Developmental Research Program

发展研究计划

基本信息

批准号：
10247508
负责人：
WILLIAM K PLUNKETT
金额：
$ 6.96万
依托单位：
UNIVERSITY OF TX MD ANDERSON CAN CTR
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-08-05 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10247508
关键词：
Award CD19 gene Cancer Center Caring Clinical Clinical Research Collaborations Communication Development Doctor of Medicine Ensure Environment Fellowship Program Fostering Foundations Funding Goals Grant Guidelines Hypoxia Laboratory Research Leadership Letters Mainstreaming Marrow Mission Modeling Monitor Moon Nature Patients Peer Review Peer Review Grants Pharmaceutical Preparations Pilot Projects Positioning Attribute Process Prognosis Program Research Project Grants Quality of life Research Research Institute Research Peer Review Research Personnel Research Project Grants Scientist Seeds Selection Criteria Source Specimen Stem cell transplant T-Lymphocyte Technology Transfer Texas Time Translating Translational Research Universities cancer prevention career clinically relevant flexibility high reward high risk improved innovation leukemia leukemic stem cell novel programs research study success translational approach whole genome

项目摘要

PROJECT SUMMARY (Developmental Research Program) The specific objectives of the Developmental Research Program are to: 1. Publicize the availability of funds for pilot translational leukemia research studies. 2. Identify through this mechanism innovative projects with significant potential for improving leukemia therapy and prognosis. 3. Encourage collaborations of projects with scientists within the SPORE and outside the SPORE. 4. Enhance the communication between the SPORE leaders and outside investigators to encourage the development of innovative translational strategies in leukemia. 5. Ensure program flexibility so that developmental projects that show promise can be: 1) funded for a second year; 2) encouraged to apply for peer-reviewed funding (i.e. R01); or 3) expanded to become full SPORE projects. The Leukemia SPORE has established, over the past 14 years, clear guidelines and processes for solicitation, selection, and monitoring of the Developmental Research Awards. To achieve our aims, we have developed 1) specific criteria for selection and funding through a peer review mechanism, and 2) mechanisms for close monitoring of, and collaboration between the SPORE leaders and program awardees to enhance the quality of the translational research goals. This resulted in 47 awards given to 34 researchers. The seed money allowed the majority of the funded investigators to pursue independent research in leukemia with peer-reviewed funding. Because of the success of these established mechanisms, we propose to continue them in the next funding period.

项目摘要（发展研究计划）发展研究计划的具体目标是： 1. 公布用于试点转化白血病研究的资金的可用性。 2. 通过该机制识别具有改善白血病治疗巨大潜力的创新项目和预后。 3. 鼓励与 SPORE 内外科学家的项目合作。 4. 加强SPORE领导与外部调查人员之间的沟通，鼓励白血病创新转化策略的发展。 5. 确保计划的灵活性，以便有希望的开发项目能够：1) 获得第二次资助年; 2) 鼓励申请同行评审资助（即R01）；或 3) 扩展成为完整的 SPORE 项目。在过去 14 年里，白血病孢子 (Leukemia SPORE) 制定了明确的征集指南和流程，发展研究奖的选择和监督。为了实现我们的目标，我们开发了 1) 通过同行评审机制选择和资助的具体标准，以及 2) 关闭机制 SPORE 领导者和项目获奖者之间的监督和协作，以提高项目的质量转化研究目标。最终 34 名研究人员获得了 47 项奖项。允许的种子资金大多数受资助的研究人员都在经过同行评审的情况下进行白血病的独立研究资金。由于这些既定机制取得了成功，我们建议在下一步继续采用这些机制资助期限。