Implementation Science and Health Outcomes Core

实施科学与健康成果核心

• 批准号: 10090641
• 负责人: Denis Nash
• 金额: $ 23.17万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-30 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10090641
• 关键词: AIDS clinical trial group; AIDS prevention; AIDS/HIV problem; Address; Adherence; Affinity; Africa South of the Sahara; Area; Biomedical Technology; Caring; Cities; Clinical Research; Clinical effectiveness; Collaborations; Community Health Systems; Consultations; Continuity of Patient Care; Diagnosis; Discipline; Doctor of Medicine; Doctor of Philosophy; Effectiveness; Epidemic; Epidemiologist; Epidemiology; Evidence based intervention; Fostering; Funding; Gap Junctions; Geographic Locations; HIV; HIV diagnosis; Health; Health Policy; Healthcare Systems; Institutes; Intervention; Link; Mental Health; Mental disorders; Mentors; Modeling; New York; Outcome; Policies; Policy Analysis; Policy Maker; Population Analysis; Prevention; Prophylactic treatment; Psychiatrist; Psychiatry; Public Health; Research; Research Design; Research Infrastructure; Research Personnel; Science; Scientist; Structure; Testing; Time; Translations; United States National Institutes of Health; Universities; Viral; Vulnerable Populations; behavioral study; behavioral/social science; career; clinical center; comorbidity; economic evaluation; effectiveness implementation study; effectiveness research; evidence base; health disparity; implementation intervention; implementation research; implementation science; improved; innovation; interdisciplinary collaboration; interest; low and middle-income countries; novel strategies; population based; population health; practice setting; pre-exposure prophylaxis; prevent; programs; research study; scale up; screening; substance use; uptake; working group

Although millions of lives have been saved by new biomedical technologies and expansion of prevention and treatment in low- and middle-income countries, many vulnerable people – including in the US – are not benefiting from these advances. Implementation science (IS) research can maximize public health impact by addressing suboptimal implementation of evidence-based strategies; identifying ways in which health care systems and policies fail to adequately address the HIV prevention and care continua; and identifying population-based strategies to improve HIV outcomes in the US and globally. The Implementation Science and Health Outcomes (ISHO) Core will address the HIV Center's overall theme by catalyzing innovative IS research that identifies and tests strategies to optimize “real-world” uptake and impact of effective HIV prevention and care continua interventions at scale. The Core has three Specific Aims: (1) to stimulate new IS research and collaborations to improve key outcomes along the HIV prevention and care continua; (2) to advance new IS research to prevent or reduce HIV-related health disparities that are driven by suboptimal intervention implementation or by psychiatric and other comorbidities; and (3) to promote the use of health policy analysis, policy modeling, and economic evaluation to bridge the evidence-practice and evidence-policy gaps that drive suboptimal population-based implementation and disparities. The ISHO Core will accomplish its Aims through functions that include (1) providing expert consultation to HIV Center researchers on conducting IS research that (a) both tests new approaches to improve HIV-related programmatic outcomes and assesses causes of successful and un-successful implementation of interventions and policies at scale, and (b) incorporates the perspectives of policy translation, policy modeling, and economic evaluation into their research; (2) developing Scientific Working Groups to provide structured and focused guidance to (and collaboration with) Center investigators interested in or embarking on IS through dynamic small groups organized around specific themes (e.g., PrEP implementation, psychiatric comorbidities); (3) facilitating access to linked networks for HIV Center investigators addressing IS-related research questions; and (4) sponsoring seminars to stimulate the use of IS approaches in research. The proposed Core Director, Denis Nash, Ph.D., is an epidemiologist and Director of the Institute for Implementation Science in Population Health (ISPH) at the City University of New York. Core Co-Director, Milton Wainberg, M.D., is a research psychiatrist at the New York State Psychiatric Institute and Columbia University Department of Psychiatry. Together they have extensive expertise in NIH-funded research and capacity building for HIV and mental health treatment and prevention. The Core brings together early stage, mid-career, and established investigators in the areas of IS, health-disparities, and economic evaluation with policy-makers and program implementers to provide an infrastructure for research collaboration.

尽管新的生物医学技术和扩大预防措施拯救了数百万人的生命 低收入和中等收入国家的治疗和治疗，许多弱势群体 — — 包括美国的 — — 并没有受到影响 受益于这些进步，实施科学（IS）研究可以通过以下方式最大限度地提高公共卫生影响。 解决基于证据的策略实施欠佳的问题；确定卫生保健的方式； 系统和政策未能充分解决艾滋病毒预防和护理问题； 以人口为基础的战略，以改善美国和全球的艾滋病毒结果。 和健康成果 (ISHO) 核心将通过促进创新 IS 来解决艾滋病毒中心的总体主题 研究确定和测试优化“现实世界”有效艾滋病毒的吸收和影响的策略 大规模的预防和护理连续干预措施具有三个具体目标：(1) 刺激新的信息系统。 研究和合作以改善艾滋病毒预防和护理连续性的关键成果（2） 新的 IS 研究旨在预防或减少由次优导致的与艾滋病毒相关的健康差异 实施干预措施或针对精神科和其他合并症；以及 (3) 促进健康的使用； 政策分析、政策建模和经济评估，以连接证据-实践和证据-政策 导致基于人口的实施欠佳和差异的差距。 ISHO 核心将通过以下职能实现其目标：(1) 向 HIV 中心研究人员进行的 IS 研究 (a) 均测试了改善 HIV 相关问题的新方法 规划成果并评估成功和不成功实施干预措施的原因 和大规模的政策，并且（b）纳入了政策转化、政策建模的观点，以及 对他们的研究进行经济评估；(2) 建立科学工作组，以提供结构化和 通过以下方式向对信息系统感兴趣或着手信息系统的中心调查人员提供集中指导（并与之合作）： 围绕特定主题（例如 PrEP 实施、精神病学 (3) 为艾滋病毒中心调查人员访问链接网络提供便利，以解决与伊斯兰国相关的问题 研究问题；(4) 主办研讨会以促进信息系统方法在研究中的应用。 拟议的核心主任丹尼斯·纳什博士是一名流行病学家兼研究所所长 纽约城市大学人口健康实施科学 (ISPH) 核心联合主任。 米尔顿·温伯格（Milton Wainberg），医学博士，纽约州精神病学研究所和哥伦比亚大学心理学研究人员 他们在 NIH 资助的研究和研究方面拥有广泛的专业知识。 艾滋病毒和心理健康治疗和预防的能力建设汇集了早期阶段、 职业中期，并在信息系统、健康差异和经济评估领域建立了调查员 政策制定者和计划实施者为研究合作提供基础设施。