University of New Mexico Cancer Center Support Grant

新墨西哥大学癌症中心支持补助金

基本信息

批准号：
9292598
负责人：
CHERYL LYNN WILLMAN
金额：
$ 12.35万
依托单位：
UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-26 至 2020-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9292598
关键词：
Address Adolescent and Young Adult Advisory Committees Aftercare American Indians Area Behavior Therapy Behavioral Bone Marrow Stem Cell Transplantation Cancer Biology Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Cancer Control Research Cancer Control Research Program Cancer Research Project Cancer Survivorship Catchment Area Centers for Disease Control and Prevention (U.S.)Cervical Characteristics Clinic Clinical Clinical Informatics Clinical Research Clinical Sciences Clinical Trials Network Collaborations Colorectal Cancer Communities Community Networks Comprehensive Cancer Center Development Diagnosis Diagnostic Direct Costs Doctor of Philosophy Early Diagnosis Endometrial Carcinoma Epigenetic Process Evaluation Faculty Fostering Funding Genetic Genomics Goals Health Health Professional Health system Healthcare Systems Hispanics Human Papilloma Virus Vaccination Improve Access Incidence Institutes Institution Interdisciplinary Study Intervention Intervention Studies Laboratories Latino Life Style Malignant Neoplasms Malignant neoplasm of lung Mentors Mexican Mission Modeling Molecular Epidemiology Morbidity - disease rate National Cancer Institute New Mexico Not Hispanic or Latino Oncologist Oncology Group Outcome Pattern Peer Review Pharmacology Phase Physicians Population Population Sciences Prevention Prevention strategy Primary carcinoma of the liver cells Provider Publications Race Recruitment Activity Registries Research Research Institute Research Personnel Research Support Research Training Resource Sharing Resources Risk Risk Reduction Schools Science Scientific Advances and Accomplishments Scientist Signal Transduction Social Identification Surveillance Program Technology Testing Therapeutic Therapeutic Clinical Trial Therapeutic Intervention Training Training Programs Training and Education Translating Translations Treatment outcome Tribes Underrepresented Minority Underserved Population United States Indian Health Service Universities Work anticancer research base behavior measurement cancer care cancer clinical trial cancer genetics cancer health disparity cancer risk cancer therapy care delivery cervical cancer prevention clinical care community intervention cooking design education research gene environment interaction graduate student improved laboratory facility malignant breast neoplasm medically underserved melanoma member mortality mortality disparity neuro-oncology novel outreach program programs ranpirnase research facility respiratory screening social socioeconomics survivorship targeted delivery telehealth tumor undergraduate student working group

项目摘要

DESCRIPTION (provided by applicant): The Cancer Control (CaC) Research Program is a newly restructured transdisciplinary program that serves as the hub for cancer control and population science research within the University of New Mexico Cancer Center (UNMCC) and the State of New Mexico (NM), our catchment area. The Program's overall goal is to reduce cancer incidence, morbidity, and mortality, particularly in the unique multiethnic and underserved populations of NM. Disparities research is a cross-cutting theme that fosters scientific focus and synergy across the research areas. Through vigorous strategic program planning and evaluation, recruitment of 9 new investigators to enhance expertise in molecular epidemiology and behavioral/community intervention, and guidance of the UNMCC External Advisory Committee, the CaC Program is now focused on three areas of cancer research: 1) Risk Prediction and Risk Reduction; 2) Screening; and 3) Post-Diagnosis Outcomes and Survivorship. Unique scientific strengths include research addressing disparities (geographic, race/ethnic, socioeconomic, medically underserved), particularly in etiologic, outcome, and intervention studies in Hispanics. By drawing on established and new partnerships, the Program is also building research that addresses American Indian cancer disparities and priorities identified by NM Tribes, Pueblos, and Indian Nations. Major scientific accomplishments in Risk Prediction and Risk Reduction include the identification of social, lifestyle, and genetic factors associated with lung cancer risk; gene-environment interactions in melanoma risk; and development and dissemination of a novel telehealth strategy for the prevention of hepatocellular cancer. In Screening, members have developed a statewide surveillance program of screening and diagnosis for cervical pre-cancer and cancer that informs real- world cervical cancer prevention through human papilloma virus (HPV) vaccination, screening practice and outcomes. Members have also identified barriers to use of early detection tests in colorectal cancer and have developed strategies to overcome these barriers to improve screening in underserved populations. In Post- Diagnosis Outcomes and Survivorship, members have identified factors that contribute to disparities in post- treatment outcomes and survivorship in endometrial and breast cancer and are developing interventions. Led by Linda Cook, Ph.D. and Anita Kinney, Ph.D., RN, the CaC Program is comprised of 28 members (19 full and 9 associate) from 7 UNM schools and departments, the Lovelace Respiratory Institute, and the Indian Health Service Unit of the Centers for Disease Control whose work is supported by $19,276,863 million in annual direct cost funding, of which $15,429,911 million is peer-reviewed and $3,137,820 million is from NCI as of 9/1/2014. The discoveries made in this Program have resulted 294 publications, of which 19% are intra-programmatic collaborations and 16% are inter-programmatic collaborations; with a total UNMCC and external collaborative publication level of 30% and 80%, respectively.

描述（由适用提供）：癌症控制（CAC）研究计划是一项新修复的跨学科计划，在新墨西哥大学癌症中心（UNMCC）和新墨西哥州（NM）（NM）（我们的集水区）中充当癌症控制和人口科学研究的枢纽。该计划的总体目标是降低癌症的发病率，发病率和死亡率，特别是在NM的独特多种族和服务不足的人群中。差异研究是一个横切主题，它促进了整个研究领域的科学重点和协同作用。通过有力的战略计划计划和评估，招募9名新研究人员，以增强分子流行病学和行为/社区干预方面的专业知识，以及UNMCC外部咨询委员会的指导，CAC计划现在侧重于癌症研究的三个领域：1）风险预测和风险降低； 2）筛选； 3）诊断后的结果和生存。独特的科学优势包括解决差异的研究（地理，种族/种族，社会经济，医疗服务不足），尤其是在西班牙裔的病因，结果和干预研究中。通过利用已建立和新的合作伙伴关系，该计划还正在建立研究，该研究涉及NM部落，普韦布洛斯和印度国家确定的美洲印第安癌症分配和优先事项。风险预测和降低风险的主要科学成就包括确定与肺癌风险相关的社会，生活方式和遗传因素；黑色素瘤风险中的基因环境相互作用；以及针对预防肝癌的新型远程医疗策略的发展和传播。在筛查中，成员已经制定了一项全州筛查和诊断症的监视计划，用于宫颈前癌和癌症，该计划通过人类乳头状瘤病毒（HPV）疫苗，筛查实践和结果来告知现实世界中的宫颈癌预防。成员还确定了在有色癌症中使用早期检测测试的障碍，并制定了克服这些障碍以改善服务不足人群筛查的策略。在诊断后的结局和生存期间，成员已经确定了导致治疗后结果和子宫内膜和乳腺癌生存差异的因素，并且正在发展干预措施。由Linda Cook博士领导。和RN的Anita Kinney博士，CAC计划由28名成员（19名和9个副部门）组成，来自7个UNM学校和部门，Lovelace呼吸研究所和疾病控制中心的印度卫生服务中心，其工作由每年的导演成本为19,276300万美元，其中包括19,276,8.63亿美元，其中包括15,911亿美元的pe。截至2014年9月1日，NCI $ 3,137,8.2亿美元。该计划中提出的发现产生了294个出版物，其中19％是策略内合作，有16％是程序间合作。总共汇率和外部协作出版物级别分别为30％和80％。