Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS)

拉丁裔研究：营养

基本信息

批准号：
8066419
负责人：
Yasmin Mossavar-Rahmani
金额：
$ 78.17万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-04-25 至 2014-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8066419
关键词：
Acculturation Address Age Biological Markers Body Image Body mass index Cardiovascular Diseases Central American Chicago Cholesterol Clinical Complement Consumption Data Diabetes Mellitus Diet Disease Disease Association Dominican Elements Energy Intake Energy Metabolism Ethnic Origin Expenditure Fatty acid glycerol esters Food Frequencies Funding Future Gender Gold Hispanics Indirect Calorimetry Intake Label Latino Logistic Regressions Measurement Measures Methods Mexican Minerals Modeling National Heart, Lung, and Blood Institute Nitrogen Nutrient Outcome Parents Participant Patient Self-Report Physical activity Population Potassium Property Proteins Protocols documentation Puerto Rican Questionnaires Recovery Recruitment Activity Reporting Research Rest Sampling Serum Site Sodium Source South American Specific qualifier value Techniques Testing Triglycerides United States National Institutes of Health Universities Vitamins Water Women&apos s Health cohort community health study fruits and vegetables hazard improved interest novel nutrition physical conditioning psychosocial public health relevance urinary

项目摘要

DESCRIPTION (provided by applicant): Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) Under-reporting of energy intake and expenditure by self-report obscures the relationship between diet, physical activity and health outcomes. Studies using biomarkers have had a small number of Hispanics limiting ability to assess the extent of measurement error and its correlates in the diverse US Hispanic population. This proposed study will be conducted in the Hispanic Community Health Study-Study of Latinos (HCHS-SOL), an NIH-NHLBI funded study of Hispanics/Latinos in the Bronx, Miami, Chicago and San Diego. Disparate rates of disease in the Hispanic population will be addressed in the parent study and the biomarker data derived from the proposed study can improve the precision of dietary and physical activity assessments related to differences found in disease rates among Hispanic/Latino sub-groups. The biomarker data from the proposed study will have the potential to calibrate nutrient and physical activity self-report data to increase reliability of disease association analyses. The principal aims of the proposed study are to: 1) To compare energy and protein data from the 24 hr dietary recall to the gold standard biomarkers Doubly Labeled Water (DLW) for energy and urinary nitrogen for protein in the HCHS-SOL study; to compare physical activity energy expenditure data from study questionnaires to the Actical (an accelerometer for measuring physical activity), DLW and indirect calorimetry. 2) To contrast measurement error properties of: (i) the 24 hr dietary recall; (ii) the 24 hr dietary recall with the addition of the Food Propensity Questionnaire (FPQ) (iii) SOL Physical Activity Questionnaire; (iv) the Tufts University Puerto Rican/Dominican Food Frequency Questionnaire. (Bronx only); 3)To use the fitted measurement error model to produce calibrated intake and physical activity measures on the full HCHS-SOL cohort for use in analyses of clinical outcomes. PUBLIC HEALTH RELEVANCE: Under-reporting of energy intake and expenditure by self-report obscures the relationship between diet, physical activity and health outcomes. Studies using biomarkers have had a small number of Hispanics limiting ability to assess the extent of measurement error and its correlates in the diverse US Hispanic population. This proposed study will be conducted in the Hispanic Community Health Study-Study of Latinos (HCHS-SOL), an NIH-NHLBI funded study of Hispanics/Latinos in the Bronx, Miami, Chicago and San Diego. Disparate rates of disease in the Hispanic population will be addressed in the parent study and the biomarker data derived from the proposed study can improve the precision of dietary and physical activity assessments related to differences found in disease rates among Hispanic/Latino sub-groups. The biomarker data from the proposed study will have the potential to calibrate nutrient and physical activity self-report data to increase reliability of disease association analyses.

描述（由申请人提供）：拉丁美洲人的研究：营养与体育活动评估研究（SOLNAS）通过自我报告对能量摄入和支出的报告掩盖了饮食，体育锻炼和健康结果之间的关系。使用生物标志物的研究具有少量的西班牙裔限制能力来评估测量误差的程度及其在美国各种西班牙裔人群中的相关性。这项拟议的研究将在拉丁美洲人的西班牙裔社区健康研究研究中进行，这是一项NIH-NHLBI资助的西班牙裔/拉丁美洲人的研究，布朗克斯，迈阿密，芝加哥和圣地亚哥。在父母的研究中将解决西班牙裔人群中疾病的不同率，并且从拟议的研究中得出的生物标志物数据可以提高与西班牙裔/拉丁裔亚组中疾病率差异有关的饮食和身体活动评估的精确度。拟议研究的生物标志物数据将有可能校准养分和体育活动自我报告数据以提高疾病关联分析的可靠性。拟议研究的主要目的是：1）在HCHS-SOL研究中，将能量和蛋白质数据从24小时饮食召回到双标记水（DLW）的黄金标准生物标志物（DLW）的蛋白质和尿氮；要比较体育活动能量消耗从研究问卷到作用（用于测量体育活动的加速度计），DLW和间接热量法。 2）与：（i）24小时饮食召回的对比测量误差属性；（ii）添加食品倾向问卷（FPQ）（iii）SOL体育活动问卷的24小时饮食召回；（iv）塔夫茨大学波多黎各/多米尼加食品频率问卷。（仅布朗克斯）; 3）使用拟合的测量误差模型在完整的HCHS-SOL队列上产生校准的摄入量和体育活动测量，以用于分析临床结果。公共卫生相关性：通过自我报告对能量摄入和支出的报告掩盖了饮食，体育锻炼和健康结果之间的关系。使用生物标志物的研究具有少量的西班牙裔限制能力来评估测量误差的程度及其在美国各种西班牙裔人群中的相关性。这项拟议的研究将在拉丁美洲人的西班牙裔社区健康研究研究中进行，这是一项NIH-NHLBI资助的西班牙裔/拉丁美洲人的研究，布朗克斯，迈阿密，芝加哥和圣地亚哥。在父母的研究中将解决西班牙裔人群中疾病的不同率，并且从拟议的研究中得出的生物标志物数据可以提高与西班牙裔/拉丁裔亚组中疾病率差异有关的饮食和身体活动评估的精确度。拟议研究的生物标志物数据将有可能校准养分和体育活动自我报告数据以提高疾病关联分析的可靠性。