Administrative Core

行政核心

基本信息

批准号：
10613999
负责人：
Mary Sano
金额：
$ 65.56万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-05-01 至 2025-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10613999
关键词：
Accountability Action Research Address Administrator Advisory Committees Alzheimer disease prevention Alzheimer&apos s Disease Animals Applied Research Articulation Budgets Calendar Clinical Collaborations Communication Communities Data Data Collection Dementia Detection Development Diagnosis Diagnostic Disease Education Ensure Evaluation Event Faculty Faculty Recruitment Fostering Funding Funding Agency Goals Health Insurance Portability and Accountability Act Health system Heterogeneity Infrastructure Institution International Knowledge Leadership Location Mentors Mission Monitor Performance Process Productivity Regulation Research Research Personnel Resource Allocation Resources Sampling Science Structure Technology Therapeutic Translational Research cell repository cohort comorbidity disease heterogeneity education research human subject improved knowledge of results medical schools meetings outreach programs recruit resilience factor resource guides sample collection success

项目摘要

Mount Sinai ADRC (Sano): Administrative Core (Core A) – Research Summary The Administrative Core of the MSADRC provides leadership to manage and coordinate the research agenda for the MSADRC to ensure success in our mission to “Understand disease heterogeneity to optimize therapeutic approaches to treat and cure Alzheimer's disease”. The overall aims are as follows. 1) To provide leadership and an operational infrastructure to facilitate communication among cores, and with national entities including NIA program staff, National Alzheimer's Disease Coordinating Center (NACC) and the National Cell Repository for Alzheimer's Disease (NCRAD). The structure includes an Executive Committee (EC) an External Advisory Committee (EAC), and an Internal Advisory Committee. The Core also maintains administrative, financial and regulatory oversight. 2) To ensure that the MSADRC addresses the agenda of the National Alzheimer's Project Act (NAPA). 3) To create a program that supports developmental projects that will stimulate Alzheimer's disease (AD) research around the institution. 4) To evaluate all activities to ensure they generate the planned resources and disseminate them broadly, and to optimize their impact on finding a cure for AD. The Administrative Core oversees activities across two locations, the Icahn School of Medicine at Mount Sinai (ISMMS) and the James J Peters VAMC. Through a clear structure for governance, with a set of advisory and working committees, and a calendar of meetings with prescribed agendas, the Administrative Core assures coordinated interaction among the Directors and the Core Leaders. The Administrative Core assures that the recruitment and retention of a diverse cohort, the data and sample collection, and data distribution all occur in a timely manner. It assists the Research Education Component in its task to identify AD Scholars successfully, enrich their education through mentoring from all of the MSADRC Core Leaders and enhance their research opportunities using resources provided by the Cores. This is achieved through regular meetings with all Core staff to address operational issues and to foster collaboration across MSADRC faculty, and with other AD researchers within ISMMS and beyond. The Administrative Core guarantees that data and samples are provided to NACC and NCRAD in a timely manner; it is responsible for communicating with the funding agency, the NIA Center program leaders and staff, to promote dissemination of research findings and opportunities to the widest community. The Core administrator oversees fiscal and regulatory issues, guaranteeing compliance with guidance for human subject and animal protection, organizes the annual call for Developmental Projects including preparing and disseminating a call for proposals and organizing a scientific review under the leadership of the MSADRC Director and Associate Directors. The administrator also assists with tracking evaluations of core performance, REC success, productivity of Developmental Projects, and faculty recruitment and promotion. !

西奈山 ADRC（萨诺）：行政核心（核心 A）——研究摘要 MSADRC 的行政核心负责管理和协调研究议程为 MSADRC 确保我们的使命“了解疾病异质性以优化治疗和治愈阿尔茨海默病的治疗方法”的总体目标如下： 1) 提供。领导层和业务基础设施，以促进核心之间以及与国家实体的沟通包括 NIA 项目工作人员、国家阿尔茨海默病协调中心 (NACC) 和国家细胞阿尔茨海默病知识库 (NCRAD) 该结构包括执行委员会 (EC) 和核心还设有外部咨询委员会 (EAC) 和内部咨询委员会。行政、财务和监管监督 2) 确保 MSADRC 处理 MSADRC 的议程。国家阿尔茨海默氏症项目法案 (NAPA) 3) 创建一个支持发展项目的计划：将刺激机构内的阿尔茨海默病 (AD) 研究 4) 评估所有活动以确保。他们生成计划资源并广泛传播，并优化其对寻找目标的影响行政核心负责监督两个地点的活动：伊坎医学院 (Icahn School of Medicine)。西奈山 (ISMMS) 和 James J Peters VAMC 通过一套清晰的治理结构。咨询委员会和工作委员会以及规定议程的会议日历、行政核心确保董事和核心领导者之间的协调互动。确保招募和保留多样化群体、数据和样本收集以及数据它协助研究教育部门完成识别 AD 的任务。通过所有 MSADRC 核心领导人的指导，学者们成功地丰富了他们的教育利用核心提供的资源增加他们的研究机会这是通过定期实现的。与所有核心员工举行会议，以解决运营问题并促进 MSADRC 教员之间的合作，以及 ISMMS 及其他领域的其他 AD 研究人员，行政核心保证数据和安全。及时向NACC和NCRAD提供样品，负责与NACC和NCRAD进行沟通；资助机构、NIA 中心项目领导和工作人员，以促进研究成果的传播和核心管理员负责监督财政和监管问题，确保遵守人类受试者和动物保护指南，组织年度呼吁发展项目包括准备和传播提案征集以及组织科学活动评审工作在市防改中心主任、副主任领导下进行，管理员协助。跟踪评估核心绩效、REC 成功、发展项目的生产力，以及教师招聘和晋升。！