Pilot Project

试点项目

• 批准号: 8033965
• 负责人: Cathy D. Meade
• 金额: $ 5.34万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8033965
• 关键词: Address; American; Attitude; Award; Awareness; Biological; Blood; Collaborations; Collection; Communication; Communication Tools; Communities; Community Networks; Complex; Consent; Data; Development; Disease; Educational Activities; Educational Intervention; Enrollment; Funding; Genetic; Goals; Human; Individual; Intention; Knowledge; Language; Malignant Neoplasms; Measures; Medical; Medicine; Minority Groups; National Cancer Institute; Pamphlets; Participant; Patients; Perception; Phase; Pilot Projects; Prevention strategy; Process; Randomized Controlled Trials; Recovery; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Specimen; Testing; Tissues; Translational Research; Underserved Population; biobank; cancer care; community based participatory research; design; efficacy testing; human tissue; improved; innovation; instrument; literacy; member; tool

Project Summary: Biobanking is the collection, storage, and processing of human tissue and/or other biological specimens (biospecimens), often combined with medical and personal information, for research. Research indicates that most people have little knowledge about biobanking and may hold misconceptions about its purpose. A better understanding of people's perceptions of biobanking is hampered by the lack of validated instruments to evaluate knowledge about and attitudes towards biospecimen donation and banking. The Tampa Bay Community Cancer Network (TBCCN) has recently initiated research in biobanking, through the ARRA funded TBCCN Community Perceptions on Biobanking Project, which aims to design and produce educational communication priming tools (e.g., booklets, videos) about biospecimen collection and banking for healthy community members. The proposed project is the next step in a line of research aimed at testing the efficacy of English and Spanish language educational priming tools in promoting biospecimen collection and banking being developed through the TBCCN Community Perceptions on Biobanking Project. The specific aims of the proposed study are to: (1): develop and pilot test instruments measuring knowledge of and attitudes toward biospecimen collection and biobanking, as well as intention to enroll in and donate specimens to a biobank; (2) conduct a pilot test evaluating educational communication priming tools in improving patients' knowledge of and attitudes towards cancer-related biobanking, as well as intention to donate biospecimens to a biobank; and (3) explore whether educational communication priming tools increase the rate of consent to donate blood to a biobank. The proposed project addresses gaps by developing and validating instruments to measure knowledge of and attitudes towards biospecimen donation and banking, as well as intention to donate biospecimens to a biobank (Phase 1). Once developed, these instruments will be used to evaluate the educational priming tools developed during the TBCCN Community Perceptions on Biobanking Project through a small randomized controlled trial (Phase 2). This trial will evaluate changes in attitudes toward biobanking, knowledge regarding biobanking, intention to participate in a biobank, and consent for donating blood to a biobank from patients provided either 1) educational communication priming tools about biobanking developed in the TBCCN Community Perceptions on Biobanking Project, or 2) the National Cancer Institute's brochure entitled "Providing Your Tissue for Research: What You Need to Know." The proposed pilot study will provide preliminary data to support a larger study of the superiority of the educational communication priming tools in improving patients' perceptions of biospecimen collection and biobanking

项目摘要：生物群是人类组织和/或其他生物标本（生物镜）的收集，存储和处理，通常与医学和个人信息相结合，以进行研究。研究表明，大多数人对生物群的了解很少，并且可能对其目的有误解。由于缺乏评估对生物环境捐赠和银行业务的知识和态度的验证工具，因此可以更好地理解人们对生物群的看法。 坦帕湾社区癌症网络（TBCCN）最近通过ARRA资助的TBCCN社区对生物群体项目的看法开始了生物群的研究，该项目旨在设计和生产有关生物赛车收集和银行业务的教育交流启动工具（例如，小册子，视频，视频）健康的社区成员。拟议的项目是旨在测试的研究线的下一步 英语和西班牙语教育启动工具在通过TBCCN社区对生物群体项目的看法开发生物循环收集和银行业务方面的功效。拟议的研究的具体目的是：（1）：开发和试点测试工具，测量对生物测量收集和生物群的知识和态度，以及注册和捐赠标本的意图 到生物库； （2）进行试验测试，评估教育交流启动工具，以提高患者对癌症相关生物群的了解和态度，并打算向生物群捐赠生物含量； （3）探索教育通信启动工具是否增加了向生物库捐赠血液的同意率。拟议的项目通过开发和验证工具来解决差距 衡量对生物测量捐赠和银行业务的知识和态度，以及向生物库捐赠生物构成的意图（第1阶段）。一旦开发，这些工具将用于评估TBCCN社区在生物群体项目中开发的教育启动工具通过一项小型随机对照试验（第2阶段）。该试验将评估对生物库的态度的变化，有关生物群的知识，参与生物库的意图以及同意向患者提供血液的同意。 在TBCCN社区对生物群体项目的看法，或2）国家癌症研究所的小册子题为“为您的组织提供研究：您需要知道的内容”。拟议的试点研究将提供初步数据，以支持对教育交流启动工具的优越性进行更大的研究，以改善患者对生物测量收集和生物群的看法