互动的培训环境。 社区外展和参与 (COE) 为流域优先事项的研究提供信息并积极 这个高度协作的团体致力于促进代表性不足的群体的生物医学科学事业。 的研究人员在当前资助期间发表了 1,074 篇与癌症相关的科学文章，其中 275 篇。 (26%) 属于项目内合作，290 项 (27%) 属于项目间合作，779 项 (73%) 属于项目间合作 与外部学术组织合作的论文有 144 篇（13%）在有影响力的期刊上发表。 因子≥10。截至2021年底，CPC成员每年的癌症相关研究总额为1450万美元 资金，其中 1130 万美元经过同行评审（78%），860 万美元（59%）由 NCI 直接资助。 NCI 的资金从 2016 年的 440 万美元增加到 2021 年的 860 万美元。值得注意的新资金包括 R01 支持在佐治亚州癌症登记处增加复发监测（总计 370 万美元， R01CA234538，病房/拉什），并更新了疾病控制和预防中心 (CDC) 的资助 埃默里预防研究中心（U48DP006377，Kegler），专注于佐治亚州农村地区的癌症预防。