Alterations and Renovations

改建和翻新

• 批准号: 10090987
• 负责人: Peter Stephen Steyger
• 金额: $ 12.78万
• 依托单位: CREIGHTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-05 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10090987
• 关键词: Acids; Air; Auditory; Auditory Brainstem Responses; Award; Centers of Research Excellence; Chemicals; Complex; Computers; Core Facility; Drug Delivery Systems; Duct (organ) structure; Environment; Equipment; Floor; Health Services Research; Hearing; Hearing Tests; Hospitals; Image; Institution; Laboratories; Light; Lighting; Medical center; Microscope; Modernization; Nebraska; Pharmaceutical Chemistry; Research; Research Personnel; Research Project Grants; Savings; Services; Side; Solid; System; Technology; Testing; Therapeutic; Translational Research; Universities; Visual; boys; chemical synthesis; drug discovery; exhaust; foot; hearing impairment; operation; otoacoustic emission

ALTERATION & RENOVATION Project Summary/Abstract The Translational Hearing Center (THC) has established two functional cores: The Drug Discovery & Delivery Core (DDDC) and Auditory & Vestibular Technology Core (AVTC) to promote and enhance translational research on therapeutics for hearing loss. Currently all core facilities and equipment are located in close proximity to or within the Creighton University Core Facilities in the Criss I/II/III building complex, with additional satellite AVTCs located in neighboring institutions: University of Nebraska Medical Center (UNMC) and Boys Town National Research Hospital (BTNRH). To further empower our services for the Research Project Leaders (RPLs) and Center Investigators, we plan to align our facilities with our strength by creating new laboratory spaces through renovation of existing laboratories within first year of the COBRE award. To facilitate efficient chemical synthesis and analysis and facilitate new advanced imaging, we seek to renovate medicinal chemistry laboratory Criss II 326 and a new space for auditory hearing test laboratory Criss I 304. With these renovation projects completed, THC will have new, centralized laboratories for each core. These can be easily further expanded and integrated into the Creighton University Core Facilities. These will significantly enhance our services outlined in our proposal.

改建与翻新 项目概要/摘要 转化听力中心 (THC) 建立了两个功能核心： 药物 发现和交付核心 (DDDC) 以及听觉和前庭技术核心 (AVTC) 促进和加强听力损失治疗的转化研究。目前所有核心 设施和设备位于克赖顿大学核心区附近或之内 Criss I/II/III 建筑群内的设施，以及额外的卫星 AVTC 位于 邻近机构：内布拉斯加大学医学中心 (UNMC) 和 Boys Town 国家研究医院 (BTNRH)。进一步增强我们为研究项目提供的服务 领导者（RPL）和中心研究人员，我们计划通过以下方式使我们的设施与我们的实力相一致： 在第一年内通过改造现有实验室来创建新的实验室空间 科布雷奖。促进高效的化学合成和分析，并促进新的 先进的成像，我们寻求翻新药物化学实验室 Criss II 326 和一个新的 听觉听力测试实验室 Criss I 304 的空间。随着这些改造项目的完成， THC 将为每个核心设立新的集中实验室。这些都可以很容易地进一步 扩建并整合到克赖顿大学核心设施中。这些将显着 加强我们提案中概述的服务。