Core A: Administrative and Professional Development Core

核心 A：行政和专业发展核心

基本信息

批准号：
10246818
负责人：
Lucy Liaw
金额：
$ 61.46万
依托单位：
MAINEHEALTH
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-01 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10246818
关键词：
Accounting Administrator Advisory Committees Ants Area Benchmarking Biochemical Pathway Biomedical Research Cellular biology Centers of Research Excellence Clinical Collaborations Communication Contracts Core Facility Counseling Development Disease Doctor of Philosophy Educational workshop Ensure Evaluation Faculty Fostering Goals Grant Hand Health Histopathology Information Services Infrastructure Institutes Lead Leadership Link Maine Medical center Mentors Mentorship Mesenchymal Mesenchymal Stem Cells Metabolic Metabolic Diseases Methods Monitor Neurobiology Nursing Homes Obesity Osteocytes Osteoporosis Outcome Pathway interactions Pharmaceutical Preparations Physiology Pilot Projects Policies Principal Investigator Procedures Productivity Program Development Program Evaluation Proteomics Rattus Regulation Research Research Infrastructure Research Methodology Research Personnel Research Project Grants Resource Development Resources Role Scientist Services Signal Transduction Strategic Planning Structure Tissue Differentiation Tissues Training bone loss career experience fracture risk innovation insight lipid biosynthesis lipidomics neuroregulation neurotransmission novel organizational structure programs relating to nervous system skeletal success tool

项目摘要

The Administrative and Professional Development Core is led by Lucy Liaw and Clifford Rosen, the Principal Investigators of this COBRE program. Our goals as leaders of this COBRE program are to foster and support scientific productivity and collaboration, enhance and coordinate our research infrastructure, seek out and expand scientific expertise, and actively oversee and monitor a professional development program. To accomplish these goals, this Core will 1) provide leadership and scientific expertise in the area of mesenchymal tissue differentiation and signaling and neural interactions in metabolic health and disease, 2) establish a core research group consisting of junior investigators supported by scientific and career mentors, 3) enhance scientific core facilities to support state-of-the-art research methodologies, and 4) administer a collaborative pilot project program. The COBRE consists of four thematically linked projects, and each project leader has two senior research mentors who are experts in the field. Additional advisory networks include an External Advisory Committee consisting of scientific experts and experienced program leaders, and a Steering Committee composed of scientific experts and stakeholders in biomedical research in Maine. Our clinical colleagues at Maine Medical Center will provide translational opportunities and important perspective and guidance on clinical challenges in the areas of metabolic health and disease. To support the advancement of our junior investigators and core facility leaders, we have dedicated professional development resources to support courses, workshops, and an innovative scientist leave program to foster collaboration and training. All of these strategies will support project and core leaders in achieving the benchmarks that are clearly defined within our Center. A robust evaluation program will help promote positive long-term outcomes. The specific aims of this Core and the overall program are: Specific Aim 1. Provide the leadership, governance, and advisory network to establish a new scientific program in mesenchymal progenitor cell biology and neural signaling to gain novel insights into the mechanisms underlying metabolic health and disease. Specific Aim 2. Provide project and mentorship support to launch the careers of promising junior investigators within this scientific program and help ensure their long-term scientific success as independent researchers. Specific Aim 3. Enhance the capabilities of our core facilities to support our COBRE investigators and other institutional and external researchers, and to stimulate innovative research methodologies and new collaborations. Specific Aim 4. Enhance our existing, COBRE-supported pilot project programs to focus on translational opportunities related to metabolic disease.

行政和专业发展核心由 Lucy Liaw 和 Clifford Rosen 领导，该 COBRE 项目的首席研究员。作为 COBRE 计划的领导者，我们的目标是培养支持科学生产力和协作，加强和协调我们的研究基础设施，寻找和扩展科学专业知识，并积极监督和监测专业发展程序。为了实现这些目标，该核心将 1) 提供该领域的领导力和科学专业知识代谢健康和疾病中的间充质组织分化和信号传导以及神经相互作用， 2）建立一个由初级研究人员组成的核心研究小组，并得到科学和职业的支持导师，3) 加强科学核心设施以支持最先进的研究方法，以及 4) 管理协作试点项目计划。 COBRE 由四个主题相关的项目组成，每个项目负责人都有两名资深研究导师，他们都是该领域的专家。额外咨询网络包括一个由科学专家和经验丰富的项目组成的外部咨询委员会领导人以及由生物医学研究领域的科学专家和利益相关者组成的指导委员会在缅因州。我们缅因州医疗中心的临床同事将提供转化机会和关于代谢健康和疾病领域临床挑战的重要观点和指导。到支持我们的初级研究人员和核心设施领导者的进步，我们致力于支持课程、研讨会和创新科学家离职的专业发展资源促进合作和培训的计划。所有这些战略都将支持项目和核心领导者达到我们中心明确规定的基准。强大的评估计划将有助于促进积极的长期成果。该核心和总体计划的具体目标是：具体目标 1. 提供领导、治理和咨询网络，以建立新的科学体系间充质祖细胞生物学和神经信号传导计划，以获得对间充质祖细胞生物学和神经信号传导的新见解代谢健康和疾病的潜在机制。具体目标 2. 提供项目和指导支持，以启动有前途的初级人员的职业生涯该科学计划中的研究人员，并帮助确保他们作为独立的长期科学成功研究人员。具体目标 3. 增强我们核心设施的能力，以支持我们的 COBRE 研究人员和其他机构和外部研究人员，并刺激创新的研究方法和新的合作。具体目标 4. 加强我们现有的、COBRE 支持的试点项目计划，重点关注转化与代谢疾病相关的机会。