Pilot and Feasibility

试点与可行性

• 批准号: 9057516
• 负责人: JOHN F ENGELHARDT
• 金额: $ 21.39万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9057516
• 关键词: Accountability; Achievement; Administrator; Advisory Committees; Area; Budgets; Clinical Sciences; Communities; Cystic Fibrosis; Databases; Decision Making; Documentation; Ensure; Evaluation; Funding; Goals; Grant; Group Meetings; Institutes; Iowa; Journals; Judgment; Leadership; Lung; Maintenance; Manuscripts; Medicine; Mentors; Molecular; Monitor; Postdoctoral Fellow; Questionnaires; Records; Recruitment Activity; Research; Research Personnel; Secure; Series; Services; Summary Reports; Supervision; System; Translational Research; Universities; Visit; abstracting; base; career; college; cost effective; gene therapy; graduate student; member; programs; research and development; web interface; web site; working group

Abstract/Summary (Administrative Core; Core 1) The Administrative Core provides oversight of the Center for Gene Therapy of Cystic Fibrosis, under the supervision of the Center Executive Committee and External Advisors. One major area of responsibility is largely administrative, including financial documentation and accountability for the Center's Pilot and Feasibility Program and its Cores, and oversight and documentation of external review of the Center overall. Three major governing bodies contribute to the review of various Center functions. The Pilot and Feasibility Committee oversees decisions regarding pilot funding, in conjunction with a Cystic Fibrosis Research and Development Program pilot program and an Institute for Clinical and Translational Science pilot program, with each pilot receiving two external reviews before a decision is made. The Executive Committee is the major decision- making body of the Center, and makes final judgments about the funding of new pilots and the renewal of ongoing pilots for a second year of funding. The External Advisory Committee provides direction to the Executive Committee, as does the College of Medicine leadership. A second major responsibility of this Core is to enrich CF-related scientific programs, and it does so through sustained membership and pilot recruitment efforts, scientific enrichment programs (seminar series, Center retreats, and less formal scientific working- group meetings), and assessment of the Center's Research Cores and their services (e.g., through investigator questionnaires and external review). Lastly, the Administrative Core acts as a conduit for research and services to both investigators outside the University of Iowa and the lay community (e.g., by maintaining the Center web site). In summary, the Administrative Core assists its members in making breakthroughs in CF research and molecular therapies by: 1) recruiting talented junior investigators into careers in CF research and mentoring them, through its pilot program and center activities; 2) assisting the Research Cores in providing efficient, high quality, and cost-effective services; and 3) providing forums for the exchange of new information and ideas among its members through its Enrichment Programs.

摘要/摘要（行政核心；核心1） 行政核心提供了对囊性纤维化基因治疗中心的监督 中心执行委员会和外部顾问的监督。一个主要的责任领域是 主要行政，包括对中心的飞行员的财务文件和问责制和可行性 计划及其核心以及整体中心外部审查的监督和记录。三个主要 理事机构有助于审查各种中心功能。飞行员和可行性委员会 与囊性纤维化研究和开发一起监督有关试点资金的决定 计划试点计划和临床和转化科学试验研究所，每个飞行员 在做出决定之前，请接受两个外部评论。执行委员会是主要决定 - 制作中心的尸体，并对新飞行员的资金和续签做出最终判断 正在进行的飞行员进行第二年的资金。外部咨询委员会向 执行委员会，医学院领导学院也是如此。该核心的第二个主要责任是 丰富与CF相关的科学计划，并通过持续的会员和试点招聘来实现 努力，科学丰富计划（研讨会系列，中心务虚会以及较不正式的科学工作 - 小组会议），并评估中心的研究核心及其服务（例如，通过调查员 问卷和外部审查）。最后，行政核心充当研究的渠道和 为爱荷华大学和外行社区以外的两个调查人员提供服务（例如，维护 中心网站）。总而言之，行政核心协助其成员在CF中取得突破 研究和分子疗法作者：1）招募有才华的初级研究人员从事CF研究和 通过其试点计划和中心活动来指导它们； 2）协助研究核心提供 高效，高质量和具有成本效益的服务； 3）提供论坛以交换新信息 以及其成员通过其丰富计划之间的想法。