Yale Center for Sleep Disturbance in Acute and Chronic Conditions

耶鲁大学急性和慢性疾病睡眠障碍中心

• 批准号: 9079278
• 负责人: Nancy S Redeker
• 金额: $ 28.49万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-27 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9079278
• 关键词: Acute; Address; Adult; American; Behavior Therapy; Behavioral; Cardiovascular Diseases; Cause of Death; Cessation of life; Chronic; Chronic Disease; Clinical; Consultations; Data Analytics; Development; Diabetes Mellitus; Discipline of Nursing; Doctor of Philosophy; Emotional; Epidemiology; Fatigue; Functional disorder; Goals; Health; Home Care Services; Human; Intervention; Knowledge; Lead; Leadership; Life; Life Style; Longevity; Measurement; Medical; Medicine; Mental Depression; Mental disorders; Mentorship; Methods; Mission; Morbidity - disease rate; Nature; Obesity; Outcome; Pain; Patient Outcomes Assessments; Phase; Pilot Projects; Polysomnography; Population; Quality of life; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Risk Factors; Robin bird; School Nursing; Scientist; Self Management; Sleep; Sleep disturbances; Staging; Statistical Methods; Stroke; Substance abuse problem; Survivors; Symptoms; Testing; base; biobehavior; common symptom; disability; experience; family management; improved; lifestyle intervention; method development; mortality; research study; response; therapy development; treatment effect

DESCRIPTION (provided by applicant): The proposed Yale Center for Sleep Disturbance in Acute and Chronic Conditions will focus on the creation of knowledge that will lead to improvements in the assessment and bio-behavioral management of sleep disturbance across the trajectory of acute and chronic conditions and ultimate improvements in patient-reported outcomes, morbidity, and mortality. The Center will build on the strong research relationships among the Yale Schools of Nursing and Medicine and the Yale CTSA and our interdisciplinary expertise in sleep disturbance, management of acute and chronic conditions, and methods of development and testing of self- and family management interventions. The aims of this project and the goals of the Center are to: 1) Expand the number and quality of research studies designed to improve understanding of the bio-behavioral relationships between sleep disturbance and acute and chronic conditions; the contributions of sleep disturbance to morbidity, mortality, function and quality of life; and assessment and biobehavioral management of sleep disturbance in acute/chronic conditions among populations spanning the human lifespan and in various home and health care settings; 2) Develop expertise among Center investigators in: ecologically valid sleep measurement methods that best capture the sleep attributes and sleep-related outcomes that are important in acute/chronic conditions and feasible in various populations and settings; statistical methods that address the multi-dimensional and temporal nature of sleep disturbance; and development and testing of interventions for management and self-management of sleep disturbance in acute/chronic conditions; 3) Build and sustain interdisciplinary partnerships within Yale and with external partners, including those in other NINR Centers, to increase research on sleep disturbance in acute/chronic conditions; and 4) Expand the strong research infrastructure at Yale to provide enhanced support for interdisciplinary sleep disturbance research. A Methods Core will support the scientific directions of the Center and four pilot studies will be conducted by promising junio scientists.

描述（由申请人提供）：拟议的耶鲁大学睡眠障碍中心在急性和慢性状况下将集中于创建知识，这将改善急性和慢性病轨迹的睡眠障碍的评估和生物行为管理，以及患者报道的表现，良好的结果，道德和死亡率，良好的轨迹和最终改善。该中心将基于耶鲁大学护理和医学学校与耶鲁大学CTSA的牢固研究关系，以及我们在睡眠障碍，急性和慢性病管理以及自我和家庭管理干预措施的发展和测试方法方面的跨学科专业知识。该项目的目的和中心的目标是：1）扩大研究研究的数量和质量，旨在提高对睡眠障碍与急性和急性和慢性病之间的生物行为关系的了解；睡眠障碍对发病率，死亡率，功能和生活质量的贡献；在人类寿命以及各种家庭和卫生保健环境中，在急性/慢性状况下对睡眠障碍的评估和生物行为管理； 2）在中心研究人员之间发展专业知识：在生态有效的睡眠测量方法中，最能捕获睡眠属性和与睡眠有关的结果，这些结局在急性/慢性病中很重要，并且在各种种群和环境中可行；统计方法涉及睡眠障碍的多维和时间性质的统计方法；以及在急性/慢性条件下进行管理和自我管理干预措施的干预措施的开发和测试； 3）在耶鲁大学和包括其他忍者中心的外部合作伙伴内建立和维持跨学科的伙伴关系，以增加急性/慢性病的睡眠障碍研究； 4）扩大耶鲁大学的强大研究基础设施，以增强对跨学科睡眠障碍研究的支持。方法核心将支持该中心的科学方向，并将通过有希望的Junio科学家进行四个试点研究。