Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods Study

酒精依赖者的睡眠障碍和复发：一项探索性混合方法研究

• 批准号: 9358267
• 负责人: Gwenyth R Wallen
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9358267
• 关键词: Abstinence; Accelerometer; Alcohol consumption; Alcohol dependence; Alcoholism; Back; Behavior; Behavioral; Belief; Cessation of life; Clinical Research; Communities; Complex; Data; Enrollment; Expectancy; Home environment; Individual; Inpatients; Interview; Investigation; Literature; Maintenance; Measures; Methods; Modeling; National Institute on Alcohol Abuse and Alcoholism; Outcome; Outpatients; Participant; Patients; Perception; Physical Dependence; Problem behavior; Process; Public Health; Publishing; Qualitative Methods; Recovery; Rehabilitation therapy; Relapse; Research; Sample Size; Schedule; Self Efficacy; Sleep; Sleep disturbances; Structure; alcohol misuse; alcohol rehabilitation; alcohol use disorder; alcoholism therapy; craving; drinking; experience; pattern perception; relapse prediction; research facility; social cognitive theory

Despite research establishing the relationship between sleep disturbances and alcohol use, there is no clear understanding or model for what occurs once individuals who seek inpatient alcoholism treatment are discharged from rehabilitation facilities and attempt to integrate back into their homes and communities. The purpose of this investigation will be to characterize sleep patterns, perceptions, and beliefs throughout the process of alcohol rehabilitation. The misuse of alcohol is a global public health concern that compromises both individual and societal wellbeing, resulting in an estimated 2.5 million deaths annually. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) distinguishes alcoholism by craving, loss of control, physical dependence, and tolerance (NIAAA, Alcohol Use Disorders). Outcome expectancies, behavioral capability, and self-efficacy beliefs are central constructs in the Social Cognitive Theory (Bandura, 1986) and are measured directly in this study using both quantitative and qualitative methods. A mixed methods approach is being used to study the following aims: a) to assess individuals' perceptions of and experiences with sleep during alcohol rehabilitation, b) to describe sleep patterns, perceptions, and beliefs among alcohol-dependent individuals throughout the transition from a clinical research facility providing rehabilitation treatment back to the community, c) to assess whether sleep-related beliefs and/or behavior of individuals are predictive of sleep quality or relapse to drinking, and d) to assess whether sleep quality predicts relapse. Sleep quality and duration are quantitatively assessed approximately one week prior to discharge from the inpatient facility and again 4-6 weeks post-discharge. A sub-set of participants are asked to wear actiwatches (accelerometers) to provide objective data on sleep throughout the transition from inpatient to outpatient. In addition to quantitative measures, qualitative semi-structured interviews were conducted with a subset of participants within a week of the scheduled discharge date and again four to six weeks post-discharge to assess perceptions of sleep during recovery. This proposed study will fill a gap in the literature by characterizing sleep throughout the rehabilitation process and ongoing maintenance of abstinence. The study is currently ongoing with 100 participants enrolled thus far. The qualitative portion of the study is completed and has been published. Recruitment for the quantitative portion of the study will continue until the proposed sample size is reached (N=219.)

尽管研究建立了睡眠障碍与饮酒之间的关系，但对于一旦寻求住院酒精中毒治疗的人的情况尚无明确的理解或模型。这项调查的目的是在整个酒精康复过程中表征睡眠方式，看法和信念。滥用酒精是全球公共卫生的关注，损害个人和社会福祉，每年估计死亡250万。美国国家酒精滥用与酒精中毒研究所（NIAAA）通过渴望，控制障碍，身体依赖和宽容（NIAAA，酒精使用障碍）来区分酒精中毒。结果期望，行为能力和自我效能感是社会认知理论中的核心构建体（Bandura，1986），并在本研究中直接使用定量和定性方法进行了测量。 A mixed methods approach is being used to study the following aims: a) to assess individuals' perceptions of and experiences with sleep during alcohol rehabilitation, b) to describe sleep patterns, perceptions, and beliefs among alcohol-dependent individuals throughout the transition from a clinical research facility providing rehabilitation treatment back to the community, c) to assess whether sleep-related beliefs and/or behavior of individuals are predictive of sleep quality or relapse to drinking, and d) to assess whether sleep quality预测复发。 睡眠质量和持续时间在从住院设施出院前大约一周，在入院后再次评估。要求参与者的子集佩戴ACTIWATCHES（加速度计），以在整个从住院到门诊病人的过渡过程中提供有关睡眠的客观数据。除量化措施外，定性半结构化访谈还在计划出院日期的一周内与一部分参与者进行，并在入院后四到六周再次进行，以评估恢复过程中对睡眠的看法。这项拟议的研究将通过在整个康复过程中表征睡眠和持续的节制维持，来填补文献中的空白。该研究目前正在进行中，到目前为止，有100名参与者参加了该研究。该研究的定性部分已完成并已发表。研究的定量部分招募将继续进行，直到达到建议的样本量为止（n = 219。）。