Role of Natural Killer Lytic-Associated Molecule (NKLAM) in Natural Killer Functi

自然杀伤裂解相关分子 (NKLAM) 在自然杀伤功能中的作用

• 批准号: 8123617
• 负责人: JACKI KORNBLUTH
• 金额: $ 33.75万
• 依托单位: SAINT LOUIS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-20 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8123617
• 关键词: Acute Erythroblastic Leukemia; Aftercare; Age; Aging; Antibiotic A23187; Antisense Oligonucleotides; Apoptosis; Apoptosis Promoter; Apoptotic; Applications Grants; Bacteria; Bacterial Proteins; Binding; Biogenesis; Calcium; Caspase; Cell Death; Cell-Mediated Cytolysis; Cells; Cessation of life; Communicable Diseases; Cytolysis; Cytoplasm; Cytoplasmic Granules; Cytotoxic T-Lymphocytes; Disease; Down-Regulation; Effector Cell; Enzymes; Exhibits; Exocytosis; Fingers; Genes; Granzyme; Growth; Healthcare Systems; Host Defense; Immune response; Immune system; In Vitro; Incidence; Infectious Agent; Injection of therapeutic agent; Integral Membrane Protein; Interferons; Interleukin-12; Interleukin-15; Interleukin-2; Interleukins; Ionophores; K-562; K562 Cells; Lipopolysaccharides; Lung; Lymphocyte; Lytic; Macrophage Activation; Malignant Neoplasms; Mediating; Melanoma Cell; Membrane; Messenger RNA; Modeling; Mus; NK Cell Activation; Names; Natural Killer Cells; Neoplasm Metastasis; Normal Statistical Distribution; Phagocytosis; Phagolysosome; Phorbol Esters; Play; Population; Predisposition; Primary carcinoma of the liver cells; Process; Proliferating; Proteins; RNA Interference; Resistance; Rest; Role; Signal Transduction; Spleen; Testing; Therapeutic Intervention; Ubiquitination; Uridine Kinase; Wild Type Mouse; Work; antimicrobial; cell killing; cytokine; cytotoxic; cytotoxicity; in vitro activity; in vivo; interest; killings; macrophage; microbial; neoplastic cell; novel; overexpression; pathogen; perforin; prevent; public health relevance; receptor; research study; response; tumor; tumor growth; ubiquitin ligase; ubiquitin-protein ligase