UT MD Anderson Cancer Center Network Lead Academic Participating Site (LAP)

UT MD 安德森癌症中心网络领导学术参与网站 (LAP)

• 批准号: 9024475
• 负责人: Cathy Eng
• 金额: $ 119.26万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-15 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9024475
• 关键词: Administrator; Adult; Advisory Committees; Authorship; Blood specimen; Cancer Center; Caring; Clinical; Clinical Research; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Network; Communication; Data; Data Quality; Development; Diagnostic Imaging; Discipline; Enrollment; Ensure; Faculty; Funding; General Hospitals; Goals; Grant; Group Meetings; Health; Image; Indigent; Institution; Institutional Review Boards; Lead; Leadership; Malignant Neoplasms; Medical Oncology; Mentors; Mentorship; Minority; Mission; National Clinical Trials Network; Operative Surgical Procedures; Participant; Pathology; Patients; Phase; Play; Principal Investigator; Protocols documentation; Publications; Radiation Oncology; Rare Diseases; Reporting; Research Design; Research Personnel; Resolution; Role; Services; Site; Surgical Oncology; Texas; Therapeutic Clinical Trial; Tissues; Training; Translational Research; Underinsured; Uninsured; Work; anticancer research; cancer therapy; education research; experience; faculty research; innovation; member; multidisciplinary; novel; oncology; operation; programs; protocol development; skills; success

DESCRIPTION (provided by applicant): Over the past 8 years, MD Anderson has made significant contributions to cancer clinical cooperative group trials, including robust accrual, scientific and administrative leadership, and mentoring young faculty to participate in and lead these important national trials. These attributes will be applied to the emerging National Clinical Trial Network (NCTN) with even greater emphasis through this Network Lead Academic Participant (LAP) grant, with the following overall aims: Aim 1) To provide robust participation in and accrual to Network group clinical trials targeting a broad range of adult patients with common as well as rare cancers; Aim 2) To promote best practices in the conduct of NCTN-sponsored clinical research and ensure high quality and timely submission of clinical trial-related data and materials as required by specific protocols; Aim 3) To provide scientific and administrative leadership within affiliated Network Groups, including protocol development, publication authorship, participation in Network committees / NCI Central IRB (CIRB), and attendance at Network Group meetings; and Aim 4) To mentor junior faculty, research personnel, and trainees in the leadership, conduct, analysis, and reporting of NCTN and other clinical trials. This LAP utilizes a Multiple Principal Investigator (PI) Plan to apply the demonstrated and complementary cooperative group leadership skills and expertise of 3 investigators: Dr. Cathy Eng, Dr. Kelly Hunt, and Dr. Ritsuko Komaki. In addition, investigators representing the disciplines of pathology, diagnostic imaging, gynecological oncology, surgery, and translational research will play key roles In cooperative group trial conduct and mentorship of young faculty. Oversight of trial accrual and data quality, fund management, centralized communications, and administrative support will be coordinated through the LAP Operations Center under the leadership of an experienced Program Administrator. An Executive Committee will ensure timely inter-Network group communications, effective study prioritizations, review and resolution of any accrual obstacles or data quality issues, and identification of junior facult across the institution as candidates for mentorship and/or leadership roles in Network clinical trials or committees.

描述（由申请人提供）：在过去的8年中，MD Anderson为癌症临床合作小组试验做出了重大贡献，包括健壮的应计，科学和行政领导，并指导年轻的教职员工参与并领导这些重要的国家试验。这些属性将应用于新兴的国家临床 试验网络（NCTN）通过该网络领导学术参与者（LAP）赠款更加重视，并具有以下总体目的：目标1） 并应为针对广泛的常见和罕见癌症患者的网络组临床试验累计；目标2）在进行NCTN赞助的临床研究中促进最佳实践，并确保高质量和及时提交与临床试验有关的 根据特定协议要求的数据和材料；目标3）在附属网络组中提供科学和行政领导，包括协议开发，出版作者身份，参加网络委员会 / NCI中央IRB（CIRB）（CIRB）以及参加网络小组会议；和目标4）指导初级教师，研究人员和学员的领导，行为，分析和报告NCTN和其他临床试验。这圈利用多个首席研究员（PI）计划应用3名调查人员的演示和补充合作团体领导技能和专业知识：Cathy Eng博士，Kelly Hunt博士和Ritsuko Komaki博士。此外，代表病理学学科，诊断成像，妇科肿瘤学，手术和翻译研究学科的研究人员将在合作小组试验和年轻教师的指导中发挥关键作用。在经验丰富的计划管理员的领导下，将通过LAP运营中心协调审判应计和数据质量，基金管理，集中式沟通和行政支持的监督。执行委员会将确保及时网络间集团的沟通，有效的研究优先级，审查和解决任何应计障碍或数据质量问题，并确定该机构中的初级技术作为指导和/或领导力在网络临床试验中的候选人和/或领导职务委员会。