Clinical Trials Network: Mid-Atlantic Integrated Care Research Collaborative

临床试验网络：中大西洋综合护理研究合作组织

• 批准号: 9322099
• 负责人: ROBERT P SCHWARTZ
• 金额: $ 41.73万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9322099
• 关键词: Adolescent; Adoption; Adult; Advocate; Alcohol or Other Drugs use; Ancillary Study; Area; Assessment tool; Attention; Behavior Therapy; Caring; Clinical Trials; Clinical Trials Network; Communities; Community Health; Comprehensive Health Care; Conduct Clinical Trials; Counseling; Development; Drug abuse; Effectiveness; Elements; Enrollment; Evidence based practice; Evidence based treatment; Faculty; Foundations; Friends; Funding; Future; HIV; Health; Health Personnel; Health Services; Healthcare; Hospitals; Individual; Institution; Intervention; Knowledge; Lead; Leadership; Medical; Methodology; Methods; Mission; Modeling; Multi-Institutional Clinical Trial; National Institute of Drug Abuse; Network-based; Online Systems; Opioid; Participant; Patients; Pharmaceutical Preparations; Pharmacological Treatment; Pharmacotherapy; Population; Positioning Attribute; Primary Health Care; Provider; Public Health; Publications; Qualitative Research; Research; Research Infrastructure; Research Institute; Resources; Science; Scientific Advances and Accomplishments; Services; Site; Subgroup; Substance Use Disorder; Substance abuse problem; System; Testing; Tobacco Use Disorder; Tobacco smoking; Training; Triage; Universities; adolescent substance use; base; behavioral health; brief intervention; clinical research site; contingency management; evidence base; innovation; medical schools; novel strategies; programs; protocol development; research study; screening; screening and brief intervention; screening, brief intervention, referral, and treatment; substance abuse treatment; substance abuser; symposium; tool; treatment program

 DESCRIPTION: The overarching aim of the current application is to support the ability of the Mid-Atlantic Node to continue its participation in and enhance the scientific research mission of the NIDA Drug Abuse Treatment Clinical Trials Network (CTN) as the mission of the CTN continues to evolve. Our leadership of and participation in CTN research has been substantial and forms the basis for continued contributions. In the most recent funding period, we participated successfully in three CTN studies (0032, HIV Rapid Testing and Counseling; 0044, Web-Based Treatment of Substance Abusers; 0049, Hospital as the Opportunity for Patient Engagement), conducted two ancillary studies and enrolled over 600 participants. Currently, we are participating in two studies (0051; 0059) and providing national leadership for CTN 0059, a study to develop and validate a substance use screening and assessment tool for use in future CTN research. Our faculty offers expertise in a wide range of research areas including behavioral and pharmacological treatment of substance abuse, treatment of adolescents with substance use disorders, medications development, contingency management, screening, assessment and brief intervention, HIV treatment, tobacco smoking treatment, clinical trials methodology and qualitative research. We propose to continue supporting our well-established Node infrastructure that is needed to carry out the CTN research mission and to continue contributing the expertise and leadership available within the node. We envision and propose an innovative CTN research agenda with high public health importance that will identify and intervene with substance users found within medical care settings. New research on Screening and Brief Intervention will seek to identify subgroups that may benefit from this approach. Other proposed research will focus on linkage of patients with substance use at levels requiring more intensive intervention to treatment services. Patient Navigation will be examined as an approach to facilitating the care transitions across service delivery systems and motivating patients to engage in available services. This agenda builds on past CTN research and provides a visionary and feasible blueprint for cooperative multi-site research within the CTN and its affiliated medical care and drug treatment institutions. We have long maintained strong affiliations with an array of adult and adolescent community substance abuse treatment programs. Recent developments in health care have expanded the focus of our community involvement increasingly toward medical settings, including those with comprehensive care models that deliver both primary care and behavioral health services. We will continue to affiliate and engage a variety of hospital, community health and substance abuse treatment agencies that will serve as future resources for recruitment and conduct of CTN research. Overall, the Mid-Atlantic Node has made substantive contributions to the CTN that provide the foundation for its future involvement, and is well positioned to continue this involvement.

 描述：当前应用的总体目的是支持中大西洋节点继续参与并增强NIDA药物滥用治疗临床试验网络（CTN）的科学研究任务的能力，因为CTN的任务继续发展。我们对CTN研究的领导和参与是实质性的，构成了继续贡献的基础。在最近的资金期间，我们成功地参加了三项CTN研究（0032，HIV快速测试和咨询； 0044，基于Web的基于Web的药物滥用者； 0049，医院作为患者参与的机会）进行了两项辅助研究，并培养了600多名参与者。目前，我们正在参加两项研究（0051; 0059），并为CTN 0059提供国家领导，这是一项研究，旨在开发和验证物质使用筛查和评估工具，以在未来的CTN研究中使用。我们的教职员工在广泛的研究领域提供专业知识，包括对药物滥用的行为和药物治疗，对药物使用障碍的青少年的治疗，药物开发，应急管理，筛查，评估和简短干预，HIV治疗，烟草吸烟治疗，临床试验方法和定性研究。我们建议继续支持我们公认的节点基础架构，以执行CTN研究任务并继续贡献节点中可用的专业知识和领导力。我们设想并提出了具有很高公共健康重要性的创新CTN研究议程，可以识别并干预医疗服务中发现的物质用户。关于筛查和简短干预的新研究将寻求确定可能从这种方法中受益的亚组。其他建议的研究将重点介绍在需要对治疗服务进行更深入干预的水平上使用药物使用的患者的联系。患者导航将被检查为支持服务输送系统的护理过渡的一种方法，并激励患者参与可用的服务。该Agernda建立在过去的CTN研究的基础上，并为CTN及其会员医疗和药物治疗机构内的多站点研究提供了有远见且可行的蓝图。长期以来，我们一直保持着一系列成人和青少年社区滥用治疗计划的强大分支机构。医疗保健方面的最新发展扩大了我们社区参与的重点，包括那些提供初级保健和行为卫生服务的全面护理模型的医疗机构。我们将继续将各种医院，社区健康和药物滥用治疗机构与CTN研究的未来资源一起工作。总体而言，中大西洋节点为CTN做出了实质性贡献，为其未来的参与奠定了基础，并且可以很好地继续参与。