Immune System Development and Regulation

免疫系统的发育和调节

• 批准号: 8903781
• 负责人: Michael Paul Cancro
• 金额: $ 18.55万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8903781
• 关键词: Immune system; Regulation; Systems Development

DESCRIPTION (provided by applicant): This program requests 4 predoctoral positions for training in immune system development and regulation (ISDR). The program includes 26 trainers with expertise in the development and regulation of the immune system, who are a subset of the Immunology Graduate Group (IGG) at the University of Pennsylvania. This discipline-based training program has a >35-year record of outstanding training. The academic elements of the IGG curriculum form the core experiences for trainees in the ISDR program, and reflect a proven yet evolving mixture of coursework, laboratory rotations, research presentations, and thesis research. These are enriched by a large array of additional activities that foster scientific exchange and discussion, including ongoing activities such as our annual 2.5-day retreat, weekly colloquium, and weekly work-in-progress series, as well as an agreement that affords training with adjunct faculty on the NIH Bethesda campus. The assembled trainers for this grant have highly productive training records in the area of immune system development and regulation, as well as over $75M in annual research support to assure quality and continuity of the training experience. The breadth and strength of the assembled training faculty affords a diverse array of potential trainee mentors. The program has over 100 applicants annually, which are a subset of over 1,000 applicants to biomedical graduate studies at the University of Pennsylvania. The IGG program recruits between 8 to 12 PhD and 2 to 5 MD-PhD trainees per year, yielding a student body of ~60 students, and the ISDR supports a subset of the upper 15% of these. The ISDR focuses specifically on students/faculty whose research is directed towards understanding the development and regulation of the immune system and immune responses. In this regard, the ISDR fosters research training that bears directly on control and manipulation of the immune system in health and disease.

描述（由申请人提供）：该项目需要 4 个博士前职位，用于免疫系统发育和调节 (ISDR) 方面的培训。该计划包括 26 名在免疫系统发育和调节方面具有专业知识的培训师，他们是宾夕法尼亚大学免疫学研究生小组 (IGG) 的一部分。这一基于学科的培训计划拥有超过 35 年的杰出培训记录。 IGG 课程的学术要素构成了 ISDR 项目学员的核心经验，并反映了课程作业、实验室轮换、研究演示和论文研究的经过验证且不断发展的组合。这些活动还通过大量促进科学交流和讨论的额外活动得以丰富，包括正在进行的活动，例如我们每年 2.5 天的静修会、每周研讨会和每周正在进行的工作系列，以及提供培训的协议NIH 贝塞斯达校区的兼职教师。本次资助的培训师在免疫系统发育和调节领域拥有高效的培训记录，以及超过 7500 万美元的年度研究支持，以确保培训体验的质量和连续性。培训师资队伍的广度和实力为各种潜在的实习导师提供了机会。该项目每年有 100 多名申请者，这是宾夕法尼亚大学生物医学研究生课程 1,000 多名申请者的一部分。 IGG 项目每年招收 8 至 12 名博士生和 2 至 5 名医学博士-博士生，学生总数约为 60 名，ISDR 支持其中前 15% 的一部分。 ISDR 特别关注学生/教师，他们的研究旨在了解免疫系统和免疫反应的发展和调节。在这方面，ISDR 促进了与健康和疾病中免疫系统的控制和操纵直接相关的研究培训。