Rapid Actionable Data for Opioid Response in Kentucky (RADOR-KY)

肯塔基州阿片类药物反应的快速可操作数据 (RADOR-KY)

• 批准号: 10588669
• 负责人: Svetla Stefanova Slavova
• 金额: $ 312.58万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2025-09-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10588669
• 关键词: Agreement; Algorithms; Area; COVID-19 pandemic; Centers for Disease Control and Prevention (U.S.); Code; Communities; County; Data; Data Linkages; Data Reporting; Development; Environment; Epidemic; Evidence based practice; Evidence based treatment; Goals; Harm Reduction; Health; Heterogeneity; Informatics; Information Systems; Infrastructure; Intervention; Kentucky; Link; Machine Learning; Measures; Methodology; Monitor; Morbidity - disease rate; National Institute of Drug Abuse; Online Systems; Opioid; Outcome; Overdose; Persons; Pharmaceutical Preparations; Policy Maker; Population Surveillance; Predictive Analytics; Prevention; Prevention Research; Public Health; Randomized Clinical Trials; Recovery; Reporting; Research; Research Institute; Resource Allocation; Risk; State Government; Statistical Models; Stimulant; System; Thinness; Time; Universities; Visual; Visualization; Visualization software; Waiting Lists; Work; addiction; alcohol research; base; biomedical informatics; computerized data processing; dashboard; data ecosystem; data ingestion; data quality; experience; healing; improved; informatics infrastructure; injury prevention; longitudinal dataset; mortality; multiple datasets; next generation; opioid epidemic; opioid exposure; opioid mortality; opioid overdose; opioid use disorder; overdose death; overdose prevention; population based; population health; prevent; public repository; response; trend

Abstract Opioid use disorder (OUD) remains a persistent public health crisis and epidemic. In spite of robust national, state, and local public health responses to the epidemic, opioid overdose deaths continue to increase; of the 91,799 drug overdose deaths in 2020, reported by the Centers for Disease Control and Prevention (CDC), the majority, 68,630 (75%) involved opioids, a 38% increase from 2019. The opioid overdose death burden in Kentucky is even higher, with a 63% increase from 2019 (n=1,036) to 2020 (n=1,688). In the context of the dynamically changing opioid epidemic, complicated by the challenges presented by the COVID-19 pandemic, agencies and organizations responsible for monitoring and improving the health of the population need timely state and local data to make critical decisions on resource allocation and targeted responses. Such decisions are typically related to a set of evidence-based practices (EBPs) aimed at preventing opioid overdose mortality. We will harness the infrastructure and methodological expertise at the University of Kentucky (UK) research centers (incl. the Kentucky Injury Prevention and Research Center, the Center on Drug and Alcohol Research, and the Institute for Biomedical Informatics), along with the experience gained from our work on the HEALing Communities Study supported by the National Institute on Drug Abuse, and the Overdose Data to Action project sponsored by the CDC. The specific aims of this project are to establish the Rapid Actionable Data for Opioid Response in Kentucky (RADOR-KY)– an integrated, population-based, near-real time statewide surveillance system that will ingest data from multiple state agencies and implement advanced informatics algorithms for fast data processing, data linkage, machine learning and predictive analytics to shorten the time between data capture and when analytical results are available to support opioid overdose prevention and control. RADOR-KY will have mobile and web-based applications to provide immediate dissemination and access to near-real time community or state level data, reports, and visual analytics to share with agencies and community end-users. RADOR-KY End-user Advisory Group, including partners in state government and local communities, will guide the development of the RADOR-KY reporting and visualization functionality. RADOR- KY will establish a longitudinal dataset accessible thru the RADOR-KY portal and also shared within the HEAL Data Ecosystem. Programming code for implemented algorithms and web-based dashboards will be shared in a public repository to advance the efforts to mitigate the opioid epidemic across the U.S.

抽象的 尽管全国范围内阿片类药物使用障碍（OUD）仍然是一个持续存在的公共卫生危机和流行病。 各州和地方公共卫生部门针对这一流行病的反应，阿片类药物过量死亡人数持续增加； 美国疾病控制与预防中心 (CDC) 报告称，2020 年有 91,799 人因药物过量死亡 其中 68,630 例 (75%) 涉及阿片类药物，比 2019 年增加了 38%。阿片类药物过量死亡负担 肯塔基州甚至更高，从 2019 年（n=1,036）到 2020 年（n=1,688）增加了 63%。 动态变化的阿片类药物流行病，因 COVID-19 大流行带来的挑战而变得更加复杂， 负责监测和改善人口健康的机构和组织需要及时 州和地方数据，以做出有关资源分配和有针对性的响应的关键决策。 通常与一系列旨在预防阿片类药物过量死亡的循证实践 (EBP) 有关。 我们将利用肯塔基大学（英国）研究的基础设施和方法专业知识 中心（包括肯塔基州伤害预防和研究中心、药物和酒精研究中心、 和生物医学信息学研究所），以及我们在 HEALing 工作中获得的经验 由国家药物滥用研究所支持的社区研究以及采取行动的过量数据 该项目由 CDC 赞助，其具体目标是建立快速可操作数据。 肯塔基州的阿片类药物反应 (RADOR-KY) – 一个综合的、基于人口的、近实时的检察官 监控系统将从多个国家机构获取数据并实施先进的信息学 用于快速数据处理、数据链接、机器学习和预测分析的算法，以缩短时间 在数据采集和分析结果可用于支持阿片类药物过量预防之间 RADOR-KY 将拥有移动和基于网络的应用程序来提供即时传播和控制。 访问近乎实时的社区或州级数据、报告和可视化分析，以便与机构和机构共享 RADOR-KY 最终用户咨询小组，包括州政府和当地的合作伙伴。 社区，将指导 RADOR-KY 报告和可视化功能的开发。 KY 将建立一个可通过 RADOR-KY 门户访问并在 HEAL 内共享的纵向数据集 数据生态系统。实现算法和基于网络的仪表板的编程代码将在 一个公共存储库，旨在推动减轻美国各地阿片类药物流行的努力