HD2A Research Adoption Support Center (RASC)

HD2A 研究采用支持中心 (RASC)

基本信息

批准号：
10596435
负责人：
WILLIAM C BECKER
金额：
$ 331.1万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-30 至 2027-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10596435
关键词：
Address Adoption Attitude Awareness Case Study Catalogs Collaborations Communities Complex Consensus Data Development Dimensions Dissemination and Implementation Economics Ensure Epidemic Evaluation Research Evidence based intervention Evidence based practice Faculty Goals Harm Reduction Health Human Intervention Intervention Studies Investments Knowledge Leadership Learning Life Measurement Measures Methodology Methods Modeling Monitor National Institute of Drug Abuse Opiate Addiction Opioid Outcome Pain Pain management Persons Policies Prevention Prevention strategy Public Health Publications Records Research Research Design Research Personnel Research Project Grants Resources Savings Scientist Services Site Specific qualifier value Standardization Stimulant Substance Use Disorder System Technical Expertise Terminology Theoretical model Thinking Translating Translational Research United States National Institutes of Health Ursidae Family addiction base community living data harmonization data infrastructure design dissemination research dissemination science evidence base experience formative assessment health care availability implementation evaluation implementation research implementation science implementation strategy implementation study implementation tool improved innovation knowledge base online resource opioid epidemic opioid mortality opioid use disorder overdose death overdose prevention prevent program dissemination programs provider intervention real world application research study resource guides response service delivery social capital social stigma stem substance use substance use prevention symposium translational barrier

项目摘要

OVERALL: PROJECT SUMMARY/ABSTRACT In response to the National Institutes of Health RFA-DA-22-050, we herein propose a HEAL Data2Action Research Adoption Support Center (RASC). The main purpose of the RASC is to stem the tide of overdose death in the US by leading a scientifically-driven support endeavor designed to effectively translate evidence- based interventions for substance use disorders and pain. Presently, overdose death escalates. Dissemination and implementation (D&I) science is the methodological bridge to both the scientific and public health gaps. Yet D&I science is understudied and underutilized in response to the opioid epidemic. Emblematic of heightened awareness for D&I scientific potential, the HEAL D2A Program will be launched. The program features 10-12 Innovation Projects, and, in addition to the RASC, two additional centers: Modeling and Economic Resource Center and Data Infrastructure Support Center. The RASC will optimize and elevate the D&I capability of the overall HD2A program. In this OVERALL component, we document how the RASC is organized into four synergistic and dynamic cores: Administrative, Substance Use Implementation Support Core, Pain Implementation Support Core, and a Research & Evaluation Core. Three overarching specific aims are strategically ordered across the RASC and all its cores follows: To ASSESS the current state of the HD2A Innovation Projects on D&I research capability, and develop an empirically-based catalog of evidence-based and emerging interventions for substance use disorders and pain; to ASSIST on how Innovation Projects can improve D&I methods and measures through on demand technical assistance and the use of an innovative Implementation Support Plan, and to develop SUD and Pain Intervention D&I Resource Guides; and lastly, to ADVANCE the HD2A Innovation Projects toward greater potential for scalability and sustainment. The RASC is led by 4 MPIs with demonstrated track records of D&I research and practice in the fields of substance use and pain interventions: McGovern (Stanford), S. Becker (Brown), W. Becker (Yale) and Brown (Northwestern). The MPIs are joined by complementary expert core co-directors, and have assembled an unmatched roster of highly-qualified leaders in these fields—carefully selected, organized and ready to provide the necessary implementation support across the HD2A program. This RASC meets all the specified requirements as outlined in the RFA. What distinguishes this RASC is our bold ambition to enhance not only the D&I capability of the HEAL HD2A program, but to influence the field far beyond the confines of the HD2A initiative. We intend to elevate the D&I paradigm of substance use and pain intervention research, and thereby ensure ubiquitous and equitable access to proven interventions by the people and communities who need them the most.

总体而言：项目摘要/摘要为了响应美国国立卫生研究院 RFA-DA-22-050，我们在此提出 HEAL Data2Action 研究采用支持中心 (RASC) RASC 的主要目的是遏制药物过量的趋势。通过领导一项科学驱动的支持努力，旨在有效地转化证据，在美国减少死亡目前，药物过量导致的死亡人数不断增加。和实施（D＆I）科学是弥补科学和公共卫生差距的方法桥梁。然而，在应对阿片类药物流行病方面，D&I 科学并未得到充分研究和利用。为了提高对 D&I 科学潜力的认识，将启动 HEAL D2A 计划。拥有 10-12 个创新项目，除了 RASC 之外，还有两个额外的中心：建模和 RASC将优化和提升经济资源中心和数据基础设施支持中心。整个 HD2A 程序的 D&I 能力在这个整体组件中，我们记录了 RASC 的情况。分为四个协同和动态的核心：行政、物质使用实施支持核心、疼痛实施支持核心和研究与评估核心三个总体具体目标。在 RASC 中进行战略性排序，其所有核心如下：评估 HD2A 的当前状态 D&I 研究能力创新项目，并开发基于经验的循证目录以及针对药物滥用障碍和疼痛的新兴干预措施；协助创新项目如何发挥作用通过按需技术援助和使用创新技术改进 D&I 方法和措施实施支持计划，并制定 SUD 和疼痛干预 D&I 资源指南；推进 HD2A 创新项目，以实现更大的可扩展性和可持续性潜力。由 4 个 MPI 领导，在物质使用和领域内具有 D&I 研究和实践的跟踪记录疼痛干预：McGovern（斯坦福大学）、S. Becker（布朗大学）、W. Becker（耶鲁大学）和 Brown（西北大学）。 MPI 由互补的专家核心联合董事加入，并组建了无与伦比的名册这些领域的高素质领导者——经过精心挑选、组织并准备好提供必要的该 RASC 满足整个 HD2A 计划的实施支持。 RFA 中概述了该 RASC 的独特之处在于我们不仅增强 D&I 能力的大胆雄心。 HEAL HD2A 计划的一部分，但我们打算影响该领域远远超出 HD2A 计划的范围。提升物质使用和疼痛干预研究的 D&I 范式，并确保无处不在最需要的人民和社区能够公平地获得经过验证的干预措施。