Lightweight Powered Prosthesis for above-knee amputees

适用于膝上截肢者的轻型动力假肢

基本信息

批准号：
10013276
负责人：
Tommaso Lenzi
金额：
$ 43.98万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-09 至 2025-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10013276
关键词：
Address Affect American Amputation Amputees Ankle Artificial Leg Back Pain Biomechanics Cardiopulmonary Clinic Clinical Clinical Trials Communities Degenerative polyarthritis Development Device Designs Devices Elderly Engineering Equilibrium Gait Generations Goals Health Healthcare Home environment Household Individual Injections Joint Prosthesis Knee Knowledge Laboratories Lead Leg Limb structure Longevity Lower Extremity Measures Mediation Mental Depression Metabolic Microprocessor Mission Movement Muscle Outcome Outcome Measure Patients Physiological Population Positioning Attribute Prosthesis Public Health Quality of life Ramp Rehabilitation therapy Research Research Personnel Residual state Robotics Speed Technology Testing Time Torque Translations Trauma United States National Institutes of Health Walking Weight Gain Work base clinical care design disability burden experimental study foot functional improvement functional outcomes improved improved mobility innovation joint loading light weight novel physically handicapped powered prosthesis walking speed walking stability

项目摘要

Project summary Most of the 400,000 Americans living with an above-knee amputation [3] cannot walk at variable speeds and safely negotiate environmental barriers with their prescribed prostheses [4]. This limited functional mobility severely affects their independence and results in secondary health problems, such as back pain, osteoarthritis, and depression [5]. Powered prostheses have the potential to address these problems by providing energy for climbing on ramps or stairs or standing up from a seated position, and by improving walking stability and foot clearance. However, available powered devices are designed to accommodate the needs of young, strong people, who overwhelmingly lose their limb due to trauma and can already achieve full community ambulation with available passive prostheses. The objective of this proposal is to identify key prosthesis technologies required to improve the mobility level of above-knee amputees form limited (K2) to community (K3) ambulators. Our central hypothesis is that a lightweight powered prosthesis can facilitate a transition into variable-speed ambulation and the negotiation of environmental barriers (K3 level) for those amputee patients who currently function at the upper end of the K2 level. Our previous work has produced the first powered knee and ankle prosthesis [11]–[15] to combine the lightness of a passive device (~5.5 lbs) with the power generation capability of a powered prosthesis (~400 W) [16]–[18]. In addition, we have developed an innovative control framework that automatically synchronizes the movement of the powered prosthesis joints with the movement of the residual leg, while modulating energy injection based on walking speed [19]. These novel lightweight prosthesis technologies have been preliminary validated with able-bodied subjects and young traumatic above-knee amputees (K3-K4 level) walking on level [20] and inclined ground at variable speeds, and climbing up and down stairs [12]. Moreover, our preliminary experiments with three K2 above-knee subjects demonstrate the feasibility of the proposed approach. The rationale for the proposed research is that understanding how lightweight robotic technologies contribute to functional mobility will enable innovative design and prescription of prostheses that address the specific needs of dysvascular and geriatric amputees, resulting in better healthcare, mobility, and quality of life. This contribution is significant because lightweight powered prostheses have the potential to extend longevity and to dramatically improve quality of life for up to a million lower-limb amputees—a population expected to double by 2050. Our approach is innovative because It leverages on a novel prosthesis technology that matches the lightness of available passive prostheses without sacrificing power and torque generation capability to address the specific needs of dysvascular patients for the first time. Cumulatively, this work is expected to provide a comprehensive understanding of the engineering, biomechanical, and clinical factors that contribute to the improvement of functional gait ability of amputee patients from limited to community ambulators.

项目概要 400,000 名膝上截肢患者 [3] 中的大多数人无法以变速行走，并且使用规定的假肢安全地克服环境障碍[4]。严重影响他们的独立性并导致继发性健康问题，如背痛、骨关节炎、动力假肢有可能通过提供能量来解决这些问题。爬上坡道或楼梯或从坐姿站起来，并通过提高行走稳定性和足部然而，可用的动力设备旨在满足年轻、强壮的需求。绝大多数因创伤而失去肢体的人已经可以完全社区行走与可用的被动假肢。该提案的目的是确定提高活动水平所需的关键假肢技术的膝上截肢者形成有限（K2）到社区（K3）的步行者。轻型动力假肢可以促进变速行走和协商的过渡对于目前在 K2 上端功能障碍的截肢患者来说，环境（K3 水平）我们之前的工作已经生产出了第一个动力膝关节和踝关节假体 [11]-[15]，以结合无源设备的重量（约 5.5 磅），具有动力假肢的发电能力（约 400 瓦） [16]–[18]此外，我们开发了一种创新的控制框架，可以自动同步动力假肢关节随着残腿的运动而运动，同时调节能量基于步行速度的注射[19]。经过身体健全受试者和年轻创伤性膝上截肢者（K3-K4 级别）水平行走的验证 [20]和变速倾斜地面，以及上下楼梯[12]。对三名 K2 膝盖以上受试者的实验证明了所提出方法的可行性。拟议研究的基本原理是了解轻型机器人技术如何做出贡献功能移动性将使假肢的创新设计和处方能够满足特定的需求血管障碍和老年截肢者，从而获得更好的医疗保健、活动能力和生活质量。这一贡献意义重大，因为轻型动力假肢有可能延长使用寿命并大幅改善多达 100 万下肢截肢者的生活质量——这一人群预计将到 2050 年将翻一番。我们的方法是创新的，因为它利用了一种新颖的假肢技术，可匹配现有被动假肢的轻便性，无需牺牲功率和扭矩生成能力这项工作有望首次满足血管障碍患者的具体需求。对工程、生物力学和临床因素的全面了解，这些因素有助于截肢患者的功能性步态能力从有限的步行者到社区步行者的改善。