Mayo Comprehensive Cancer Center Grant (MICEO Supp) - Impact of Multi-Channel Communication Campaigns on Cancer Prevention, Control and Survivorship (CaPCaS) in Black, Hispanic, and Rural Populations

梅奥综合癌症中心拨款 (MICEO Supp) - 多渠道沟通活动对黑人、西班牙裔和农村人口癌症预防、控制和生存 (CaPCaS) 的影响

• 批准号: 10889628
• 负责人: CHERYL LYNN WILLMAN
• 金额: $ 20万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10889628
• 关键词: Administrative Supplement; Adoption; Advocate; Arizona; Attitude; Awareness; Behavior; Behavioral; Black Populations; Breast; Cancer Advocacy; Cancer Center Support Grant; Cancer Death Rates; Catchment Area; Clinic; Clinical Trials; Colorectal; Colorectal Cancer; Communication; Communities; Community Health; Community Outreach; Comprehensive Cancer Center; Continuity of Patient Care; Death Rate; Education; Florida; General Population; Geography; Goals; Grant; Health; Health Educators; Health Professional; Health system; Hispanic; Hispanic Populations; Intention; Knowledge; Life Style; Lung; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Malignant neoplasm of prostate; Midwestern United States; Pancreas; Population; Prevention; Preventive; Prostate; Public Health; Research Personnel; Rural Population; Scientist; Site; Survivors; Target Populations; Training; aged; black men; cancer care; cancer health disparity; cancer prevention; community engagement; evidence base; genetic testing; handbook; health communication; health equity; implementation science; improved; innovation; literacy; mortality; programs; response; screening; survivorship

ABSTRACT This application is being submitted by the Mayo Clinic Comprehensive Cancer Center (MCCCC) in response to the “Administrative Supplements for the NCI P30 Cancer Center Support Grants for Multi-Channel Communication Campaigns”. The MCCCC community outreach and engagement activities are led by the MCCCC Community Outreach & Engagement (COE) Office and Programs in three MCCCC catchment areas (CAs), including Arizona (AZ), Florida (FL) and the Midwest/Mayo Clinic Health Systems (MCHS). Although our 3-site catchment areas (CAs) are unique communities, the top cancers at each site are lung, breast, prostate, colorectal and pancreas. However, cancer disparities are uniquely different for the priority populations. In AZ CA, the targeted cancers are colorectal cancer (CRC) and liver cancer. Hispanics are twice likely to die from liver cancer compared to NH Whites. Although the CRC mortality rate is similar for both Hispanic and NH Whites, the CRC mortality rate for AZ CA Hispanics is elevated compared to US Hispanics. In FL CA, the targeted cancer is prostate cancer (CaP) in NH Black men. CaP leads cancer mortality among NH Blacks in the FL CA. Black men are twice as likely to die from CaP. The CaP death rate for Black men in FL is also elevated compared to the death rate for US Black men. In the Midwest/MCHS CA, the targeted cancers are lung, prostate, and colorectal cancers. These cancers are three of the top five cancers in the CA. The proposed supplement project focuses on Track 2, targeting the general population aged 30 years and above. Multi-channel communication campaigns will be delivered by Community Health Educators (CHEs) across the cancer care continuum and tailored to each of the MCCCC CAs. The primary goal of the supplement is to assess the impact of multi-channel communication campaigns targeting Black, Hispanic, and Rural populations on cancer prevention, control and survivorship (CaPCaS). This goal will be achieved through three specific aims: (1) Using the MCCCC Cancer Advocacy Handbook, train 15 (5 at each site) cancer advocates/survivors to lead the CaPCaS communication campaigns as CHEs, focusing primarily on improving cancer health and clinical trials literacy, increasing awareness about cancer prevention, screenings and genetic testing, and promoting preventive lifestyle behaviors; Adapt and implement evidence-based and innovative, culturally tailored, multi-channel educational communication campaigns tailored to Black men in FL CA, Hispanics in AZ CA and rural populations in the Midwest/MCHS geographies; and Evaluate the impact of the CaPCaS campaigns relative to increasing CaPCaS-related knowledge, attitudes, behavioral intention and adoption of prevention behavior.The academic-community team assembled for this project is comprised of health equity scientists, behavioral scientists (including implementation science researchers), clinician scientists, and public health professionals with significant expertise in health communications. (2) (3)

