The Institute for Translational Medicine

转化医学研究所

基本信息

批准号：
10632295
负责人：
Joshua J Jacobs
金额：
$ 829.87万
依托单位：
UNIVERSITY OF CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-06 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10632295
关键词：
Accounting Address Advocacy Advocate Alcohols Awareness Behavior Therapy Behavioral Biological Caring Chicago Clinical Research Clinical Sciences Communication Communities Disease Economics Education Employment Engineering Ensure Environment Ethics Ethnic Origin Exposure to Food Gender Goals Government Agencies Health Health Personnel Health Status Health system Healthcare Hearing Home Housing Human Biology Illinois Immigration Impaired health Individual Infrastructure Injury Institutes Institution Intervention Investments Knowledge Laws Leadership Letters Life Experience Medical Medicine Morbidity - disease rate Pharmaceutical Preparations Physical environment Policies Poverty Psychological Factors Public Health Race Regulation Reporting Research Research Personnel Research Training Resources Role Safety Schools Science Scientist Seminal Services Sex Behavior Sex Orientation Smoking Social Environment Social Sciences Social Work Societies Special Population Stream Structural Racism System Tail Technology Testing Training Translational Research Transportation United States National Academy of Sciences Universities Violence Vision Vulnerable Populations Work biological systems care providers clinical practice community engagement community organizations design disorder risk experience food insecurity hazard health care delivery health equity health equity promotion improved innovation land use lens meetings metropolitan mortality multidisciplinary nutrition portrayal of violence in the media segregation social social determinants social interventions tool translational medicine underserved minority

项目摘要

Contact PD/PI: Solway, Julian Chapter O: Overall ABSTRACT ITM 3.0: ADVANCING HEALTH TOWARD HEALTH EQUITY THROUGHOUT METROPOLITAN CHICAGO The University of Chicago – Rush University Institute for Translational Medicine (ITM) was created in 2007 to assemble, integrate, and create the intellectual, administrative, and physical resources required to catalyze research and research training in Clinical and Translational Science. We have trained university scientists and health care providers as well as stakeholders from concerned communities to work together to determine the biological, behavioral, and social determinants of disease; to develop and test interventions directed toward those mechanisms; and to achieve these goals in a way that is rigorous, efficient, ethical, respectful of, and responsive to our communities’ priorities and values. The ITM has capitalized on outstanding intellectual and physical resources throughout UChicago, Rush, and ITM affiliate institutions – Loyola University Chicago, NorthShore University HealthSystem, Advocate Aurora Health Care, and Illinois Institute of Technology – and on substantial multi-institutional investments to build the sustainable infrastructure for a transformative, energetic, and self-improving home for clinical and translational research. Now, we pursue a bold guiding vision for “ITM 3.0” – that reversing the adverse health consequences of structural racism requires accounting for and mitigating the social, environmental, behavioral, and psychological factors (the entire lived experience, which we will call the “sociome”) through which structural racism impairs health. Focus on the sociome is critical because: 1) sociome factors interact with human biology to exacerbate or cause disease and injury, and 2) illness of any origin can compound the negative effects of adverse sociome factors. Since both sociome and biological systems, and their interactions, determine health, our CTSA hub must provide investigators, trainees, and stakeholders with the resources and knowledge to account for and address health disruptors throughout both systems. Our strategy to implement this vision is to create new training mechanisms, research platforms, communications channels, and safeguards against harm to ensure that all ITM investigators and institutions approach health problems with a wider-angle sociome lens in an ethical way. Then, our scientific, institutional, and community stakeholders can together design, test, and disseminate biological and/or sociome-directed interventions at the levels of individual, community, and society to improve mutually defined health concerns. ITM 3.0 will work hand-in-hand with partners throughout Chicagoland and the nation, combining academic rigor with community wisdom to conceptualize, develop and deploy innovative, just, and ethical interventions/practices to achieve our common goal, and so lessen the health impact of structural racism. Project Summary/Abstract Page 244 Contact PD/PI: Solway, Julian

联系人 PD/PI：Solway、Julian O 章：总体抽象的 ITM 3.0：在整个芝加哥大都会促进健康，实现健康公平芝加哥大学-拉什大学转化医学研究所 (ITM) 成立于 2007 年，汇集、整合和创造催化所需的智力、管理和物质资源我们培训了大学科学家和临床和转化科学方面的研究和研究培训。卫生保健提供者以及相关社区的利益相关者共同努力确定疾病的生物学、行为和社会决定因素；开发和测试针对该疾病的干预措施这些机制；并以严格、高效、道德、尊重和尊重的方式实现这些目标 ITM 积极响应我们社区的优先事项和价值观。整个芝加哥大学、Rush 和 ITM 附属机构（芝加哥洛约拉大学）的物理资源，北岸大学医疗系统、Advocate Aurora Health Care 和伊利诺伊理工学院 – 以及进行大量多机构投资，建设可持续基础设施，以实现变革、充满活力、自我完善的临床和转化研究之家。现在，我们追求“ITM 3.0”的大胆指导愿景——扭转对健康的不利影响结构性种族主义需要考虑和减轻社会、环境、行为和心理因素（整个生活经历，我们称之为“社会组”）结构性种族主义损害健康。关注社会群体至关重要，因为：1）社会群体因素相互作用。人类生物学恶化或导致疾病和伤害，2) 任何来源的疾病都可能加剧不利的社会组学因素的负面影响，因为社会组学和生物系统及其它们。相互作用、确定健康状况，我们的 CTSA 中心必须为调查人员、受训人员和利益相关者提供资源和知识来解释和解决两个系统中的健康干扰因素。实现这一愿景的战略是创建新的培训机制、研究平台、沟通渠道，并防范伤害，以确保所有 ITM 调查员和机构以更广泛的社会视角以道德的方式处理健康问题。科学、机构和社区利益相关者可以共同设计、测试和传播生物技术和/或在个人、社区和社会层面进行以社会为导向的干预措施，以改善 ITM 3.0 将与整个芝加哥地区的合作伙伴携手合作。国家、学术界将严谨与社区智慧相结合，进行概念化、开发和部署创新、公正和符合道德的干预措施/做法，以实现我们的共同目标，从而减少健康结构性种族主义的影响。项目总结/摘要第 244 页联系人 PD/PI：Solway、Julian