13th Annual Midwest DNA Repair Symposium

第 13 届年度中西部 DNA 修复研讨会

• 批准号: 8129294
• 负责人: Steve M Patrick
• 金额: $ 0.4万
• 依托单位: UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129294
• 关键词: Cell physiology; Collaborations; Communities; DNA Damage; DNA Repair; DNA Repair Pathway; Diagnosis; Extramural Activities; Fees; Fostering; Funding; Genome Stability; Genomics; Goals; Health; Health Sciences; Home environment; Human; Inherited; Institution; Left; Link; Malignant Neoplasms; Michigan; Mutagenesis; Mutation; Oral; Pathway interactions; Postdoctoral Fellow; Prevention; Process; Recruitment Activity; Regulation; Research; Research Personnel; Scientist; Secure; Series; Students; United States National Institutes of Health; Universities; Work; base; cancer prevention; chemotherapeutic agent; cost; dissemination research; graduate student; interest; meetings; peer; posters; programs; repaired; success; symposium; tumorigenesis

DESCRIPTION (provided by applicant): The 13th Annual Midwest DNA Repair Symposium (AMDRS) will take place in Toledo, OH on May 14 - 15, 2011 at the Dana Conference Center on the University of Toledo Health Science campus. The AMDRS started in 1999 at the University of Michigan and has been hosted at various universities across the Midwest every year since then. The Midwest DNA Repair Symposium was originally conceived as a forum to bring together DNA repair researchers from the Midwestern region on an annual basis to discuss ongoing research and to stimulate collaborations. DNA repair is a critical process to maintain genomic stability and remove DNA damage that if left unrepaired, could result in genomic mutations. Disruption of the DNA repair pathways has been linked to many inherited cancers as well as most, if not all sporadic cancers. Understanding these DNA repair pathways and their regulation will have a significant impact on human health. The AMDRS is now in its second decade, and since its inception, this symposia series has been extremely successful. Over the past several years, there have been significant increases in attendance and new collaborations are fostered each year. One of the important factors to this success and the increase in attendance has been to keep the costs of attending this meeting low. To achieve this goal, the organizers for each year hold the symposium at their home institutions and secure both intramural and extramural funding to cover some of the major expenses. The AMDRS is one meeting to which PI's have been able to bring their entire labs to interact with leading scientists in the field and to present their work among peers. The three principle goals of the AMDRS are: 1) to provide a venue for scientists mainly from the Midwestern states, to present and discuss current research in the field of DNA damage, repair and mutagenesis, and to provide opportunities to foster scientific collaborations. (2) To provide students, postdoctoral fellows, and beginning independent investigators the opportunity to present their work to peers and to interact with leaders in the field. (3) To provide an exceptional value of these symposia by keeping them affordable. PUBLIC HEALTH RELEVANCE: DNA repair is composed of several cellular processes that remove damaged DNA for repair. Efficient DNA repair is fundamental to the prevention of cancer, selectively disabling DNA repair pathways is essential for chemotherapeutic strategies against cancer. The dissemination of research findings at a centrally located scientific meeting that is highly focused within the field of DNA Repair is an ideal venue towards collaborative determination of the cause, diagnosis, prevention, and treatment of human cancer.

描述（由申请人提供）：第 13 届年度中西部 DNA 修复研讨会 (AMDRS) 将于 2011 年 5 月 14 日至 15 日在俄亥俄州托莱多托莱多大学健康科学校区的达纳会议中心举行。 AMDRS 于 1999 年在密歇根大学举办，此后每年都会在中西部的多所大学举办。中西部 DNA 修复研讨会最初的构想是作为一个论坛，每年将来自中西部地区的 DNA 修复研究人员聚集在一起，讨论正在进行的研究并促进合作。 DNA 修复是维持基因组稳定性和消除 DNA 损伤的关键过程，如果不修复，可能会导致基因组突变。 DNA 修复途径的破坏与许多遗传性癌症以及大多数（如果不是全部）散发性癌症有关。了解这些 DNA 修复途径及其调控将对人类健康产生重大影响。 AMDRS 现已进入第二个十年，自成立以来，该研讨会系列取得了巨大成功。在过去的几年中，出席人数显着增加，并且每年都会促进新的合作。此次会议取得成功和出席人数增加的重要因素之一是保持参加本次会议的较低成本。为了实现这一目标，组织者每年都在自己的机构举办研讨会，并确保校内和校外资金来支付一些主要费用。 AMDRS 是一次 PI 能够带领整个实验室与该领域的领先科学家互动并在同行中展示他们的工作的会议。 AMDRS 的三个主要目标是：1）为主要来自中西部各州的科学家提供一个场所，展示和讨论 DNA 损伤、修复和诱变领域的当前研究，并提供促进科学合作的机会。 (2) 为学生、博士后和刚起步的独立研究人员提供向同行展示其工作并与该领域的领导者互动的机会。 (3) 通过保持负担得起来提供这些研讨会的非凡价值。 公共健康相关性：DNA 修复由多个细胞过程组成，这些过程可去除受损的 DNA 进行修复。有效的 DNA 修复是预防癌症的基础，选择性地禁用 DNA 修复途径对于癌症化疗策略至关重要。在高度关注 DNA 修复领域的中心科学会议上传播研究成果是协作确定人类癌症的原因、诊断、预防和治疗的理想场所。