Enabling remote medical physics services for medical accelerator quality assurance through a novel, table-top imaging device

通过新颖的桌面成像设备实现远程医学物理服务，以保证医疗加速器的质量

• 批准号: 10256613
• 负责人: Janelle Arlene Molloy
• 金额: $ 39.66万
• 依托单位: WILD DOG PHYSICS, LLC
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10256613
• 关键词: Address; Adoption; Advocate; Appalachian Region; Caliber; Clinic; Clinical; Collection; Data; Data Collection; Dependence; Devices; Dose; Elderly; Ensure; Film; Future; Generations; Geography; Human Resources; Hybrids; Image; Imaging Device; Improve Access; Incidence; Industry Standard; Intensity-Modulated Radiotherapy; International; Kentucky; Light; Linear Accelerator Radiotherapy Systems; Measurement; Measures; Medical; Medical center; Modality; Modernization; Monitor; Optics; Output; Patients; Peer Review; Performance; Phase; Physics; Population; Positioning Attribute; Process; Protocols documentation; Provider; Public Health; Quality Control; Radiation; Radiation therapy; Radio; Radiosurgery; Reporting; Research; Resources; Risk; Rural Community; Safety; Series; Services; Side; Smoking; Surface; System; Techniques; Testing; Time; Tissues; Travel; Universities; Vulnerable Populations; Work; X-Ray Computed Tomography; aged; automated analysis; cost; data acquisition; design; design and construction; dosimetry; health care availability; health care disparity; image guided radiation therapy; improved; improved outcome; innovation; low and middle-income countries; non-compliance; nonmetropolitan area; novel; optical polarization; peer support; phase 2 study; prevent; programs; prototype; public health relevance; quality assurance; recruit; rural area; rural setting; rural underserved; sensor; smoking-related cancer; success; treatment strategy; underserved area; user-friendly

Project Summary / Abstract Radiation therapy is an effective component of the treatment strategy for patients suffering from smoking- related cancers. Advanced techniques such as intensity modulated radiation therapy (IMRT) improve outcomes relative to conventional approaches. Access to this modern treatment modality is limited in Eastern Kentucky, Appalachia and other geographically isolated populations throughout low- and middle-income countries. The broad, long-term objective of this research is improving the accessibility and safety of advanced radiation techniques for patients low-resource settings globally. Quality assurance (QA) programs are required to ensure safe and accurate treatment. The complexity of QA devices is such that their use requires highly specialized human resources (i.e., medical physicists) who must be physically present to collect and analyze data. Providers in these low-resource settings struggle to recruit the necessary staff. This can prevent such clinics from providing IMRT to their patients, even when they own accelerators that are IMRT-capable. Medical Physics Innovations (MPI) proposes to design and construct a user-friendly, affordable QA device that will make high quality QA and precision RT treatments in these low-resource settings more accessible and safe. This proposal will establish feasibility via two specific aims: 1) Build and test the 3 primary subcomponents of an integrated device and 2) Construct and test a clinical prototype. The consolidation of multiple device functions combined with the ease of use and measurement precision enable a paradigm shift if how medical physics services and quality assurance are rendered. Sparse but efficient daily QA protocols will be replaced with comprehensive data collection and automated analysis, at no additional cost in time or staffing. High precision radiation treatments can be safely brought to rural and underserved areas, with safety, efficiency and precision improved in any center using the innovation.

项目概要/摘要 放射治疗是吸烟患者治疗策略的有效组成部分 相关癌症。调强放射治疗 (IMRT) 等先进技术可改善治疗效果 相对于传统方法。在肯塔基州东部，获得这种现代治疗方式的机会有限， 阿巴拉契亚地区和低收入和中等收入国家其他地理上偏僻的人口。这 这项研究的广泛、长期目标是提高先进辐射的可及性和安全性 为全球资源匮乏地区的患者提供技术。需要质量保证 (QA) 计划来确保 安全、准确的治疗。 QA 设备非常复杂，其使用需要高度专业化 必须亲自到场收集和分析数据的人力资源（即医学物理学家）。供应商 在这些资源匮乏的环境中，很难招募到必要的工作人员。这可以防止此类诊所提供 对患者进行 IMRT，即使他们拥有支持 IMRT 的加速器。 医学物理创新 (MPI) 提议设计和构建用户友好、负担得起的 QA 该设备将使这些资源匮乏的环境中的高质量 QA 和精确 RT 治疗变得更加容易 和安全。该提案将通过两个具体目标确定可行性：1）构建并测试 3 个主要项目 集成设备的子组件；2) 构建并测试临床原型。的整合 多种设备功能与易用性和测量精度相结合，可以实现范式转变，如果 如何提供医学物理服务和质量保证。稀疏但高效的日常 QA 协议将 被全面的数据收集和自动分析所取代，无需额外的时间或成本成本 人员配备。高精度放射治疗可以安全地带到农村和服务欠缺的地区，并且安全、 使用这项创新的任何中心的效率和精度都得到了提高。