CDC/NIOSH for Audiometric Support for 3 NIDCD-Sponsored, Population-Based Surveys

CDC/NIOSH 为 3 项 NIDCD 赞助的基于人群的调查提供听力测量支持

• 批准号: 9004284
• 金额: $ 15.53万
• 依托单位: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9004284
• 关键词: Acoustics; Address; Affect; Agreement; Air; Area; Atherosclerosis; Attention; Audiometry; Beryllium; Bilateral; Blood Pressure; Calibration; Centers for Disease Control and Prevention (U.S.); Child; Classification; Collaborations; Competence; Computer software; Consultations; Country; Data; Data Analyses; Data Collection; Data Element; Data Files; Data Set; Databases; Dementia; Development; Diagnostic; Disease; Ear; Earache; Earwax; Education; Elements; Environment; Equipment; Evaluation; Experimental Designs; Frequencies; Funding; General Population; Genetic; Goals; Government; Health; Health Surveys; Hearing; Heart; Height; Hour; Household; Impaired cognition; Individual; Interview; Investigation; Ipsilateral; Learning; Longitudinal Studies; Maintenance; Manuals; Masks; Measurement; Measures; Methods; Minor; Monitor; National Health and Nutrition Examination Survey; National Institute on Deafness and Other Communication Disorders; Noise; Obesity; Observational Study; Osteoporosis; Otoscopy; Outcome; Physical Examination; Physicians; Population; Predisposition; Printing; Protocols documentation; Pure-Tone Audiometry; Questionnaires; Reporting; Research Institute; Risk Factors; Running; Sampling; Series; Shadowing (Histology); Specific qualifier value; Stroke; Surveys; System; Technical Expertise; Techniques; Test Result; Testing; Time; Training; Tube; Tympanometry; United States National Center for Health Statistics; Visual; Visual impairment; Weight; acoustic reflex; aging gene; attenuation; disease phenotype; early childhood; hearing impairment; kindergarten; middle ear; molecular marker; operation; population based; quality assurance; sarcopenia; screening; sound; statistics; third grade

The purpose of this agreement is to provide funding for scientific and technical support as well as quality assurance of three large audiometric examination surveys funded by NIDCD. These health surveys are: (i) The National Health and Nutrition Examination Survey (NHANES), (ii) Age, Gene/Environment Susceptibility Study–Reykjavik Study (AGES–RS), and (iii) the Early Childhood Longitudinal Study – Kindergarten Class of 2010/2011 (ECLS–K:2010/2011). The Audiometry Components of all three health examination surveys were previously developed by NIDCD in collaboration with NIOSH and other consultants. NIOSH collaborated on the design of the experimental protocol and provided the equipment specifications, oversight of maintenance and calibration, technician training and oversight, operations manual development, and quality assurance for the NHANES. As well, NIOSH provided similar support to AGES and ECLS–K:2010/2011, including setting-up training sessions and observing/monitoring technical competence in obtaining audiometric measurements, technical assistance as needed, and limited quality assurance. The NHANES scientific goals are to establish a statistically accurate, demographically representative baseline on the general health (including Hearing Health) of the U.S. population. NHANES is now a continuous survey and while general health issues are always under investigation such as height, weight, and blood pressure, there are also elements that track individual health outcomes that move in and out of the NHANES as it cycles. NHANES consists of two major components: the household interview and the physical examination in the NHANES Mobile Examination Centers (MECs) that are set up in various areas around the country. The data from the NHANES elements are collected, weighted, and made available to the government and the public as a database on which analysis may be performed. Recently, the data have been released every two years with collaborating agencies receiving the data six months prior to the public release of the data sets. The AGES–RS scientific goals are: 1) to identify genetic and new risk factors for selected diseases including atherosclerosis, cognitive impairment, dementia, stroke, hearing loss, visual impairment, sarcopenia, osteoporosis, and obesity, 2) to characterize phenotypes for these diseases and conditions, and 3) to identify contributory molecular markers associated with these conditions. The proposed ECLS:K-2011 audiometry protocol for the third-grade data collection includes four components: pre-test questions, otoscopy, wideband reflectometry with tympanometry, and pure tone audiometry: (1) Pre-Test Questions: Children will be asked a series of short questions regarding conditions which could affect the test results (cold or earaches, noise exposure within past 24 hours, presence of pe tubes, and whether one ear is better than the other); (2) Otoscopy: Children will receive a brief visual examination of the ear, primarily to assure a clear sound path. In addition, the technicians will note the presence of excessive cerumen or any other gross abnormality which could affect interpretation of audiometric findings. The otoscopic exam will not be diagnostic; it will simply be observational; (3) Wideband Reflectometry, including Tympanometry: An automated wideband reflectometric/tympanometric evaluation of the middle ear will be conducted bilaterally. Analysis and interpretation of the results will be done remotely; (4) Pure Tone Audiometry: Pure tone air conduction thresholds will be obtained bilaterally at 1000, 2000, 3000, 4000, 6000, and 8000 Hz insofar as time and the child’s attention permits. A retest threshold will be obtained in both ears at 2000 Hz as a measure of test reliability. The thresholds will be obtained manually using a modified Hughson-Westlake technique. The first test ear will be alternated to avoid learning effect bias in the thresholds. Frequencies will be tested in a specified order to obtain the more important frequency data first in case time or the child’s attention runs out before all frequencies are completed. All three health surveys share similar hearing exam components, developed collaboratively by NIDCD, NIOSH, NCHS, WESTAT, the Icelandic Heart Association Research Institute, and the Department of Educations, National Center for Education Statistics. The hearing component consists of: 1) a set of questionnaires relating to hearing, noise exposure, and other factors relating to hearing, and 2) audiometric examinations consisting of otoscopy, acoustic immittance (bilateral tympanometry or wide-band reflectometry and screening for ipsilateral acoustic reflexes at 1000 and 2000 Hz), and pure-tone, air-conduction audiometry to determine the hearing thresholds in each ear at several frequencies, such as 500, 1000, 2000, 3000, 4000, 6000, and 8000 Hz. A repeat threshold test is obtained at 1000 Hz or 2000 Hz as a measure of test reliability. When significant inter-ear differences are found, then retests may be performed using insert earphones to maximize the inter-aural attenuation rather than using a noise masker of the non-test ear to obtain what is referred to as masked threshold in the in the test ear to avoid recording of a “shadow audiogram” from the better non-test ear.

