Imperial County Clinical Research Network for Health Equity

帝国县健康公平临床研究网络

基本信息

批准号：
10631785
负责人：
GUADALUPE X AYALA
金额：
$ 132.61万
依托单位：
SAN DIEGO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-24 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10631785
关键词：
Address Advisory Committees Award Awareness Border Community Breastfed infant California Clinical Research Cohort Studies Collaborations Common Data Element Communities Complex Computerized Medical Record County Data Data Analyses Data Collection Development Disease Effectiveness Ensure Evaluation Exclusive Breastfeeding Family Fostering Funding Goals Health Health Disparities Research Health Promotion Healthcare Healthcare Systems Household Human Resources Income Infrastructure Institutional Review Boards Interdisciplinary Study Knowledge Lactation Language Logic Medical center Mental Health Methods Mexico Modeling National Institute on Minority Health and Health Disparities Obesity Outcome Participant Patients Personal Satisfaction Phase Pilot Projects Plant Roots Poaceae Policies Population Postdoctoral Fellow Practice based research Prenatal care Procedures Process Protocols documentation Research Research Infrastructure Research Personnel Research Priority Research Support Resources Risk Rural Rural Community Scientific Inquiry Site System Testing Time TimeLine Treatment Efficacy U-Series Cooperative Agreements Underserved Population Weight career clinical practice clinical research site contextual factors data harmonization data sharing effectiveness trial follow-up health disparity health equity implementation efforts infrastructure development innovation member minority health disparity novel strategies overweight child pragmatic trial programs protocol development response secondary analysis shared decision making social determinants student participation suburb

项目摘要

PROJECT SUMMARY This 5-year effort titled “Leveraging a Regional Clinical Practice Research Network for Health Equity in the Rural, Border Region of Imperial County, California (Imperial County Clinical Research Network)” seeks to advance minority health and health disparities research by establishing the personnel and systems (policies and procedures) infrastructure to support clinical research within a regional medical center that serves a rural, border community in Southern California. It accomplishes this by bringing together three primary organizations and their respective leaders to develop a disease-agnostic research agenda consistent with the needs of patients, diverse clinicians and multi-sectoral community stakeholders. Infrastructure will be developed to support both observational (e.g., cohort studies; secondary analyses using electronic medical record [EMR] data) and intervention (from efficacy to effectiveness trials) research. During the UG3 phase, we propose to develop the research infrastructure to support the implementation of a pragmatic trial as this provides the strongest possible infrastructure for supporting PP2, which will be determined through a competitive process. The UG3 phase also will advance data sharing activities including identifying a set of common data elements across Network sites, and developing and testing protocols and systems for sharing data, including EMR data from multiple systems. During the UH3 phase (Y3-5), both PPs will be launched following final approval from the Multidisciplinary Research Council and the SDSU IRB committee. PP1 proposes to test a robust Lactation Support Program to promote engagement in prenatal care and exclusive breastfeeding to ultimately reduce the rates of childhood overweight and obesity in Imperial County. The UH3 phase will continue to advance data sharing and promote dissemination through the development of protocols and systems for data verification, data harmonization, and meaningful interpretation of data given contextual factors (e.g., language of administration). The proposed timeline plans for data sharing and harmonization to occur with the PPs as early as possible (here in Y3), and with sufficient time at the end to complete final follow-up data collection from participants, and data submitted to the Coordinating Center in Y5. All of these efforts will be guided by the involvement of a Patient Advisory Committee (5 members), a Clinician Advisory Committee (15 diverse clinician types), and a Community Stakeholder Committee (12 diverse sector members). The ultimate goal of this effort is to identify feasible, sustainable, and translatable approaches to promote health and well-being in rural, border communities.

项目概要这项为期 5 年的工作题为“利用区域临床实践研究网络促进农村、加利福尼亚州因皮里尔县边境地区（因皮里尔县临床研究网络）”寻求推进通过建立人员和制度（政策和制度）来研究少数民族健康和健康差异程序）基础设施，以支持服务于农村、边境地区的区域医疗中心内的临床研究它通过将三个主要组织及其成员聚集在一起来实现这一目标。各自的领导者制定与患者、多样化需求一致的疾病不可知论研究议程将开发基础设施以支持两者观察性（例如队列研究；使用电子病历 [EMR] 数据进行二次分析）和干预（从功效到有效性试验）研究在UG3阶段，我们建议开发支持实施务实试验的研究基础设施，因为这提供了尽可能强大的支持支持 PP2 的基础设施也将通过 UG3 阶段的竞争过程来确定。将推进数据共享活动，包括识别网络站点上的一组通用数据元素，开发和测试用于共享数据的协议和系统，包括来自多个系统的 EMR 数据。在 UH3 阶段 (Y3-5)，两个 PP 将在获得多学科部门的最终批准后启动研究委员会和 SDSU IRB 委员会提议测试一项强有力的哺乳支持计划。促进产前护理和纯母乳喂养，以最终降低儿童出生率 UH3 阶段将继续推进数据共享并促进帝国县的超重和肥胖。通过开发数据验证、数据协调和数据协议和系统来传播在给定上下文因素（例如管理语言）的情况下对数据进行有意义的解释。尽早与 PP 进行数据共享和协调的时间表计划（此处为 Y3），以及最后有足够的时间完成参与者的最终后续数据收集，并将数据提交给 Y5 的协调中心将在患者咨询的参与下指导所有这些工作。委员会（5 名成员）、临床医生咨询委员会（15 种不同类型的临床医生）和社区利益相关者委员会（12 名不同部门的成员）这项工作的最终目标是确定可行的、促进农村、边境社区健康和福祉的可持续且可转化的方法。