抽象的 该申请由Mayo诊所综合癌症中心（MCCCC）提交 对“ NCI P30癌症中心的管理补品支持多通道的赠款”的回应 沟通运动”。MCCCC社区推广和参与活动由 MCCCC社区外展与参与（COE）办公室和计划在三个MCCCC集水区 （CAS），包括亚利桑那州（AZ），佛罗里达州（FL）和中西部/梅奥诊所卫生系统（MCHS）。虽然我们的 3个站点集水区（CAS）是独特的社区，每个地点的顶级癌症是肺，乳房，前列腺，前列腺， 结直肠和胰腺。但是，优先人群的癌症差异是唯一的不同。在AZ CA，有针对性的癌症是结直肠癌（CRC）和肝癌。西班牙裔可能死于 与NH白人相比，肝癌。尽管西班牙裔和NH白人的CRC死亡率相似，但 与我们西班牙裔人相比，AZ CA西班牙裔的CRC死亡率升高。在FL CA，目标癌 是NH黑人的前列腺癌（CAP）。 CAP导致佛罗里达州NH黑人的癌症死亡率。黑色的 男人死于帽子的可能性是两倍。与 我们黑人的死亡率。在中西部/MCHS CA中，目标癌症是肺，前列腺和 结直肠癌。这些癌症是CA的前五名癌症中的三种。 拟议的补充项目着重于轨道2，针对30岁的普通人群 及以上。社区健康教育者（CHES）将发表多渠道沟通活动 在整个癌症的整个护理中，继续为MCCCC CAS量身定制。补充的主要目标 是为了评估针对黑人，西班牙裔和农村的多渠道沟通运动的影响 预防癌症，控制和生存的人群（CAPCAS）。这个目标将通过三个 具体目的： （1） 使用MCCCC癌症倡导手册，训练15（每个站点5）癌症 倡导者/幸存者以CHE为领导CAPCAS沟通运动，主要专注于改善 癌症健康和临床试验素养，提高人们对预防癌症，筛查和遗传的认识 测试并促进预防性生活方式行为；适应并实施循证和创新， 针对佛罗里达州的黑人量身定制的文化量身定制的多渠道教育交流活动， 亚利桑那州CA的西班牙裔和中西部/MCHS地区的粗糙人口；并评估 CAPCAS运动相对于增加与CAPCA相关的知识，吸引力，行为意图和 采用预防行为。为该项目组成的学术社区团队已完成健康 股票科学家，行为科学家（包括实施科学研究人员），临床科学家和 具有重要专业知识的公共卫生专业人员。 （2） （3）

项目成果

Prevalence of BCL-2/J(H) Translocation in Healthy African Americans.

健康非洲裔美国人中 BCL-2/J(H) 易位的患病率。

• DOI: 10.1007/s00277-016-2842-4
• 发表时间: 2017
• 期刊: Annals of hematology
• 影响因子: 3.5
• 作者: Colon-Otero,Gerardo;VanWier,ScottA;Ahmann,GregJ;Braggio,Esteban;Albertie,MonicaL;Weis,JenniferA;Ailawadhi,Sikander;Cerhan,JamesR;Vishnu,Prakash;Jorgensen,MatthewS;Foran,JamesM;Thomas,ColleenS;Fonseca,Rafael
• 通讯作者: Fonseca,Rafael

Prediagnostic alcohol consumption and colorectal cancer survival: The Colon Cancer Family Registry.

• DOI: 10.1002/cncr.30446
• 发表时间: 2017-05-15
• 期刊: Cancer
• 影响因子: 6.2
• 作者: Phipps AI;Robinson JR;Campbell PT;Win AK;Figueiredo JC;Lindor NM;Newcomb PA
• 通讯作者: Newcomb PA

Folate receptor alpha expression associates with improved disease-free survival in triple negative breast cancer patients.

叶酸受体α表达与三阴性乳腺癌患者无病生存率的改善相关。

• DOI: 10.1038/s41523-020-0147-1
• 发表时间: 2020
• 期刊: NPJ breast cancer
• 影响因子: 5.9
• 作者: Norton,Nadine;Youssef,Bahaaeldin;Hillman,DavidW;Nassar,Aziza;Geiger,XochiquetzalJ;Necela,BrianM;Liu,Heshan;Ruddy,KathrynJ;Polley,Mei-YinC;Ingle,JamesN;Couch,FergusJ;Perez,EdithA;Liu,MinettaC;Carter,JodiM;Leon-Ferre,R
• 通讯作者: Leon-Ferre,R

Chronic lymphocytic leukemia (CLL) with Reed-Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter?

• DOI: 10.1038/s41408-022-00616-6
• 发表时间: 2022-01-28
• 期刊: Blood cancer journal
• 影响因子: 12.8
• 作者: King RL;Gupta A;Kurtin PJ;Ding W;Call TG;Rabe KG;Kenderian SS;Leis JF;Wang Y;Schwager SM;Slager SL;Kay NE;Koehler A;Ansell SM;Inwards DJ;Habermann TM;Shi M;Hanson CA;Howard MT;Parikh SA
• 通讯作者: Parikh SA

Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota.

• DOI: 10.1038/s41408-022-00659-9
• 发表时间: 2022-04-19
• 期刊: BLOOD CANCER JOURNAL
• 影响因子: 12.8
• 作者: Kleinstern, Geffen;Larson, Dirk R.;Allmer, Cristine;Norman, Aaron D.;Muntifering, Grace;Sinnwell, Jason;Visram, Alissa;Rajkumar, Vincent;Dispenzieri, Angela;Kyle, Robert A.;Slager, Susan L.;Kumar, Shaji;Vachon, Celine M.
• 通讯作者: Vachon, Celine M.