Low Cost, Fully Implantable Wireless Neural Recording Device

低成本、完全植入式无线神经记录设备

基本信息

批准号：
10255016
负责人：
Roozbeh Ghaffari
金额：
$ 74.81万
依托单位：
NEUROLUX, INC.
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-06-01 至 2023-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10255016
关键词：
3-Dimensional Affect Animal Model Animals Behavior Behavioral Bluetooth Body Temperature Brain Circadian Rhythms Communication Complex Computer software Data Data Display Data Storage and Retrieval Development Devices Electroencephalogram Electroencephalography Electromyography Electronics Electrophysiology (science)Environment Event Harvest Home Impairment Implant Implanted Electrodes Individual Industry Industry Standard Intuition Laboratories Longevity Magnetism Maintenance Manufacturer Name Measurement Methods Miniaturization Mus Muscle Neurosciences Research Outcome Performance Phase Power Sources Printing REM Sleep Rattus Records Rodent Sampling Signal Transduction Sleep Social Interaction System Technology Temperature Temperature Sense Testing Thinness Time Validation Wireless Technology Work awake cost data acquisition data exchange data format design experimental study file format flexibility graphical user interface implantable device improved in vivo evaluation manufacturing process development miniaturize neurophysiology new technology non rapid eye movement operation optogenetics performance tests physiologic stressor printed circuit board programs psychological stressor radio frequency relating to nervous system seal sleep behavior social software systems tool usability user friendly software

项目摘要

Project Summary/Abstract The proposed project will develop a device that records brain and muscle signals (electroencephalography and electromyography, EEG/EMG) from behaving rodents without the cumbersome, expensive, and maintenance- intensive wires or batteries that hinder the usefulness of existing commercially available systems. By delivering both power and data wirelessly, and entirely eliminating all external implants on the animal, our technology will extend brain recording capabilities to sensitive behaviors, such as sleep-wake behavior or social interaction, that are easily disrupted by external tethers, and will enable long-term recordings and recordings from animals behaving in three-dimensional naturalistic environments, that are impossible with current technology. Furthermore, the system we will develop is fully compatible with existing NeuroLux HF wireless electronic platform and control software, allowing us to leverage the strengths of an existing commercial platform to further advance neuroscience research capabilities.

项目概要/摘要拟议的项目将开发一种记录大脑和肌肉信号（脑电图和来自行为啮齿动物的肌电图（EEG/EMG），无需繁琐、昂贵和维护- 密集的电线或电池阻碍了现有商用系统的实用性。通过交付无线供电和数据传输，并完全消除动物身上的所有外部植入物，我们的技术将将大脑记录能力扩展到敏感行为，例如睡眠-觉醒行为或社交互动，很容易被外部系绳破坏，并且可以实现长期记录和动物记录在三维自然环境中表现，这在当前技术下是不可能的。此外，我们将开发的系统与现有的 NeuroLux HF 无线电子设备完全兼容平台和控制软件，使我们能够利用现有商业平台的优势进一步提高神经科学研究能力。