Training Program in Microbial Pathogenesis

微生物发病机制培训计划

• 批准号: 8111237
• 负责人: Janis J. Weis
• 金额: $ 27.35万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8111237
• 关键词: Pathogenesis; Training Programs; microbial

DESCRIPTION (provided by applicant): This application is a resubmission for renewal of the Training Program in Microbial Pathogenesis at the University of Utah awarded in 2003. The first five years of this award successfully accomplished the goals of enhancing and promoting Microbial Pathogenesis at the University of Utah and providing new training opportunities for graduate students and postdoctoral fellows. An integrated approach, involving laboratories from different departments and disciplines, has resulted in a high level of scientific exchange for the trainees. Faculty with foundations in microbiology, immunology and host responses, infectious disease/epidemiology, HIV biology, ecology of pathogen transmission, and genetics of susceptibility to pathogens, now interact on a regular basis at Training Grant-sponsored events. The first period of the award has resulted in: 1) the development of new courses in Microbial Pathogenesis and Immunology; 2) increased interaction of trainees with speakers at the Microbial Pathogenesis Seminar Series; 3) formation of a new journal club in Microbial Pathogenesis; and 4) the initiation of an Annual Training Grant Retreat with trainee presentations and those of outside expert speakers. These programs have extended to the Microbial Pathogenesis community as a whole. This resubmission provides greater emphasis on plans for monitoring trainee success and program activities, and in preparing trainees for future careers in Microbial Pathogenesis. This included internal and external reviews, and formal feedback from trainees and mentors. We continue to emphasize the importance of scientifically rigorous publications, along with numerous opportunities for academic and career advice. Trainees are prepared to impact important areas of health and research including emerging infectious diseases, molecular genetics of host-pathogen interactions, molecular virology and epidemiology, and involvement of immune responses in host defense and pathological outcomes of infection. AH trainees who have left the Training Grant currently hold positions in research or academics. Based on the success of the first award, we are requesting continued support for 3 pre-doctoral and 3 postdoctoral trainees. RELEVANCE: Microbial Pathogenesis as a discipline covers the critical interactions between infectious pathogens and the human or animal host. Understanding the molecular aspects of these interactions is important for many aspects of health related infectious disease research including molecular pathogenesis, vaccine development, therapeutic cures, and epidemiology. Trainees in our program have a broad exposure to these tonics and are trained as sophisticated investigators in this area.

描述（由申请人提供）：此申请是在2003年授予的犹他大学授予微生物发病机理的培训计划的重新提交。该奖项的前五年成功实现了增强和促进犹他大学的微生物发病机理的目标，并为研究生学生和研究生和博士后家伙提供新的培训机会。涉及来自不同部门和学科的实验室的综合方法，导致对学员进行了高度的科学交流。具有微生物学，免疫学和宿主反应基础的教师，传染病/流行病学，HIV生物学，病原体传播的生态学以及对病原体易感性的遗传学，现在在培训授予赞助的事件中定期进行互动。该奖项的第一阶段导致：1）开发微生物发病机理和免疫学方面的新课程； 2）在微生物发病机理系列中，学员与扬声器的相互作用增加； 3）在微生物发病机理中形成新的期刊俱乐部； 4）与学员演讲和外部专家演讲者的年度培训赠款务虚会启动。这些程序已扩展到整个微生物发病机理界。这种重新提交更加重视监测学员成功和计划活动的计划，并为学员准备未来的微生物发病机理的职业。这包括内部和外部评论，以及受训人员和导师的正式反馈。我们继续强调科学严格的出版物的重要性，以及许多学术和职业建议的机会。学员准备影响健康和研究的重要领域，包括新兴的传染病，宿主病原体相互作用的分子遗传学，分子病毒学和流行病学以及免疫反应参与宿主防御和感染的病理学结果。离开培训补助金的AH学员目前担任研究或学者的职位。根据第一个奖项的成功，我们要求继续支持3名博士后和3名博士后学员。 相关性：作为学科的微生物发病机理涵盖了感染性病原体与人或动物宿主之间的关键相互作用。了解这些相互作用的分子方面对于与健康相关的传染病研究的许多方面很重要，包括分子发病机理，疫苗发育，治疗疗法和流行病学。我们计划中的受训者对这些补品有广泛的接触，并接受了该领域的成熟研究人员的培训。