B-CLL SUBGROUPS: MATURATION STAGE & GENE EXPRESSION

B-CLL 亚群：成熟阶段

• 批准号: 8167214
• 负责人: Nicholas Chiorazzi
• 金额: $ 0.04万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167214
• 关键词: Categories; Chronic Lymphocytic Leukemia; Clinical; Computer Retrieval of Information on Scientific Projects Database; Disease; Funding; Gene Expression; Gene Mutation; Grant; Institution; Patients; Research; Research Personnel; Resources; Source; Staging; Subgroup; United States National Institutes of Health; base; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Recent studies have found that the disease B-type chronic lymphocytic leukemia (B-CLL) can be divided into two subgroups based on lg V gene mutation status and CD 38 expression. The patients in these two groups follow different clinical courses. This proposal is designed to understand more precisely how these two broad categories of B-CLL cases differ.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 最近的研究发现，基于LG V基因突变状态和CD 38表达，可以将疾病B型慢性淋巴细胞性白血病（B-CLL）分为两个亚组。这两组中的患者遵循不同的临床课程。 该提案旨在更准确地了解这两个广泛的B-CLL案例类别的不同。