Lipid Transport, Bile Acid Synthesis, and Cholesterol Homeostasis

脂质运输、胆汁酸合成和胆固醇稳态

• 批准号: 7907772
• 负责人: WILLIAM M PANDAK
• 金额: --
• 依托单位: VA VETERANS ADMINISTRATION HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7907772
• 关键词: Acetyl-CoA Carboxylase; Affect; American; Animal Model; Atherosclerosis; Attenuated; Bile Acid Biosynthesis Pathway; Bile Acids; Binding; Cells; Cholesterol; Cholesterol Homeostasis; Cirrhosis; Cyclophosphamide; Data; Development; Disease; Endoplasmic Reticulum; Enzymes; Event; Extrahepatic; Fatty Acids; Fatty-acid synthase; Fibrosis; Gene Expression; Genes; Genetic; Hepatic; Hepatocyte; Hereditary Disease; Homeostasis; Hydroxymethylglutaryl-CoA reductase; Hypertriglyceridemia; Impairment; Inflammation; Injury; Intracellular Accumulation of Lipids; Knock-out; Lipids; Liver; Liver cell necrosis; Liver diseases; Mediating; Metabolism; Mitochondria; Modeling; Neurologic; Nuclear Receptors; Pathway interactions; Patient Care; Patients; Peroxisome Proliferator-Activated Receptors; Play; Population; Production; Proteins; Receptor Activation; Regulation; Role; Testing; Time; Tissues; Triglycerides; Variant; Veterans; abstracting; atherogenesis; base; cholesterol biosynthesis; effective therapy; human disease; lipid metabolism; lipid transport; non-alcoholic fatty liver; novel strategies; overexpression; oxidation; prevent; public health relevance; response; sensor; treatment strategy