本协议的目的是为科学和技术支持提供资金，以及由NIDCD资助的三项大型听力测试调查的质量保证。这些健康调查是：（i）国家健康与营养检查调查（NHANES），（ii）年龄，基因/环境易感性研究 - Reykjavik研究（年龄– RS）和（iii）幼儿纵向研究 - 2010/2011/2011年幼儿园类别（ECLS – K：2010/2011）。 NIDCD先前与NIOSH和其他顾问合作开发了所有三项健康检查调查的听众计量成分。 NIOSH合作了实验协议的设计，并提供了设备规格，维护和校准的监督，技术人员培训和监督，操作手册开发以及NHANES的质量保证。同样，NIOSH为年龄和ECLS – K：2010/2011提供了类似的支持，包括设置培训课程和观察/监测技术能力，以获得听力测量值，根据需要进行技术帮助以及有限的质量保证。 NHANES的科学目标是建立一个统计准确的，人口统计学的代表美国人口一般健康（包括听力健康）的基准。 NHANES现在是一项持续的调查，尽管一般健康问题始终正在调查中，例如身高，体重和血压，但也有一些元素跟踪个人健康成果，这些元素随着IT循环而进出NHANES。 NHANES由两个主要组成部分组成：在全国各个地区设立的NHANES移动检查中心（MEC）的家庭访谈和体格检查。从NHANES元素中收集，加权并提供给政府和公众作为可以进行分析的数据库的数据。最近，该数据每两年发布一次，合作机构在公开发布数据集之前六个月收到数据。 Ages – rs科学目标是：1）确定选定疾病的遗传和新危险因素，包括动脉粥样硬化，认知障碍，痴呆症，中风，听力损失，视觉障碍，肌肉介绍性，骨质疏松症和肥胖症，2）以与这些疾病的表征对这些疾病的表征以及与这些疾病相关性的表征，以及与这些疾病相关的贡献贡献的贡献。 The proposed ECLS:K-2011 audiometry protocol for the third-grade data collection includes four components: pre-test questions, otoscopy, wideband reflectometry with tympanometry, and pure tone audiometry: (1) Pre-Test Questions: Children will be asked a series of short questions Regarding conditions which could affect the test results (cold or eelaches, noise exposure within past 24 hours, presence of pe tubes, and whether one ear is better than the 其他）; （2）耳镜：儿童将对耳朵进行简短的视觉检查，以确保清晰的音轨。此外，技术人员将注意到存在过多的Cerumen或任何其他严重的绝对性，这可能会影响听力测量结果的解释。耳鼻喉检查不会诊断；这将是观察性的； （3）宽带反射法，包括鼓膜法：中耳的自动宽带反射测量法/鼓膜法评估将双侧进行。对结果的分析和解释将进行远程完成； （4）纯音调测量法：纯音空气传导阈值将在1000、2000、3000、4000、6000、6000和8000 Hz的时间和孩子的注意力允许的情况下双侧获得双侧。在2000 Hz的两只耳朵中，将获得重新测试阈值，以衡量测试可靠性。阈值将使用修改后的Hughson-Westlake技术手动获得。第一个测试耳朵将是避免阈值中学习效应偏见的替代方法。频率将以指定的顺序进行测试，以获取更重要的频率数据，或者在所有三项健康调查共享相似的听力考试组件之前，该频率将耗尽。 The hearing component consists of: 1) a set of questionnaires relating to hearing, noise exposure, and other factors relating to hearing, and 2) audiometric examinations consisting of otoscopy, acoustic immittance (bilateral tympanometry or wide-band reflectometry and screening for ipsilateral acoustic reflexes at 1000 and 2000 Hz), and pure-tone, air-conduction audiometry to determine the hearing每个耳朵的阈值以几个频率，例如500、1000、2000、3000、4000、6000和8000 Hz。在1000 Hz或2000 Hz处获得重复阈值测试，以衡量测试可靠性。当发现显着的互伤差异时，可以使用插入耳机进行重新测试，以最大程度地发出耳朵间的衰减，而不是使用非测试耳朵的噪声遮罩器，以获取测试耳朵中所谓的掩盖阈值，以避免从更好的非测试耳中记录“阴影听力”的记录。