Core A: Administrative Core

核心A：行政核心

• 批准号: 10581510
• 负责人: John M Sedivy
• 金额: $ 4.16万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10581510
• 关键词: Age; Aging; Alzheimer' s Disease; Applications Grants; Attention; Biology; Cell Line; Central Nervous System; Chronic; Collaborations; Communication; Communities; Complementary DNA; Consensus; Cytoplasm; DNA Damage; Data Set; Databases; Dementia; Deposition; Development; Disease; Ensure; Evaluation Research; Genome; Goals; Host Defense Mechanism; Inflammaging; Inflammation; Information Dissemination; Innate Immune System; Insertional Mutagenesis; Institution; Interferon Type I; Joints; L1 Elements; Lead; Leadership; Mediation; Mentors; Modeling; Molecular; Monitor; Nerve Degeneration; Neurodegenerative Disorders; Nucleosides; Process; Progress Reports; Protocols documentation; Publications; Reagent; Recommendation; Regulation; Repetitive Sequence; Reporter; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resolution; Resource Sharing; Resources; Retrotransposition; Retrotransposon; Reverse Transcriptase Inhibitors; Role; Services; Site; Sterility; Technology; Training; Transcript; United States National Institutes of Health; Writing; age related; conflict resolution; data submission; derepression; design; high standard; inhibitor therapy; meetings; member; mouse model; new technology; novel; programs; public database; recruit; response; tool; translational potential; videoconference

PROJECT SUMMARY (CORE A) The overall goals of the Administrative Core (Core A) are to provide scientific, programmatic and fiscal leader- ship, facilitate lines of communication between the different researchers involved in the PPG, maintain cohe- rence in the PPG’s overall and long-range goals, and ensure that resources resulting from the PPG will benefit the scientific community. Core A will thus provide the mechanisms to manage, evaluate, and evolve the four Research Projects and two Research Cores in the program. In the context of the above, the task of Core A will be the effective coordination of the activities of all the components, such as the selection and design of jointly used models and resources (cell lines, mouse models, transposon reporters, protocols, etc.), the development of new technologies and tools to more effectively promote the research goals, and enabling the scientific community access to the PPG’s resources, technologies, and databases. The following activities will also contribute to achieving these overall goals: 1) Core A will ensure that the administrative and financial requirements of the NIH and the participating institutions are met; 2) Core A will organize monthly videoconferences and annual face-to-face retreats; 3) Core A will be responsible for communications between the PPG and the NIH; 4) Core A will facilitate the submission of joint publications and, in collaboration with Core B, the deposition of high-throughput datasets into public databases; 5) Core A will establish the External Advisory Board (EAB) and organize the annual reviews of the PPG.

项目摘要（核心 A） 行政核心（核心 A）的总体目标是提供科学、计划和财政方面的领导—— 船，促进参与 PPG 的不同研究人员之间的沟通渠道，保持凝聚力 PPG 总体和长期目标的绩效，并确保 PPG 产生的资源将受益 因此，科学界将提供管理、评估和发展这四个方面的机制。 该计划中的研究项目和两个研究核心 在上述背景下，核心 A 的任务将是。 有效协调所有组成部分的活动，例如共同选择和设计 使用的模型和资源（细胞系、小鼠模型、转座子生产者、协议等）、开发 新技术和工具的使用，以更有效地促进研究目标，并使科学 社区访问 PPG 的资源、技术和数据库还将开展以下活动。 1) 核心 A 将确保行政和财务 满足 NIH 和参与机构的要求； 2) Core A 将每月组织一次； 3) 核心 A 将负责各成员之间的沟通； PPG 和 NIH；4) Core A 将与 Core 合作促进联合出版物的提交 B，将高通量数据集存入公共数据库； 5) 核心 A 将建立外部咨询； 董事会 (EAB) 并组织 PPG 的年度审查。