Training Program in Microbial Pathogenesis

微生物发病机制培训计划

• 批准号: 7940031
• 负责人: Janis J. Weis
• 金额: $ 26.93万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7940031
• 关键词: Pathogenesis; Training Programs; microbial

DESCRIPTION (provided by applicant): This application is a resubmission for renewal of the Training Program in Microbial Pathogenesis at the University of Utah awarded in 2003. The first five years of this award successfully accomplished the goals of enhancing and promoting Microbial Pathogenesis at the University of Utah and providing new training opportunities for graduate students and postdoctoral fellows. An integrated approach, involving laboratories from different departments and disciplines, has resulted in a high level of scientific exchange for the trainees. Faculty with foundations in microbiology, immunology and host responses, infectious disease/epidemiology, HIV biology, ecology of pathogen transmission, and genetics of susceptibility to pathogens, now interact on a regular basis at Training Grant-sponsored events. The first period of the award has resulted in: 1) the development of new courses in Microbial Pathogenesis and Immunology; 2) increased interaction of trainees with speakers at the Microbial Pathogenesis Seminar Series; 3) formation of a new journal club in Microbial Pathogenesis; and 4) the initiation of an Annual Training Grant Retreat with trainee presentations and those of outside expert speakers. These programs have extended to the Microbial Pathogenesis community as a whole. This resubmission provides greater emphasis on plans for monitoring trainee success and program activities, and in preparing trainees for future careers in Microbial Pathogenesis. This included internal and external reviews, and formal feedback from trainees and mentors. We continue to emphasize the importance of scientifically rigorous publications, along with numerous opportunities for academic and career advice. Trainees are prepared to impact important areas of health and research including emerging infectious diseases, molecular genetics of host-pathogen interactions, molecular virology and epidemiology, and involvement of immune responses in host defense and pathological outcomes of infection. AH trainees who have left the Training Grant currently hold positions in research or academics. Based on the success of the first award, we are requesting continued support for 3 pre-doctoral and 3 postdoctoral trainees. RELEVANCE: Microbial Pathogenesis as a discipline covers the critical interactions between infectious pathogens and the human or animal host. Understanding the molecular aspects of these interactions is important for many aspects of health related infectious disease research including molecular pathogenesis, vaccine development, therapeutic cures, and epidemiology. Trainees in our program have a broad exposure to these tonics and are trained as sophisticated investigators in this area.

说明（由申请人提供）：本申请是为更新 2003 年授予的犹他大学微生物发病机制培训计划而重新提交的。该奖项的前五年成功实现了增强和促进该大学微生物发病机制的目标犹他州，并为研究生和博士后研究员提供新的培训机会。涉及不同部门和学科实验室的综合方法为学员带来了高水平的科学交流。拥有微生物学、免疫学和宿主反应、传染病/流行病学、艾滋病毒生物学、病原体传播生态学和病原体易感性遗传学基础的教师现在定期在培训补助金赞助的活动中进行互动。第一期奖项的成果是：1）开发微生物发病机制和免疫学新课程； 2) 增加学员与微生物发病机制研讨会系列演讲者的互动； 3) 成立微生物发病机制新期刊俱乐部； 4) 启动年度培训资助静修活动，并由受训者和外部专家演讲者进行演讲。这些计划已扩展到整个微生物发病机制界。这次重新提交更加强调了监测学员成功和项目活动的计划，以及为学员未来在微生物发病机制领域的职业做好准备。这包括内部和外部审查以及来自学员和导师的正式反馈。我们继续强调科学严谨的出版物的重要性，以及提供大量学术和职业建议的机会。学员准备好影响重要的健康和研究领域，包括新出现的传染病、宿主与病原体相互作用的分子遗传学、分子病毒学和流行病学，以及宿主防御和感染病理结果中免疫反应的参与。离开培训补助金的 AH 学员目前担任研究或学术职务。基于第一个奖项的成功，我们请求继续支持 3 名博士前培训生和 3 名博士后培训生。 相关性：微生物发病机制作为一门学科，涵盖了传染性病原体与人类或动物宿主之间的关键相互作用。了解这些相互作用的分子方面对于健康相关传染病研究的许多方面都很重要，包括分子发病机制、疫苗开发、治疗方法和流行病学。我们项目中的学员广泛接触了这些补品，并接受了该领域经验丰富的调查员的培训。