The Health ePeople Resource for Mobilized Research

用于动员研究的 Health ePeople 资源

• 批准号: 9064457
• 负责人: GREGORY M MARCUS
• 金额: $ 198.75万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-30 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064457
• 关键词: 18 year old; Address; American Heart Association; Area; Award; Cardiovascular Diseases; Cardiovascular system; Cellular Phone; Characteristics; Clinical; Clinical Data; Clinical Research; Cohort Studies; Communities; Consent; Data; Data Base Management; Data Collection; Data Linkages; Data Sources; Databases; Development; Devices; Diet; Discipline; Electronic Health Record; Electronic Mail; Electronics; Emerging Technologies; Enrollment; Event; Foundations; Framingham Heart Study; Funding; Geographic Locations; Goals; Health; Health Resources; Institutional Review Boards; Internet; Investments; Lung; Methods; Modeling; Neurology; Obesity; Outcome; Participant; Patient Outcomes Assessments; Patients; Pattern; Physical activity; Population; Positioning Attribute; Principal Investigator; Privacy; Procedures; Protocols documentation; Randomized Controlled Trials; Recruitment Activity; Research; Research Infrastructure; Research Institute; Research Personnel; Resources; San Francisco; Security; Services; Surveys; System; Technology; Testing; Time; Transplantation; Urology; Validation; Water; Work; adjudicate; base; cardiovascular health; cohort; cost effective; data integration; data management; data sharing; design; digital; experience; flexibility; handheld mobile device; high standard; improved; industry partner; innovation; interest; mHealth; mobile application; novel; oncology; patient advocacy group; public health relevance; randomized trial; sensor; tool; user-friendly; volunteer

 DESCRIPTION (provided by applicant): We seek to create the Health ePeople Resource, a nimble, readily-accessible, and reliable infrastructure to conduct mHealth research. This effort will build on the current Health eHeart Study, an internet-based clinical research platform that has enrolled more than 20,000 engaged participants from around the world. Although initially developed to study cardiovascular disease, Health eHeart is in use by investigators from multiple fields, and helps us jumpstart many of the objectives set out in the current RFA. We have successfully implemented a user-friendly interface built to collect patient-reported outcomes, validated survey data, and integrations with multiple sensors, devices, and apps; we have an IRB approved system using modular electronic consenting; we have over 20,000 deeply involved participants interested in contributing to mHealth research; we have developed ways for external investigators to utilize and enroll their own participants in a customizable fashion; we have developed a study management portal (including a real-time dashboard and participant characteristic- based filtering system) and a flexible messaging system that can be utilized by external investigators; we have built a database and data management system constructed to adhere to the highest standards of privacy, security, and reliability; and we have iterated and adapted the platform to take advantage of emerging technology and cutting-edge methods. Building from these strengths, we are ready to fully leverage the opportunities afforded by this award, transforming the Health eHeart Study into a general Health ePeople Resource. The primary goal of Health ePeople will be to provide a resource that enables convenient and efficient mHealth research. The Resource will help investigators collect mHealth data via integration with sensors, devices, and apps, deliver online surveys, connect with external data sources including electronic health records, and use novel methods for ascertaining and adjudicating clinical outcome events. The Resource will support utilization of patients already enrolled in the Health ePeople Cohort or "co-enrollment" (and data linkage) of participants recruited externally. We will utilize our experience engaging and consenting more than 20,000 patients to grow and expand a world-wide cohort of participants (the Health ePeople Cohort) interested in contributing to mHealth research. The platform will support development and validation of apps, including randomized controlled trials. This effort will leverage our experience working with foundations and patient-advocacy groups as well as our position in PCORnet and the resultant collaborative relationships with multiple large PCORI-funded Clinical Data Research Networks that can provide access to hundreds of millions of patients and their electronic health records. We will develop the technology, procedures and governance to support rapid access to the Health ePeople cohort for research, data sharing, analyses and integration with external databases. Finally, we will develop and test various models for providing access to Health ePeople resources and services that will assure financial sustainability beyond the award period.

 描述（由申请人证明）：我们寻求创建动画，可靠的基础架构的动画资源超过20,000个在世界各地使用的人都在使用。与传感器和应用程序的集成；我们使用模块化的电子内容；系统可以通过扩展器来构建数据库和数据管理，以确保安全性和可靠性；从这些优势中，我们准备充分利用该奖项提供的机会，将健康性研究转变为一般的健康状况资源。将帮助调查人员与传感器，设备和应用程序收集MHealth数据集成，并与包括电子健康记录在内的三元数据源连接，并使用新颖的方法来确定和判断性结果事件。 - 招募参与者的（以及数据链接）。与PCORN的ADVOCACACATIO群体以及由多个大型临床数据研究网络的合作关系，可以为数百万的Ients和ThelectRonic Health提供访问。卫生局长霍特（Hort）研究，数据共享，分析和与外部数据库进行集成。