Physician-Scientist Training in Emerging Infectious Diseases

新发传染病的医师科学家培训

• 批准号: 10270872
• 负责人: Peter C. Melby
• 金额: $ 8.95万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-22 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270872
• 关键词: Emerging Communicable Diseases; Physicians; Scientist; Training

PROJECT SUMMARY/ABSTRACT This new Institutional Training Grant (T32) application from the University of Texas Medical Branch (UTMB) will provide multidisciplinary and interprofessional research training for physician-scientists in emerging infectious diseases (EIDs). The ongoing risk and likelihood of facing outbreaks and epidemics caused by EIDs highlights a critical need for developing physician-scientists with trans-disciplinary skills in clinical medicine, epidemiology, field investigation, laboratory science, and biocontainment. The program capitalizes on world- class faculty expertise, longstanding institutional commitments, and unique research resources. It includes targeted recruitment of candidates at local, regional and national levels. Candidates will be physicians who are completing or have completed, an ACGME-certified residency or fellowship. One trainee per year will enter and complete 2-3 years of training during the 5-year program. Training includes instruction and mentorship in 1) team science; 2) research design, epidemiological methods, and biostatistics (MSc in Clinical Science); 3) EIDs and outbreak investigation; 4) clinical and research biocontainment/biosafety; 5) responsible conduct of research; 6) field epidemiology; and 7) scientific writing. Each of the trainees will apply their training by conducting translational research while receiving intensive scientific and career mentorship through a novel Team Science framework called individualized Multidisciplinary, Interprofessional Mentorship Team (iMIMT). Each iMIMT will include the trainee, a primary and secondary mentor (a PhD scientist and a MD scientist), and 2 or 3 peer or specialized knowledge mentors. iMIMTs will receive regular Team Science training and coaching. Instruction in grant writing will culminate in submission of an NIH career development application in the last year of training. Regular, but limited clinical responsibility will enable trainees to maintain clinical skills and learn how to manage a dual clinical-research career. Our 29 program faculty have productive translational research programs in EIDs and a record of successful mentoring. They are complemented by collaborating investigators from Peru, Colombia, Mexico, Dominican Republic, and Brazil. Additional program support faculty have specialized expertise for programmatic/operational support. The trainees' individualized development plan includes well-defined training activities, expected competencies, indicators of success, and a timeline for completion. Co-Program Directors and 3 Associate Program Directors will lead the program under Steering Committee governance. Sub-committees will oversee trainees' recruitment and selection, mentorship, and scientific progress. An External Advisory Committee will evaluate the program's progress annually. At completion, our trainees will have strong trans-disciplinary understanding of EIDs, will be grounded in research methods and outbreak investigation, will have tools for collaborative problem-solving, and critical skills in manuscript and grant writing. All of these will facilitate their transition to an independent physician-scientist.

项目概要/摘要 德克萨斯大学医学分部 (UTMB) 的这项新机构培训补助金 (T32) 申请将 为新兴传染病领域的医师科学家提供多学科和跨专业的研究培训 疾病（EID）。面临新发传染病爆发和流行病的持续风险和可能性凸显 迫切需要培养具有临床医学跨学科技能的医师科学家， 流行病学、现场调查、实验室科学和生物防护。该计划利用了世界 一流的师资专业知识、长期的机构承诺和独特的研究资源。它包括 在地方、区域和国家各级有针对性地招聘候选人。候选人将是医生 完成或已经完成 ACGME 认证的住院医师或研究金。每年一名实习生将进入并 在5年计划中完成2-3年的培训。培训包括以下方面的指导和指导：1) 团队科学； 2）研究设计、流行病学方法和生物统计学（临床科学硕士）； 3） EID 和疫情调查； 4）临床和研究生物防护/生物安全； 5) 负责任的行为 研究; 6）现场流行病学； 7）科学写作。每位学员将通过以下方式应用他们的培训 进行转化研究，同时通过小说接受密集的科学和职业指导 团队科学框架称为个性化多学科、跨专业指导团队 (iMIMT)。 每个 iMIMT 将包括受训者、一名初级和二级导师（一名博士科学家和一名医学博士科学家），以及 2 或 3 名同行或专业知识导师。 iMIMT 将定期接受团队科学培训并 辅导。拨款写作指导将最终提交 NIH 职业发展申请 培训的最后一年。定期但有限的临床责任将使学员能够保持临床技能 并学习如何管理双重临床研究职业。我们的 29 名项目教师拥有高效的翻译能力 EID 方面的研究项目和成功指导的记录。它们通过合作得到补充 调查人员来自秘鲁、哥伦比亚、墨西哥、多米尼加共和国和巴西。额外的项目支持教师 拥有程序/运营支持的专业知识。学员的个性化发展 计划包括明确的培训活动、预期能力、成功指标以及时间表 完成。联合项目总监和 3 名副项目总监将在指导下领导该项目 委员会治理。小组委员会将监督学员的招募和选拔、指导和培训 科学进步。外部咨询委员会将每年评估该计划的进展。在 完成后，我们的学员将对 EID 拥有深入的跨学科理解，并将以研究为基础 方法和疫情调查，将拥有协作解决问题的工具和关键技能 手稿和赠款写作。所有这些都将促进他们向独立医师科学家的转变。