Harmonized Diagnostic Assessment of Dementia (DAD) for Longitudinal Aging Study in India (LASI)

印度纵向老龄化研究 (LASI) 痴呆症统一诊断评估 (DAD)

• 批准号: 9307615
• 负责人: Jinkook Lee
• 金额: $ 8.6万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-15 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9307615
• 关键词: Age-Years; Aging; Award; Blood; Blood specimen; Caring; Castes; Characteristics; China; Clinical assessments; Cognition; Communities; Computer Assisted; Country; Data; Data Analyses; Dementia; Deterioration; Developing Countries; Diagnostic; Economics; Educational Background; Elderly; England; Enrollment; Episodic memory; Evaluation; Feasibility Studies; Foundations; Funding; Gender; Goals; Government; Grant; Health; Hospital Administration; Hospitals; Impaired cognition; India; Individual; Institution; Interview; Investigation; Knowledge; Link; MRI Scans; Mental Health; Monitor; Nature; Older Population; Outcome; Participant; Performance; Personal Satisfaction; Persons; Physical Performance; Pilot Projects; Policies; Population; Prevalence; Probability; Protocols documentation; Psyche structure; Research; Research Personnel; Respondent; Retirement; Sampling; Scientific Advances and Accomplishments; Scientist; Sister; Social Policies; Specimen; Spottings; Staging; Surveys; Test Result; Time; United States; Variant; Venous; Woman; Work; age group; aged; base; behavioral outcome; care giving burden; care systems; cognitive ability; cognitive function; cognitive performance; cognitive testing; community setting; cost; evidence base; experience; health disparity; informant; innovation; insight; mathematical ability; mild cognitive impairment; multidisciplinary; performance tests; prognostic; social; social situation

 DESCRIPTION (provided by applicant): India, the second-most populous country in the world, will soon experience rapid aging of its population. By 2050, India's older population (> 60 years old) is projected to reach 320 million (about the current size of the entire US population), representing an increase from 8 to 20 percent of its total population. The growing number of older people will drive a large increase in the prevalence of dementia in India, far exceeding the capacity of the private care system that currently predominates for the elderly. The Longitudinal Aging Study in India (LASI), a survey of 50,000 Indians representative of the older population across the nation and within its states and union territories, provides a unique opportunity to examine this and related issues. LASI is the most ambitious nationally representative study of the physical, mental, economic, and social well-being of the country's older population. Harmonized with other Health and Retirement Study (HRS) surveys, it offers an evidence base that can be used to compare the effects of social policies aimed at supporting older persons in India with policies used in other countries around the world. The objective of the proposed research is to supplement the current LASI in order to estimate the prevalence of dementia and mild cognitive impairment (MCI) in India. Previous efforts to identify dementia in developing nations have typically relied on non- representative samples in geographically restricted regions. In this application, we aim to develop a protocol for the assessment of dementia and MCI to be used within community settings in the ongoing, nationally representative LASI. To do so, we will first conduct in-depth cognitive testing for a sub-sample of LASI respondents at regional geriatric hospitals in India. Specifically, we will administer two leading dementia assessment protocols - the HRS Harmonized Cognitive Assessment Protocol (HCAP) and the 10/66 Dementia Protocol - to approximately 2,000 respondents at least 60 years of age and stratified by their Wave 1 cognition test results, as well as their proximity to collaborating regional geriatic hospitals where the assessments will occur. Based on prognostic evaluation of the protocols, we will develop a short (15-minute) dementia assessment module and administer it in Wave 2 to persons with a high probability of having dementia and MCI as well as to the 2,000 persons participating in the earlier assessment. Using these data, we will estimate prevalence rates of dementia and MCI in India for the population and sub-populations. We will provide to the research community data generated from the in-depth cognitive testing at regional geriatric hospitals and from the administration of the short dementia assessment module during Wave 2, both linked to the on-going LASI main survey. Our harmonized protocol for dementia and MCI assessment will enable researchers to make comparisons with prior findings in India using the 10/66 protocol as well as to conduct cross-country studies with the United States, England, China, and other countries that implement the HRS HCAP protocol.

 描述（通过应用程序证明）：印度，全球旧人口中的第二大国家（> 60岁）预计将达到3.2亿（大约是整个美国人口的十字年度），E的患病率增加印度的痴呆症是在国家及其州和工会领土内占主导地位的私人护理体系的能力。在该国老年人口的身体，经济和社会福祉中，它与其他健康和退休研究（HRS）调查相比，它提供了一个证据基础，可用于比较旨在支持Oldia的社会政策的影响全球其他国家使用的政策是为了支持办公室中的痴呆症患病率和轻度认知障碍（MCI）。在此应用程序中，我们的目标是在持续的LASI中制定痴呆症的痴呆症协议。 。将基于对协议的程序统计评估进行评估的Geriatic医院，我们将开发一个简短（15分钟）有2,000名参与早期评估的人将对印度的痴呆症和MCI的患者进行，并从区域老年医院进行深入的认知测试和小型人群。 ，正在进行的LASI主要调查。 HRS HCAP协议。