Control of Francisella tularensis LVS growth in non-macrophage cell types

控制土拉弗朗西斯菌 LVS 在非巨噬细胞类型中的生长

• 批准号: 8070819
• 金额: $ 6.5万
• 依托单位: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8070819
• 关键词: Blocking Antibodies; Cell Culture Techniques; Francisella; Francisella tularensis; Growth; Immune; Immunohistochemistry; In Vitro; Knockout Mice; Microscopy; T-Lymphocyte; Techniques; cell type; in vivo; mRNA Expression; macrophage

Use established cell culture and microscopy techniques, knockout mice, antibody blocking strategies, immunohistochemistry, and mRNA expression analyses to determine mechanisms of Francisella growth control in these non-macrophage cell types.

使用已建立的细胞培养和显微镜技术，基因敲除小鼠，抗体阻断策略，免疫组织化学和mRNA表达分析，以确定这些非巨噬细胞类型中Francisella生长控制的机制。