Imaging Core

成像核心

• 批准号: 9087283
• 负责人: GEOFFREY M BOVE
• 金额: $ 14.46万
• 依托单位: UNIVERSITY OF NEW ENGLAND
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2017-06-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9087283
• 关键词: Address; Affect; Biological; Centers of Research Excellence; Confocal Microscopy; Electron Microscopy; Histology; Image; Inflammation; Lead; Manuscripts; Methodology; Methods; Musculoskeletal; Neurons; Nociception; Pain; Publishing; Recruitment Activity; Research Personnel; Sampling; Scientist; Sensory; Structure; Technical Expertise; Training; experience; instrumentation; morphometry; relating to nervous system; tissue processing

The Histology and Imaging Core will provide technical expertise, training, and state-of-the-art instrumentation for the processing of tissue and the analysis of biological samples, including confocal microscopy and stereology. In the previous submission, we did not have a Director for the Histology and Imaging Core and instead proposed to recruit a senior level scientist who could lead this Core. We have been successful in this recruitment effort with the addition of Dr Geoffrey Bove, a pain researcher with a primary focus on examining how inflammation affects primary afferent nociceptive neurons. Dr Bove has extensive experience in histology, image acquisition, histomorphology of neural and musculoskeletal structures, and immunofluorescent morphometry. He has published numerous manuscripts using histological and immunohistological methods, as well as using electron microscopy. Dr Bove has also developed immunoquantification methods using stereological and non-stereologicat approaches. In addition, we have recruited Dr Willis, a COBRE Project Leader with expertise in confocal and electron microscopy who will serve as co-Director The Histology and Imaging Core Directors will advise investigators on the best approach to address their questions, provide training in methodology and instrumentation, and to supervise the Core manager/technician.

组织学和成像核心将提供技术专长，培训和 用于加工组织的最新仪器和生物样品分析，包括 共聚焦显微镜和立体学。在上一篇文章中，我们没有组织学主任 并提出成像核心，而是建议招募一个可以领导这一核心的高级科学家。我们有 在这项招聘工作中取得了成功，加入了乔弗里·鲍夫（Geoffrey Bove）博士，他是一名痛苦的研究人员 主要的重点是检查炎症如何影响主要传入伤害神经元。 Bove博士有 在组织学，图像获取，神经和肌肉骨骼的组织学方面的丰富经验 结构和免疫荧光形态计量学。他使用组织学发表了许多手稿 和免疫组织学方法以及使用电子显微镜。 Bove博士也开发了 使用立体和非疾病方法的免疫化方法。此外，我们还有 招募了Willis博士，Willis博士是一名具有共焦和电子显微镜专业知识的鞋底项目负责人 作为联合导演，组织学和成像核心主管将向调查人员提供有关最佳方法的建议 解决他们的问题，提供方法和仪器方面的培训并监督核心 经理/技术人员。