Pilot Core

试点核心

• 批准号: 10252016
• 负责人: Manney Carrington Reid
• 金额: $ 20.85万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10252016
• 关键词: Address; Adult; Affect; Aging; Basic Science; Behavior Therapy; Behavioral Sciences; Center for Translational Science Activities; Clinical Trials; Collaborations; Development; Effectiveness; Elderly; Ensure; Evaluation; Event; Fostering; Funding; Funding Agency; Generations; Goals; Growth and Development function; HIV; Health; Impaired cognition; Intervention; Lead; Leadership; Life; Measurable; Mentors; Mentorship; Methodology; Methods; Minority; Modeling; Monitor; Pain; Personal Satisfaction; Pilot Projects; Population; Process; Program Development; Quality of life; Reproducibility; Research; Research Activity; Research Institute; Research Methodology; Research Personnel; Resources; Schedule; Science; Series; Site; Social Sciences; Source; Supervision; Technology; Testing; Time; Training; Translating; Translational Research; Underrepresented Populations; United States National Institutes of Health; Work; Writing; base; behavior change; behavioral/social science; career; clinical development; coping; driving behavior; human subject protection; improved; innovation; interest; mHealth; meetings; multidisciplinary; programs; prospective; research data dissemination; rural area; skills; success; symposium; therapy design; therapy development; tool; translational approach; translational pipeline; webinar

Project Summary – Pilot Core The proposed Pilot Core of Cornell’s Roybal Center–The Translational Research Institute on Pain in Later Life (TRIPLL) will maintain and extend the strategies TRIPLL’s pilot and investigator development program employed over the past 5 years to achieve measurable success. We propose to foster translational research activities on pain in later life that lead to the development of potent and scalable interventions based in the science of behavior change (SOBC) using the NIH Stage Model to guide intervention development and progression along the translational pipeline. Cornell’s Roybal Center will focus its translational research efforts on underrepresented populations, i.e., older adults with cognitive impairment, minority elders, older adults living in rural areas, and adults aging with HIV. This focus is appropriate given the disproportionate impact pain has on these populations. TRIPLL’s Pilot Core will bring together methodological leadership from its Management Core, seminars and educational initiatives to achieve its goals of assuring the continued growth and development of mentees towards research independence, ensuring timely project progress and research integrity, developing potent and scalable behavioral interventions, assuring dissemination of research results to appropriate audiences, developing mentee grantsmanship, and providing continued support well beyond completion of the pilot study. Cornell Roybal Center’s overarching goal is to disseminate behavioral interventions that measurably improve the health and well-being of aging adults adversely affected by pain. In the proposed continuation, the specific aims of Cornell’s Pilot Core are to: 1) Foster interest in and career commitment to translating research on the social and behavioral science of behavior change in the context of later-life pain; 2) Fund innovative pilot studies related to the research theme of the center (Pain Coping and Management), consistent with the NIH Stage Model of Intervention Development and driven by theoretical principles in the Science of Behavior Change; 3) Mentor pilot grantees in conducting translational research, 4) Supervise a program of investigator development in the methods of translational research and provide mentorship in intervention development consistent with the NIH Stage Model, and 5) Develop further the capacity for supporting translational research on behavioral intervention development across collaborating sites. The aims of TRIPLL’s Pilot Core are significant because behavior change interventions will ultimately be more effective if the underlying mechanisms driving behavior change are clearly understood. Finally, TRIPLL pilot studies will leverage new theoretical innovations in the social/behavioral sciences to improve the efficacy, effectiveness, and dissemination of interventions implemented in aging populations adversely affected by pain.

项目摘要 – 试点核心 康奈尔大学皇家中心拟议的试点核心——稍后的疼痛转化研究所 Life (TRIPLL) 将维持并扩展该战略 TRIPLL 的试点和研究者发展计划 我们建议在过去 5 年中取得可衡量的成功，以促进转化研究。 针对晚年疼痛的活动，导致基于以下方面的有效且可扩展的干预措施的发展： 行为改变科学 (SOBC) 使用 NIH 阶段模型来指导干预措施的开发和 康奈尔大学皇家中心将重点关注转化研究工作。 针对代表性不足的人群，即有认知障碍的老年人、少数民族老年人、老年人 鉴于不成比例的影响疼痛，这一重点是适当的。 TRIPLL 的试点核心将汇集其方法论领导力。 管理核心、研讨会和教育举措，以实现确保持续增长的目标 和培养受训者走向研究独立性，确保及时的项目进展和研究 诚信，开发有效且可扩展的行为干预措施，确保将研究成果传播到 适当的发展受众、受训者资助，并提供持续的支持 康奈尔皇家中心的首要目标是传播行为学。 显着改善受疼痛不利影响的老年人的健康和福祉的干预措施。 拟议的延续，康奈尔大学试点核心的具体目标是： 1) 培养对转化社会和行为科学研究的兴趣和职业承诺 晚年疼痛背景下的行为改变；2）资助与研究主题相关的创新试点研究； 中心（疼痛应对和管理），与 NIH 干预阶段模型一致 行为改变科学的理论原则的发展和驱动；3) 指导试点受助者 在进行转化研究时，4）按照以下方法监督研究者发展计划 转化研究并为符合 NIH 阶段的干预措施开发提供指导 模型，5）进一步发展支持行为干预转化研究的能力 跨协作站点的开发。 TRIPLL 试点核心的目标意义重大，因为行为改变干预措施最终将 如果清楚地了解驱动行为改变的根本机制，TRIPLL 会更加有效。 试点研究将利用社会/行为科学的新理论创新来提高效率， 在受疼痛不利影响的老龄化人群中实施干预措施的有效性和传播。