Center Administration

中心行政

• 批准号: 10270097
• 负责人: Peter CM Van Zijl
• 金额: $ 66.57万
• 依托单位: HUGO W. MOSER RES INST KENNEDY KRIEGER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270097
• 关键词: Advisory Committees; Anatomy; Area; Baltimore; Beds; Biological Markers; Biomedical Engineering; Biometry; Brain imaging; Clinic; Collaborations; Computer software; Development; Engineering; Environment; Equipment; Faculty; Goals; Grant; Head; Health; Human; Image; Imaging technology; Institutes; Institution; Interdisciplinary Study; International; Internet; Letters; Magnetic Resonance; Magnetic Resonance Imaging; Maintenance; Medical; Metabolic; Methodology; National Institute of Biomedical Imaging and Bioengineering; Physiological; Procedures; Progress Reports; Protocols documentation; Public Health Schools; Radiology Specialty; Reporting; Research; Research Project Grants; Resources; Review Committee; Safety; Scheme; Schools; Science; Scientist; Services; Site; System; Technology; Testing; Training; Translating; United States National Institutes of Health; Universities; Validation; base; biomarker development; collaborative environment; contrast imaging; data exchange; design; experience; interest; investigator training; magnetic resonance imaging biomarker; medical schools; member; multimodality; new technology; operation; organizational structure; professor; research and development; spectroscopic imaging; success; technology development

SUMMARY The MRI Resource for Physiologic, Metabolic and Anatomic Biomarkers has an Administrative Core that coordinates all NCBIB activities, i.e. the development and dissemination of qualitative and quantitative MRI biomarker technologies based on fast multi-modal multi-contrast imaging and spectroscopy approaches, as well as the training in their use. Daily operation of all aspects of the NCBIB is the responsibility of the MPIs of this core, Drs. Peter van Zijl and Hanzhang Lu, both experts in magnetic resonance technology development with longstanding experience in managing NIH grants and multicenter and multi-disciplinary collaborations. They head the Resource Executive Committee in which they will manage this task through close interaction with the other PIs heading the four technical research and development (TRD) projects. The full committee meets bimonthly or whenever necessary. The TRD PIs are all in close proximity and meet/interact closely at least on a weekly basis. The general goals of the Resource are formulated by this Executive Committee with guidance from the internal and external advisory committees. The main goal is to create an environment that allows biomarker technology development through the push-pull interaction between the physicists and engineers of the TRDs and the application scientists and clinicians heading the collaborative projects. In addition, the Resource supports many service projects as test beds of the methodology in important areas of application. The committee also assures that technology is further disseminated through presentations, training courses, and software and data transfer to interested sites (See Training and Dissemination Section). The Resource has a set of carefully designed operating procedures to establish the above-mentioned collaborative and service projects and for the management of the facilities in terms of safety and equitable access to the scanners and facilities. Plans for long-term maintenance of the facility assure that the NCBIB can function successfully. The progress of the Resource will be overseen by an External Advisory Committee (EAC) consisting of experts in biomarker development and in the technical fields of our TRDs. This committee will meet annually to advise on scientific progress and on the progress of the center in terms of its goals of collaboration, service, training and dissemination. A yearly report will be submitted to NIBIB as part of the annual progress report. In addition to the EAC, we have several local committees that provide oversight, including a protocol review committee that evaluates all research projects in terms of human safety and research quality. The Resource has very strong institutional support, as outlined in letters by the president of Kennedy Krieger Institute and the Chairs of Radiology and Biomedical Engineering at Johns Hopkins University.

概括 生理、代谢和解剖生物标志物的 MRI 资源有一个管理核心， 协调所有 NCBIB 活动，即定性和定量 MRI 的开发和传播 基于快速多模态多对比成像和光谱方法的生物标记技术，如 以及使用它们的培训。 NCBIB 各个方面的日常运作由该核心的 MPI 负责，Drs.彼得·范·齐尔和 陆汉章，两位磁共振技术开发专家，拥有长期的磁共振技术开发经验 管理 NIH 拨款以及多中心和多学科合作。他们领导资源执行官 他们将在委员会中通过与领导这四个项目的其他 PI 密切互动来管理这项任务 技术研究与开发（TRD）项目。全体委员会每两个月举行一次会议，或随时举行会议 必要的。 TRD PI 都非常接近，并且至少每周都会密切会面/互动。这 该资源的总体目标由执行委员会在内部和外部的指导下制定 外部咨询委员会。主要目标是创造一个允许生物标记技术的环境 通过 TRD 的物理学家和工程师之间的推拉互动进行开发 应用科学家和临床医生领导合作项目。此外，该资源支持 许多服务项目作为该方法在重要应用领域的测试平台。委员会还 确保通过演示、培训课程以及软件和数据进一步传播技术 转移到感兴趣的站点（参见培训和传播部分）。 该资源有一套精心设计的操作程序来建立上述 协作和服务项目以及设施的安全和公平管理 使用扫描仪和设施。设施的长期维护计划确保 NCBIB 能够 功能成功。 该资源的进展将由专家组成的外部咨询委员会（EAC）监督 在生物标志物开发和我们的 TRD 技术领域。该委员会将每年举行一次会议，以提供建议 关于科学进步以及中心在合作、服务、培训目标方面取得的进展 和传播。年度报告将作为年度进度报告的一部分提交给 NIBIB。此外 对于 EAC，我们有几个地方委员会提供监督，包括协议审查委员会 从人类安全和研究质量方面评估所有研究项目。 正如肯尼迪·克里格总统在信中所述，该资源拥有非常强大的机构支持 约翰霍普金斯大学放射学和生物医学工程研究所和主席。