Preventing Prematurity and Poor Pregnancy Outcomes Training Grant

预防早产和不良妊娠结局培训补助金

• 批准号: 8078734
• 负责人: Judy Lynn Aschner
• 金额: $ 29.82万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8078734
• 关键词: Grant; Pregnancy Outcome; Training; premature; prevent

DESCRIPTION (provided by applicant): This new T-32 application, "Preventing Prematurity and Poor Pregnancy Outcomes Training Grant", from the Division of Neonatology/Department of Pediatrics at Vanderbilt University School of Medicine is for the establishment of a postdoctoral training program for pediatric subspecialty fellows with a research and career focus in (a) developmental and perinatal biology, (b) genetic, environmental and biochemical/molecular causes of birth defects, preterm birth and its sequelae and (c) improvement in birth outcomes through translational, epidemiological, quality improvement and comparative effectiveness research. The long-term goals of this program are to develop physician-scientists and future leaders in perinatal research who will make career-long contributions that will positively impact birth outcomes. The Specific Aims are to identify promising trainees early in pediatric subspecialty fellowship training and provide them with a robust, interdisciplinary research experience under the supervision of a qualified mentor with ready access to adequate laboratory resources, populations or datasets of mothers and infants at risk of poor birth outcomes. This program will capitalize on the vast institutional resources at Vanderbilt including the Vanderbilt CTSA, a plethora of core facilities, the Masters in Public Health and Masters of Science in Clinical Investigation, the Quality Scholars Program and the Vanderbilt Evidence-based Practice Center. Given the strong applicant pool, we propose to fund two positions per year in each of the 2nd and 3rd years of fellowship training with commitment of institutional funds for continued training in a 4th year when desired. A talented group of NIH-funded investigators with proven track records of successful mentorship have been chosen from across multiple disciplines representing the unique research strengths of Vanderbilt University. The program's structured research training will instill the skills and knowledge required to address critical issues in perinatal health outcomes. Promising junior faculty have been identified as "mentors-in-training". A 4 member steering committee and a 6-member advisory committee of intramural and extramural experts in the fields of developmental biology, perinatal health outcomes and physician-scientist training will provide guidance on trainee selection and progress and overall program success. PUBLIC HEALTH RELEVANCE: This new T-32 grant will provide structured training for pediatric subspecialty physician- scientists planning an academic career with a research focus in the causes of preterm birth and disorders arising in the perinatal and newborn period. This program will augment the strong track record in the Division of Neonatology and other pediatric subspecialties at Vanderbilt in producing a diverse and expertly trained workforce of academic pediatricians and biomedical scientists to assume leadership roles to meet the healthcare needs of our Nation's children. This program will provide training in the research methods necessary to address important perinatal health issues and the skills required to successfully engage populations of women and infants in research that will ultimate result in the timely translation of fundamental knowledge into meaningful improvements in birth outcomes.

描述（由申请人提供）：这项新的T-32申请“预防早产和不良怀孕成果培训补助金”，来自范德比尔特大学医学学院的新生儿学/儿科学系，是为建立一项小儿生物学的儿科生物学和职业学会的研究和职业学会，以建立（A）开发和（perinatal和Pernational centement of（a））生物缺陷，早产及其后遗症的生化/分子原因以及（c）通过转化，流行病学，质量改善和比较有效性研究改善出生结果。该计划的长期目标是发展医师科学家和围产期研究的未来领导者，他们将做出长期的贡献，从而对出生成果产生积极影响。具体的目的是在小儿专科奖学金培训中确定有前途的学员，并在合格的导师的监督下为他们提供强大的，跨学科的研究经验，并可以随时获得适当的实验室资源，人群，人口或婴儿数据集，处于较差的出生风险中。该计划将利用范德比尔特（Vanderbilt）的庞大机构资源，包括范德比尔特CTSA，众多核心设施，公共卫生硕士学位和临床研究的科学硕士学位，优质学者计划和范德比尔特循证实践中心。考虑到强大的申请人池，我们建议在第二年和第三年的奖学金培训中每年为两位职位提供资金，并承诺在需要的第四年内继续培训机构资金。从多个学科中选择了一群有才华的NIH资助的调查员，这些调查员已从多个学科中选择了代表范德比尔特大学独特的研究优势的成功导师。该计划的结构化研究培训将灌输解决围产期健康成果中关键问题所需的技能和知识。有前途的初级教师被确定为“培训导师”。一个4个成员指导委员会和一个由6名成员的咨询委员会委员会在发育生物学，围产期健康成果和医师科学家培训领域的壁内和外壁外专家委员会培训中，将为受训者的选择，进步以及整体计划的成功提供指导。 公共卫生相关性：这项新的T-32赠款将为小儿专科医师提供结构化培训 - 计划学术生涯，研究重点是早产的原因和在围产期和新生儿时期引起的疾病。该计划将在范德比尔特（Vanderbilt）的新生儿学和其他儿科亚专业部门的良好往绩中提高良好的往绩，以生产多样化且培训的学术学者和生物医学科学家的劳动力多样化，以扮演领导角色，以满足我们国家孩子的医疗保健需求。该计划将提供所需的研究方法的培训，以解决重要的围产期健康问题以及成功地吸引妇女和婴儿种群进行研究所需的技能，这将最终导致及时将基本知识转化为有意义的出生结果改善。